DE60119552D1 - Isolierte peptide, die an hla-c moleküle binden und deren verwendung - Google Patents

Isolierte peptide, die an hla-c moleküle binden und deren verwendung

Info

Publication number
DE60119552D1
DE60119552D1 DE60119552T DE60119552T DE60119552D1 DE 60119552 D1 DE60119552 D1 DE 60119552D1 DE 60119552 T DE60119552 T DE 60119552T DE 60119552 T DE60119552 T DE 60119552T DE 60119552 D1 DE60119552 D1 DE 60119552D1
Authority
DE
Germany
Prior art keywords
hla
molecules
isolated peptides
peptides binding
restimulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60119552T
Other languages
English (en)
Other versions
DE60119552T2 (de
Inventor
Sacha Gnjatic
Lloyd J Old
Yasuhiro Nagata
Elke Jager
Yao-Tseng Chen
Alexander Knuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell Research Foundation Inc
Ludwig Institute for Cancer Research New York
Original Assignee
Cornell Research Foundation Inc
Ludwig Institute for Cancer Research New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Research Foundation Inc, Ludwig Institute for Cancer Research New York filed Critical Cornell Research Foundation Inc
Publication of DE60119552D1 publication Critical patent/DE60119552D1/de
Application granted granted Critical
Publication of DE60119552T2 publication Critical patent/DE60119552T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464484—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/464488—NY-ESO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
DE60119552T 2000-09-26 2001-09-24 Isolierte peptide, die an hla-c moleküle binden und deren verwendung Expired - Lifetime DE60119552T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/670,456 US6506875B1 (en) 2000-09-26 2000-09-26 Isolated peptides which bind to HLA-C molecules and uses thereof
US670456 2000-09-26
PCT/US2001/029920 WO2002026778A2 (en) 2000-09-26 2001-09-24 Isolated peptides which bind to hla-c molecules and uses thereof

Publications (2)

Publication Number Publication Date
DE60119552D1 true DE60119552D1 (de) 2006-06-14
DE60119552T2 DE60119552T2 (de) 2007-04-19

Family

ID=24690468

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60119552T Expired - Lifetime DE60119552T2 (de) 2000-09-26 2001-09-24 Isolierte peptide, die an hla-c moleküle binden und deren verwendung

Country Status (10)

Country Link
US (2) US6506875B1 (de)
EP (1) EP1320609B1 (de)
JP (1) JP4174570B2 (de)
CN (1) CN1253572C (de)
AT (1) ATE325876T1 (de)
AU (2) AU9305101A (de)
CA (1) CA2423481C (de)
DE (1) DE60119552T2 (de)
HK (1) HK1060594A1 (de)
WO (1) WO2002026778A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888100B2 (en) * 1996-10-03 2011-02-15 Memorial Sloan-Kettering Cancer Research Isolated nucleic acid molecules which encode immunogenic portions of NY-ESO-1 protein
CN105555756B (zh) * 2013-06-28 2018-12-07 奥克兰联合服务有限公司 氨基酸缀合物和肽缀合物及缀合方法
CN105085616A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种氨基酸序列及其应用
CN105085615A (zh) * 2014-05-23 2015-11-25 上海市普陀区中心医院 一种多肽序列及其应用
KR20170094449A (ko) 2014-12-23 2017-08-17 마가렛 앤 브림블 아미노산 및 펩타이드 접합체 및 이들의 용도
CA3014515A1 (en) 2016-02-26 2017-08-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
CN113853434A (zh) * 2019-03-04 2021-12-28 大学健康网络 T细胞受体及其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013481A (en) * 1993-07-22 2000-01-11 Ludwig Institute For Cancer Research Isolated, nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof
US6251603B1 (en) * 1996-10-03 2001-06-26 Ludwig Institute For Cancer Research Method for determining status of a cancerous condition by determining antibodies to NY-ESO-1 in a patient sample
ATE356206T1 (de) * 1997-10-08 2007-03-15 Us Gov Health & Human Serv Menschliches krebsantigen ny eso-1/cag-3 und dazu kodierendes gen
KR20010024877A (ko) * 1998-01-23 2001-03-26 에드워드 에이. 맥더모 2세 분리된, ｈｌａ-ａ29에 결합하는 폴리펩티드, 핵산,이것을 암호화하는 분자, 및 그것의 사용
WO2000020445A2 (en) * 1998-10-02 2000-04-13 Ludwig Institute For Cancer Research Tumor antigens and ctl clones isolated by a novel procedure
WO2001062917A1 (en) * 2000-02-22 2001-08-30 Ludwig Institute For Cancer Research Isolated genomic sequences which encode the ny-eso-1 cancer testis tumor antigen and uses thereof

Also Published As

Publication number Publication date
CA2423481C (en) 2008-06-10
EP1320609A2 (de) 2003-06-25
CA2423481A1 (en) 2002-04-04
US20030050451A1 (en) 2003-03-13
EP1320609B1 (de) 2006-05-10
WO2002026778A3 (en) 2003-02-13
CN1253572C (zh) 2006-04-26
WO2002026778A2 (en) 2002-04-04
US6506875B1 (en) 2003-01-14
HK1060594A1 (en) 2004-08-13
ATE325876T1 (de) 2006-06-15
JP4174570B2 (ja) 2008-11-05
AU2001293051B2 (en) 2007-04-26
AU9305101A (en) 2002-04-08
CN1476480A (zh) 2004-02-18
JP2004524271A (ja) 2004-08-12
DE60119552T2 (de) 2007-04-19
US7009035B2 (en) 2006-03-07

Similar Documents

Publication Publication Date Title
TR199900666T2 (xx) �nsan paratormonu ile ilgili peptidlere kar�� antikor.
BR9713727A (pt) Corpos oleosos e proteìnas associados como matrizes de afinicade.
ES2075196T3 (es) Metodo para el uso y la sintesis de peptidos.
ATE336511T1 (de) Peptide und peptidomimetika mit struktureller ähnlichkeit mit p53 und die die p53-funktion aktivieren
DK0941478T3 (da) Assaymetode for peptidspecifikke T-celler
ATE183514T1 (de) Peptide des menschlichen proteins p53 zum gebrauch in menschlichen-zytotoxischen-t-zell- antwort-induzierenden kompositionen sowie menschliche p53-protein-spezifische t-lymphocyten
ATE387458T1 (de) Fas-antigenbindender ligand
IL123189A0 (en) Colon cell and colon cancer cell associated nucleic acid molecules protein and peptides
EP1708745A4 (de) Antikörper für onkogene stämme von hpv und verfahren zu deren verwendung
DE69333382D1 (de) Hyaluronan rezeptor (rezeptor durch hyaluronan verurzachte bewelichkeit) und hyaluronan bindende peptide
WO2003065003A3 (en) Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof
DE60119552D1 (de) Isolierte peptide, die an hla-c moleküle binden und deren verwendung
ATE362941T1 (de) Identifikation, reinigung und verwendungen von leczymen und karbohydratliganden
HUP0301812A2 (hu) Átvizsgálási (screening) eljárás
WO1999050637A8 (en) Isolated multimeric complexes useful in analysis of t cells, peptides useful in making the complexes, and uses thereof
ATE326981T1 (de) Isolierte peptide die aminosäuresequenzen von ny- eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen
GB2305179A (en) Small cell lung carcinoma peptides and binding agents
DE60025704D1 (de) Das goodpasture-antigen bindende protein
WO2003068800A3 (en) Isolated peptides which bind to hla molecules and uses thereof
ATE405582T1 (de) P53 bindende t-zellrezeptormoleküle und deren verwendungen
DK0667781T3 (da) Peptidbaserede diagnostiske og terapeutiske midler til spondylarthropatier
TR200200631T2 (tr) Alfa-2/Delta geni
WO1992016623A3 (en) Receptors for bombesin-like peptides
EP2385124A3 (de) Peptide oder Peptidanaloga zur Modulation der Bindung zwischen einem PDZ-Protein und einem PL-Protein
DE60038551D1 (de) Peptidepitope die von krankheitsfördernden cd4+ t lymphocyten erkannt werden

Legal Events

Date Code Title Description
8364 No opposition during term of opposition