DE60119714D1 - Peptidderivat - Google Patents
PeptidderivatInfo
- Publication number
- DE60119714D1 DE60119714D1 DE60119714T DE60119714T DE60119714D1 DE 60119714 D1 DE60119714 D1 DE 60119714D1 DE 60119714 T DE60119714 T DE 60119714T DE 60119714 T DE60119714 T DE 60119714T DE 60119714 D1 DE60119714 D1 DE 60119714D1
- Authority
- DE
- Germany
- Prior art keywords
- function regulator
- regulator
- development
- present
- peptide derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000087114 | 2000-03-23 | ||
JP2000087114 | 2000-03-23 | ||
JP2000288891 | 2000-09-19 | ||
JP2000288891 | 2000-09-19 | ||
PCT/JP2001/002278 WO2001070769A1 (fr) | 2000-03-23 | 2001-03-22 | Derive peptidique |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60119714D1 true DE60119714D1 (de) | 2006-06-22 |
DE60119714T2 DE60119714T2 (de) | 2006-09-07 |
Family
ID=26588465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60119714T Expired - Lifetime DE60119714T2 (de) | 2000-03-23 | 2001-03-22 | Peptidderivat |
Country Status (10)
Country | Link |
---|---|
US (1) | US7635751B2 (de) |
EP (1) | EP1270585B1 (de) |
JP (1) | JP4786047B2 (de) |
KR (1) | KR20020081466A (de) |
CN (1) | CN1419563A (de) |
AT (1) | ATE326478T1 (de) |
AU (1) | AU2001242749A1 (de) |
CA (1) | CA2403447A1 (de) |
DE (1) | DE60119714T2 (de) |
WO (1) | WO2001070769A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003063892A1 (fr) * | 2002-01-29 | 2003-08-07 | Takeda Chemical Industries, Ltd. | Utilisation d'apeline |
US8673848B2 (en) | 2012-01-27 | 2014-03-18 | Novartis Ag | Synthetic apelin mimetics for the treatment of heart failure |
EP1967210A4 (de) * | 2005-12-20 | 2009-11-11 | Takeda Pharmaceutical | Neue anwendung von apelin |
RU2303454C1 (ru) * | 2006-06-22 | 2007-07-27 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Средство, нормализующее репродуктивную функцию у женщин, и способ его получения |
EP1903052A3 (de) * | 2006-07-28 | 2008-04-02 | Faust Pharmaceuticals SA | APJ Rezeptor-Liganden und deren Verwendung |
WO2013050441A1 (en) | 2011-10-05 | 2013-04-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical composition for inhibiting or preventing platelet aggregation |
ES2638649T3 (es) | 2011-11-28 | 2017-10-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Composición farmacéutica para su uso en el tratamiento de disfunciones asociadas al envejecimiento |
CA2860740A1 (en) * | 2012-01-09 | 2013-07-18 | Anchor Therapeutics, Inc. | Apj receptor compounds |
UY35144A (es) | 2012-11-20 | 2014-06-30 | Novartis Ag | Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca |
US8921307B2 (en) | 2012-11-20 | 2014-12-30 | Novartis Ag | Synthetic linear apelin mimetics for the treatment of heart failure |
EP3907237A1 (de) | 2012-12-20 | 2021-11-10 | Amgen Inc. | Apj-rezeptor-agonisten und verwendungen davon |
CN105705167A (zh) | 2013-07-25 | 2016-06-22 | 诺华股份有限公司 | 合成的apelin多肽的生物缀合物 |
EP3024845A1 (de) | 2013-07-25 | 2016-06-01 | Novartis AG | Cyclische polypeptide zur behandlung von herzinsuffizienz |
CN104436158A (zh) * | 2013-09-22 | 2015-03-25 | 华中科技大学 | Apelin-13在治疗糖尿病肾病中的应用 |
GB201407532D0 (en) * | 2014-04-29 | 2014-06-11 | Univ Ulster | Apelin analogues |
JP2018507187A (ja) | 2015-01-23 | 2018-03-15 | ノバルティス アーゲー | 改善された半減期を有する合成アペリン脂肪酸コンジュゲート |
