HUP0301812A2 - Átvizsgálási (screening) eljárás - Google Patents

Átvizsgálási (screening) eljárás

Info

Publication number
HUP0301812A2
HUP0301812A2 HU0301812A HUP0301812A HUP0301812A2 HU P0301812 A2 HUP0301812 A2 HU P0301812A2 HU 0301812 A HU0301812 A HU 0301812A HU P0301812 A HUP0301812 A HU P0301812A HU P0301812 A2 HUP0301812 A2 HU P0301812A2
Authority
HU
Hungary
Prior art keywords
pain
screening method
relates
peptides
vectors
Prior art date
Application number
HU0301812A
Other languages
English (en)
Inventor
Clemens Gillen
M. K. H. Schäfer
E. Weihe
Ingrid Wetzels
Stephan Wnendt
Original Assignee
Grünenthal GmbH.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH. filed Critical Grünenthal GmbH.
Publication of HUP0301812A2 publication Critical patent/HUP0301812A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2842—Pain, e.g. neuropathic pain, psychogenic pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány eljárásra vonatkozik fájdalommal összefüggő, fájdalmatszabályozó anyagok, hozzá társult polinukleotidok, peptidek, fehérjék,vektorok és sejtek megtalálására, vonatkozik továbbá az ezzel azeljárással azonosított vegyületekre, megfelelő gyógyszerekre ésdiagnosztikai reagensekre, és ezek alkalmazására a fájdalomterápiájában. Ó
HU0301812A 2000-08-03 2001-08-03 Átvizsgálási (screening) eljárás HUP0301812A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10037759A DE10037759A1 (de) 2000-08-03 2000-08-03 Screeningverfahren
PCT/EP2001/009011 WO2002012338A2 (de) 2000-08-03 2001-08-03 Screeningverfahren

Publications (1)

Publication Number Publication Date
HUP0301812A2 true HUP0301812A2 (hu) 2003-09-29

Family

ID=7651135

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301812A HUP0301812A2 (hu) 2000-08-03 2001-08-03 Átvizsgálási (screening) eljárás

Country Status (14)

Country Link
US (1) US20040087478A1 (hu)
EP (2) EP1469316B1 (hu)
JP (1) JP2004537962A (hu)
AT (2) ATE344458T1 (hu)
AU (1) AU2001282066A1 (hu)
CA (1) CA2417972A1 (hu)
DE (3) DE10037759A1 (hu)
DK (1) DK1305636T3 (hu)
ES (2) ES2276192T3 (hu)
HU (1) HUP0301812A2 (hu)
MX (1) MXPA03001015A (hu)
PL (1) PL365131A1 (hu)
PT (1) PT1305636E (hu)
WO (1) WO2002012338A2 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1395227B1 (en) * 2001-05-23 2008-05-28 Boehringer Ingelheim Pharmaceuticals Inc. Methods and compounds for the diagnosis of inflammatory disease and identification of pharmacological agents useful in the treatment of inflammatory disease
ES2350089T3 (es) * 2001-06-28 2011-01-18 Millennium Pharmaceuticals, Inc. Un miembro de la familia de las proteína quinasas humanas y usos de la misma.
EP1492553B1 (en) * 2002-03-14 2006-11-22 DeveloGen Aktiengesellschaft Cg8327 and srm involved in the regulation of energy homeostasis
DE10226702A1 (de) * 2002-06-14 2004-09-09 Grünenthal GmbH Antisense Oligonukleotide gegen PIM1
AU2003289947A1 (en) * 2003-02-05 2004-08-30 Grunenthal Gmbh Identification of pain-regulated gene in the dorsal root ganglion (drg) after cfa-induced arthritis
ES2307381B1 (es) 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.
US8642334B2 (en) 2009-02-17 2014-02-04 Memorial Sloan Kettering Cancer Center Methods of neural conversion of human embryonic stem cells
NZ724971A (en) 2010-02-24 2019-06-28 Immunogen Inc Folate receptor 1 antibodies and immunoconjugates and uses thereof
EP3578988A1 (en) * 2010-05-25 2019-12-11 Memorial Sloan-Kettering Cancer Center Method of nociceptor differentiantion of human embryonic stem cells and uses thereof
EP3318273B1 (en) 2011-04-01 2019-08-21 ImmunoGen, Inc. Methods for increasing efficacy of folr1 cancer therapy
AU2012332269B2 (en) 2011-11-04 2018-05-31 Memorial Sloan-Kettering Cancer Center Midbrain dopamine (DA) neurons for engraftment
US20150301068A1 (en) 2012-01-30 2015-10-22 Vib Vzw Means and method for diagnosis and treatment of alzheimer's disease
RS60217B1 (sr) 2012-08-31 2020-06-30 Immunogen Inc Dijagnostički testovi i kompleti za detekciju folatnog receptora 1
WO2014176606A1 (en) 2013-04-26 2014-10-30 Memorial Sloan-Kettering Center Center Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells
RU2725825C2 (ru) 2013-08-30 2020-07-06 Иммьюноджен Инк. Антитела и методы анализа для обнаружения рецептора фолиевой кислоты 1
EP3349796A4 (en) 2015-09-17 2019-05-29 ImmunoGen, Inc. THERAPEUTIC COMBINATIONS COMPRISING ANTI-FOLR1 IMMUNOCONJUGATES
TW201930340A (zh) 2017-12-18 2019-08-01 美商尼恩醫療公司 新抗原及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2148898A1 (en) * 1994-05-09 1995-11-10 John M. Kyriakis P54 stress-activated protein kinases
JPH09163988A (ja) * 1995-10-09 1997-06-24 Kowa Co 新規なｌｄｌ受容体類似蛋白質及び遺伝子
JP2001505779A (ja) * 1996-12-11 2001-05-08 スージェン・インコーポレーテッド Ｐｙｋ２関連産物および方法
DE69824763T2 (de) * 1997-04-07 2005-07-07 Bioimage A/S Verfahren zum Screenen von Substanzen die einen effekt auf intrazelluläre Translokation haben
WO1999012559A1 (en) * 1997-09-09 1999-03-18 The Regents Of The University Of California Inhibition of apoptotis using prosaposin receptor agonists
US6943000B2 (en) * 1997-10-03 2005-09-13 University Of Massachusetts JNK3 modulators and methods of use
US6162613A (en) * 1998-02-18 2000-12-19 Vertex Pharmaceuticals, Inc. Methods for designing inhibitors of serine/threonine-kinases and tyrosine kinases
NZ512986A (en) * 1999-01-20 2004-01-30 Aventis Pharma S Polypeptides derived from JNK3
AU5316900A (en) * 1999-06-03 2000-12-28 Vertex Pharmaceuticals Incorporated Inhibitors of c-jun n-terminal kinases (jnk)
TW200302722A (en) * 2002-02-13 2003-08-16 Astrazeneca Ab Therapeutic agents
AU2003214412A1 (en) * 2002-03-28 2003-10-13 Eisai R & D Management Co., Ltd. 7-azaindoles as inhibitors of c-jun n-terminal kinases for the treatment of neurodegenerative disorders

Also Published As

Publication number Publication date
CA2417972A1 (en) 2003-01-31
DE50111395D1 (de) 2006-12-14
JP2004537962A (ja) 2004-12-24
EP1305636A2 (de) 2003-05-02
ES2276192T3 (es) 2007-06-16
PL365131A1 (en) 2004-12-27
EP1469316B1 (de) 2006-11-02
US20040087478A1 (en) 2004-05-06
WO2002012338A3 (de) 2002-12-19
DE10037759A1 (de) 2002-07-04
DK1305636T3 (da) 2006-07-10
ES2260267T3 (es) 2006-11-01
DE50109087D1 (de) 2006-04-27
ATE344458T1 (de) 2006-11-15
EP1469316A1 (de) 2004-10-20
ATE319092T1 (de) 2006-03-15
EP1305636B1 (de) 2006-03-01
EP1469316A3 (de) 2005-01-05
PT1305636E (pt) 2006-07-31
WO2002012338A2 (de) 2002-02-14
EP1469316A8 (de) 2004-12-15
MXPA03001015A (es) 2004-01-29
AU2001282066A1 (en) 2002-02-18

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees