DE60119552T2 - Isolierte peptide, die an hla-c moleküle binden und deren verwendung - Google Patents

Isolierte peptide, die an hla-c moleküle binden und deren verwendung Download PDF

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Publication number
DE60119552T2
DE60119552T2 DE60119552T DE60119552T DE60119552T2 DE 60119552 T2 DE60119552 T2 DE 60119552T2 DE 60119552 T DE60119552 T DE 60119552T DE 60119552 T DE60119552 T DE 60119552T DE 60119552 T2 DE60119552 T2 DE 60119552T2
Authority
DE
Germany
Prior art keywords
hla
cells
cell
eso
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60119552T
Other languages
German (de)
English (en)
Other versions
DE60119552D1 (de
Inventor
Ludwig Institute for Cancer Rch Sacha New York GNJATIC
J. Lloyd New York OLD
Yasuhiro New York NAGATA
Elke Jager
Yao-Tseng New York CHEN
Alexander Knuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
Cornell Research Foundation Inc
Ludwig Cancer Research
Original Assignee
Ludwig Institute for Cancer Research Ltd
Cornell Research Foundation Inc
Ludwig Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Institute for Cancer Research Ltd, Cornell Research Foundation Inc, Ludwig Cancer Research filed Critical Ludwig Institute for Cancer Research Ltd
Application granted granted Critical
Publication of DE60119552D1 publication Critical patent/DE60119552D1/de
Publication of DE60119552T2 publication Critical patent/DE60119552T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24Antigen-presenting cells [APC]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4267Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K40/4269NY-ESO
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60119552T 2000-09-26 2001-09-24 Isolierte peptide, die an hla-c moleküle binden und deren verwendung Expired - Lifetime DE60119552T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/670,456 US6506875B1 (en) 2000-09-26 2000-09-26 Isolated peptides which bind to HLA-C molecules and uses thereof
US670456 2000-09-26
PCT/US2001/029920 WO2002026778A2 (en) 2000-09-26 2001-09-24 Isolated peptides which bind to hla-c molecules and uses thereof

Publications (2)

Publication Number Publication Date
DE60119552D1 DE60119552D1 (de) 2006-06-14
DE60119552T2 true DE60119552T2 (de) 2007-04-19

Family

ID=24690468

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60119552T Expired - Lifetime DE60119552T2 (de) 2000-09-26 2001-09-24 Isolierte peptide, die an hla-c moleküle binden und deren verwendung

Country Status (9)

Country Link
US (2) US6506875B1 (https=)
EP (1) EP1320609B1 (https=)
JP (1) JP4174570B2 (https=)
CN (1) CN1253572C (https=)
AT (1) ATE325876T1 (https=)
AU (2) AU2001293051B2 (https=)
CA (1) CA2423481C (https=)
DE (1) DE60119552T2 (https=)
WO (1) WO2002026778A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888100B2 (en) * 1996-10-03 2011-02-15 Memorial Sloan-Kettering Cancer Research Isolated nucleic acid molecules which encode immunogenic portions of NY-ESO-1 protein
WO2014207708A2 (en) 2013-06-28 2014-12-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
CN105085616A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种氨基酸序列及其应用
CN105085615A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种多肽序列及其应用
BR112017013574A2 (pt) 2014-12-23 2018-03-06 Verdon Daniel conjugados de aminoácido e peptídeo e usos dos mesmos
EP3419962A4 (en) 2016-02-26 2020-03-11 Auckland Uniservices Limited CONJUGATES OF AMINO ACIDS AND PEPTIDES AND CONJUGATION METHOD
WO2020178738A1 (en) * 2019-03-04 2020-09-10 University Health Network T cell receptors and methods of use thereof
MX2021010541A (es) 2019-03-04 2021-12-15 Univ Health Network Receptores de linfocitos t y metodos de uso de estos.
CN113795586B (zh) 2019-03-25 2026-03-27 大学健康网络 T细胞受体及其使用方法
CN120397921B (zh) * 2025-05-28 2025-12-02 江苏新恒鼎装备制造有限公司 一种具有自锁功能的船用曲轴红套升降平台

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013481A (en) * 1993-07-22 2000-01-11 Ludwig Institute For Cancer Research Isolated, nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof
US6251603B1 (en) * 1996-10-03 2001-06-26 Ludwig Institute For Cancer Research Method for determining status of a cancerous condition by determining antibodies to NY-ESO-1 in a patient sample
AU9572098A (en) * 1997-10-08 1999-04-27 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Novel human cancer antigen ny eso-1/cag-3 and gene encoding same
JP2002509859A (ja) * 1998-01-23 2002-04-02 ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ Hla−a29分子に結合する単離ポリペプチド、それらをコードする分子である核酸、およびそれらの使用
WO2000020445A2 (en) * 1998-10-02 2000-04-13 Ludwig Institute For Cancer Research Tumor antigens and ctl clones isolated by a novel procedure
WO2001062917A1 (en) * 2000-02-22 2001-08-30 Ludwig Institute For Cancer Research Isolated genomic sequences which encode the ny-eso-1 cancer testis tumor antigen and uses thereof

Also Published As

Publication number Publication date
JP4174570B2 (ja) 2008-11-05
US7009035B2 (en) 2006-03-07
CN1253572C (zh) 2006-04-26
CN1476480A (zh) 2004-02-18
JP2004524271A (ja) 2004-08-12
EP1320609B1 (en) 2006-05-10
US20030050451A1 (en) 2003-03-13
AU9305101A (en) 2002-04-08
HK1060594A1 (en) 2004-08-13
AU2001293051B2 (en) 2007-04-26
ATE325876T1 (de) 2006-06-15
EP1320609A2 (en) 2003-06-25
CA2423481C (en) 2008-06-10
WO2002026778A3 (en) 2003-02-13
DE60119552D1 (de) 2006-06-14
WO2002026778A2 (en) 2002-04-04
US6506875B1 (en) 2003-01-14
CA2423481A1 (en) 2002-04-04

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