ES2805743T3 (es) | 2015-03-24 | 2021-02-15 | Inst Nat Sante Rech Med | Método y composición farmacéutica para uso en el tratamiento de la diabetes |
HUE050317T2 (hu) | 2015-05-20 | 2020-11-30 | Amgen Inc | APJ receptor triazol agonistái |
WO2017140684A2 (en) | 2016-02-15 | 2017-08-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction |
US9988369B2 (en) | 2016-05-03 | 2018-06-05 | Amgen Inc. | Heterocyclic triazole compounds as agonists of the APJ receptor |
WO2018093579A1 (en) | 2016-11-16 | 2018-05-24 | Amgen Inc. | Triazole phenyl compounds as agonists of the apj receptor |
US10736883B2 (en) | 2016-11-16 | 2020-08-11 | Amgen Inc. | Triazole furan compounds as agonists of the APJ receptor |
EP3541804A1 (de) | 2016-11-16 | 2019-09-25 | Amgen Inc. | Cycloalkyl-substituierte triazolverbindungen als agonisten des apj-rezeptors |
US10689367B2 (en) | 2016-11-16 | 2020-06-23 | Amgen Inc. | Triazole pyridyl compounds as agonists of the APJ receptor |
US11046680B1 (en) | 2016-11-16 | 2021-06-29 | Amgen Inc. | Heteroaryl-substituted triazoles as APJ receptor agonists |
MA46824A (fr) | 2016-11-16 | 2019-09-25 | Amgen Inc | Composés de triazole substitués par alkyle en tant qu'agonistes du récepteur apj |
WO2019089335A1 (en) | 2017-11-03 | 2019-05-09 | Amgen Inc. | Fused triazole agonists of the apj receptor |
US11807624B2 (en) | 2018-05-01 | 2023-11-07 | Amgen Inc. | Substituted pyrimidinones as agonists of the APJ receptor |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE164884T1 (de) * | 1992-11-17 | 1998-04-15 | Icos Corp | Neue sieben-transmembran-rezeptor v28 |
DE69838986T2 (de) * | 1997-12-24 | 2009-01-08 | Takeda Pharmaceutical Co. Ltd. | Polypeptide, deren herstellung und verwendung |
US6475718B2 (en) * | 1998-09-08 | 2002-11-05 | Schering Aktiengesellschaft | Methods and compositions for modulating the interaction between the APJ receptor and the HIV virus |
AU5759399A (en) * | 1998-09-25 | 2000-04-17 | Takeda Chemical Industries Ltd. | Peptide derivative |
-
2001
- 2001-03-22 CN CN01807077A patent/CN1419563A/zh active Pending
- 2001-03-22 WO PCT/JP2001/002278 patent/WO2001070769A1/ja active IP Right Grant
- 2001-03-22 KR KR1020027012331A patent/KR20020081466A/ko not_active Application Discontinuation
- 2001-03-22 AU AU2001242749A patent/AU2001242749A1/en not_active Abandoned
- 2001-03-22 AT AT01915695T patent/ATE326478T1/de not_active IP Right Cessation
- 2001-03-22 EP EP01915695A patent/EP1270585B1/de not_active Expired - Lifetime
- 2001-03-22 CA CA002403447A patent/CA2403447A1/en not_active Abandoned
- 2001-03-22 US US10/239,321 patent/US7635751B2/en not_active Expired - Fee Related
- 2001-03-22 DE DE60119714T patent/DE60119714T2/de not_active Expired - Lifetime
- 2001-03-23 JP JP2001084010A patent/JP4786047B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1270585B1 (de) | 2006-05-17 |
EP1270585A4 (de) | 2004-12-15 |
WO2001070769A1 (fr) | 2001-09-27 |
EP1270585A1 (de) | 2003-01-02 |
KR20020081466A (ko) | 2002-10-26 |
JP4786047B2 (ja) | 2011-10-05 |
US20040116336A1 (en) | 2004-06-17 |
ATE326478T1 (de) | 2006-06-15 |
CA2403447A1 (en) | 2001-09-27 |
US7635751B2 (en) | 2009-12-22 |
AU2001242749A1 (en) | 2001-10-03 |
DE60119714T2 (de) | 2006-09-07 |
JP2002167397A (ja) | 2002-06-11 |
CN1419563A (zh) | 2003-05-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |