DE60129229T2 - Adeno-assoziierte virus-vermittelte übertragung von angiogenesefaktoren - Google Patents
Adeno-assoziierte virus-vermittelte übertragung von angiogenesefaktoren Download PDFInfo
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- DE60129229T2 DE60129229T2 DE60129229T DE60129229T DE60129229T2 DE 60129229 T2 DE60129229 T2 DE 60129229T2 DE 60129229 T DE60129229 T DE 60129229T DE 60129229 T DE60129229 T DE 60129229T DE 60129229 T2 DE60129229 T2 DE 60129229T2
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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| US22605600P | 2000-08-17 | 2000-08-17 | |
| US226056P | 2000-08-17 | ||
| PCT/IB2001/001902 WO2002014487A2 (en) | 2000-08-17 | 2001-08-17 | Adeno-associated virus-mediated delivery of angiogenic factors |
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| DE60129229D1 DE60129229D1 (de) | 2007-08-16 |
| DE60129229T2 true DE60129229T2 (de) | 2008-05-08 |
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| DE60129229T Expired - Lifetime DE60129229T2 (de) | 2000-08-17 | 2001-08-17 | Adeno-assoziierte virus-vermittelte übertragung von angiogenesefaktoren |
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| US (2) | US20020111324A1 (https=) |
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| JP (1) | JP2004506658A (https=) |
| AT (1) | ATE366319T1 (https=) |
| AU (1) | AU2001294096A1 (https=) |
| CA (1) | CA2419245A1 (https=) |
| DE (1) | DE60129229T2 (https=) |
| ES (1) | ES2288993T3 (https=) |
| WO (1) | WO2002014487A2 (https=) |
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| CA2406687A1 (en) * | 2001-11-09 | 2003-05-09 | Transgene S.A. | Chimeric promoters for controlling expression in muscle cells |
| JP2005528362A (ja) * | 2002-03-21 | 2005-09-22 | ユニヴァーシティ オヴ フロリダ | 血管新生の調節法 |
| US20030198620A1 (en) * | 2002-04-16 | 2003-10-23 | Keiya Ozawa | Method of treating amino acid metabolic disorders using recombinant adeno-associated virus virions |
| CN100387723C (zh) * | 2005-12-02 | 2008-05-14 | 浙江大学 | 血管生长素基因重组腺相关病毒载体及制备方法和用途 |
| GB0821834D0 (en) * | 2008-11-28 | 2009-01-07 | Iti Scotland Ltd | Calibration and control method |
| WO2015191508A1 (en) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| SG11201703148TA (en) | 2014-11-05 | 2017-05-30 | Voyager Therapeutics Inc | Aadc polynucleotides for the treatment of parkinson's disease |
| CA3193811A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| CN119876138A (zh) | 2014-11-14 | 2025-04-25 | 沃雅戈治疗公司 | 调节性多核苷酸 |
| HK1245326A1 (zh) | 2014-12-12 | 2018-08-24 | Voyager Therapeutics, Inc. | 用於生产scaav的组合物和方法 |
| CA2973096A1 (en) | 2015-01-06 | 2016-07-14 | Cardiovascular Biotherapeutics, Inc. | Angiogenic treatment of ischemic heart disease |
| AU2016220304B2 (en) | 2015-02-16 | 2019-07-25 | Venturis Therapeutics, Inc. | Therapeutic angiogenesis for treating erectile conditions |
| EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| CA3024449A1 (en) | 2016-05-18 | 2017-11-23 | Voyager Therapeutics, Inc. | Compositions and methods of treating huntington's disease |
| CA3024448C (en) | 2016-05-18 | 2025-09-09 | Voyager Therapeutics, Inc. | MODULATING POLYNUCLEOTIDES |
| WO2018044933A1 (en) | 2016-08-30 | 2018-03-08 | The Regents Of The University Of California | Methods for biomedical targeting and delivery and devices and systems for practicing the same |
| EP3618839A4 (en) | 2017-05-05 | 2021-06-09 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| JP2020518259A (ja) | 2017-05-05 | 2020-06-25 | ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ハンチントン病治療組成物および方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| JP7229989B2 (ja) | 2017-07-17 | 2023-02-28 | ボイジャー セラピューティクス インコーポレイテッド | 軌道アレイガイドシステム |
| JP7221275B2 (ja) | 2017-08-03 | 2023-02-13 | ボイジャー セラピューティクス インコーポレイテッド | Ａａｖを送達するための組成物および方法 |
| US20200263199A1 (en) | 2017-09-29 | 2020-08-20 | Voyager Therapeutics, Inc. | Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery |
| TW202413649A (zh) | 2017-10-16 | 2024-04-01 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
| WO2019079242A1 (en) | 2017-10-16 | 2019-04-25 | Voyager Therapeutics, Inc. | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| SG11202011296VA (en) | 2018-05-15 | 2020-12-30 | Voyager Therapeutics Inc | Compositions and methods for the treatment of parkinson's disease |
| US12281321B2 (en) | 2018-09-28 | 2025-04-22 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| BR112023001456A2 (pt) | 2020-07-27 | 2023-04-11 | Voyager Therapeutics Inc | Composições e métodos para o tratamento de distúrbios neurológicos relacionados à deficiência de beta glicosilceramidase |
| US20230285596A1 (en) | 2020-07-27 | 2023-09-14 | Voyager Therapeutics, Inc | Compositions and methods for the treatment of niemann-pick type c1 disease |
| EP4433490A2 (en) | 2021-11-17 | 2024-09-25 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of neurological disorders related to glucosylceramidase beta deficiency |
| WO2023240236A1 (en) | 2022-06-10 | 2023-12-14 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of spinal muscular atrophy related disorders |
| AU2023427408A1 (en) | 2023-02-02 | 2025-09-04 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of neurological disorders related to glucosylceramidase beta deficiency |
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| US20030148968A1 (en) * | 1995-02-28 | 2003-08-07 | Hammond H. Kirk | Techniques and compositions for treating cardiovascular disease by in vivo gene delivery |
| US6162796A (en) * | 1995-09-27 | 2000-12-19 | The Rockefeller University | Method for transferring genes to the heart using AAV vectors |
| US6004797A (en) * | 1995-11-09 | 1999-12-21 | Avigen, Inc. | Adenovirus helper-free recombinant AAV Virion production |
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| WO1997032990A1 (en) * | 1996-03-04 | 1997-09-12 | Targeted Genetics Corporation | Methods for transducing cells in blood vessels using recombinant aav vectors |
| US6013780A (en) * | 1996-09-06 | 2000-01-11 | Technion Research & Development Co. Ltd. | VEGF145 expression vectors |
| JP2002502608A (ja) * | 1998-02-06 | 2002-01-29 | コラテラル・セラピューティックス・インコーポレイテッド | 血管新生促進因子である血管内皮細胞成長因子：ｖｅｇｆの変異体 |
| AU763049B2 (en) * | 1998-12-28 | 2003-07-10 | Arch Development Corporation | Efficient and stable (in vivo) gene transfer to cardiomyocytes using recombinantadeno-associated virus vectors |
| EP1016726A1 (en) * | 1998-12-30 | 2000-07-05 | Introgene B.V. | Gene therapy to promote angiogenesis |
| JP2003501092A (ja) * | 1999-06-07 | 2003-01-14 | エドワーズ ライフサイエンシーズ コーポレイション | 標的化新脈管形成 |
| US7223406B2 (en) * | 2000-07-21 | 2007-05-29 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
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- 2001-08-17 AT AT01974582T patent/ATE366319T1/de not_active IP Right Cessation
- 2001-08-17 US US09/932,451 patent/US20020111324A1/en not_active Abandoned
- 2001-08-17 WO PCT/IB2001/001902 patent/WO2002014487A2/en not_active Ceased
- 2001-08-17 EP EP01974582A patent/EP1311699B1/en not_active Expired - Lifetime
-
2006
- 2006-05-26 US US11/441,790 patent/US20070128163A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002014487A2 (en) | 2002-02-21 |
| EP1311699A2 (en) | 2003-05-21 |
| DE60129229D1 (de) | 2007-08-16 |
| EP1311699B1 (en) | 2007-07-04 |
| US20020111324A1 (en) | 2002-08-15 |
| AU2001294096A1 (en) | 2002-02-25 |
| ES2288993T3 (es) | 2008-02-01 |
| US20070128163A1 (en) | 2007-06-07 |
| CA2419245A1 (en) | 2002-02-21 |
| WO2002014487A3 (en) | 2003-03-13 |
| ATE366319T1 (de) | 2007-07-15 |
| JP2004506658A (ja) | 2004-03-04 |
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