HUP0301812A2 - Átvizsgálási (screening) eljárás - Google Patents

Átvizsgálási (screening) eljárás

Info

Publication number
HUP0301812A2
HUP0301812A2 HU0301812A HUP0301812A HUP0301812A2 HU P0301812 A2 HUP0301812 A2 HU P0301812A2 HU 0301812 A HU0301812 A HU 0301812A HU P0301812 A HUP0301812 A HU P0301812A HU P0301812 A2 HUP0301812 A2 HU P0301812A2
Authority
HU
Hungary
Prior art keywords
pain
screening method
relates
peptides
vectors
Prior art date
Application number
HU0301812A
Other languages
English (en)
Inventor
Clemens Gillen
M. K. H. Schäfer
E. Weihe
Ingrid Wetzels
Stephan Wnendt
Original Assignee
Grünenthal GmbH.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH. filed Critical Grünenthal GmbH.
Publication of HUP0301812A2 publication Critical patent/HUP0301812A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2842—Pain, e.g. neuropathic pain, psychogenic pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány eljárásra vonatkozik fájdalommal összefüggő, fájdalmatszabályozó anyagok, hozzá társult polinukleotidok, peptidek, fehérjék,vektorok és sejtek megtalálására, vonatkozik továbbá az ezzel azeljárással azonosított vegyületekre, megfelelő gyógyszerekre ésdiagnosztikai reagensekre, és ezek alkalmazására a fájdalomterápiájában. Ó
HU0301812A 2000-08-03 2001-08-03 Átvizsgálási (screening) eljárás HUP0301812A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10037759A DE10037759A1 (de) 2000-08-03 2000-08-03 Screeningverfahren
PCT/EP2001/009011 WO2002012338A2 (de) 2000-08-03 2001-08-03 Screeningverfahren

Publications (1)

Publication Number Publication Date
HUP0301812A2 true HUP0301812A2 (hu) 2003-09-29

Family

ID=7651135

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301812A HUP0301812A2 (hu) 2000-08-03 2001-08-03 Átvizsgálási (screening) eljárás

Country Status (14)

Country Link
US (1) US20040087478A1 (hu)
EP (2) EP1305636B1 (hu)
JP (1) JP2004537962A (hu)
AT (2) ATE344458T1 (hu)
AU (1) AU2001282066A1 (hu)
CA (1) CA2417972A1 (hu)
DE (3) DE10037759A1 (hu)
DK (1) DK1305636T3 (hu)
ES (2) ES2276192T3 (hu)
HU (1) HUP0301812A2 (hu)
MX (1) MXPA03001015A (hu)
PL (1) PL365131A1 (hu)
PT (1) PT1305636E (hu)
WO (1) WO2002012338A2 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE397090T1 (de) * 2001-05-23 2008-06-15 Boehringer Ingelheim Pharma Verfahren und verbindungen zur diagnose von entzündlichen erkrankungen und identifizierung von pharmakologischen mitteln zur behandlung von entzündlichen erkrankungen
WO2003002720A2 (en) * 2001-06-28 2003-01-09 Millennium Pharmaceuticals, Inc. 2150, a human protein kinase family member and uses therefor
ATE345807T1 (de) * 2002-03-14 2006-12-15 Develogen Ag Cg8327 und srm in der regulation von energie- homeostase
DE10226702A1 (de) * 2002-06-14 2004-09-09 Grünenthal GmbH Antisense Oligonukleotide gegen PIM1
AU2003289947A1 (en) * 2003-02-05 2004-08-30 Grunenthal Gmbh Identification of pain-regulated gene in the dorsal root ganglion (drg) after cfa-induced arthritis
ES2307381B1 (es) 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.
US8642334B2 (en) 2009-02-17 2014-02-04 Memorial Sloan Kettering Cancer Center Methods of neural conversion of human embryonic stem cells
EP3196212B1 (en) 2010-02-24 2020-06-03 ImmunoGen, Inc. Immunoconjugates comprising a folate receptor 1 antibody
CA2800500C (en) * 2010-05-25 2019-10-15 Memorial Sloan-Kettering Cancer Center Method of nociceptor differentiation of human embryonic stem cells and uses thereof
EA028805B1 (ru) 2011-04-01 2018-01-31 Иммьюноджен, Инк. Способы повышения эффективности folr1 терапии рака
EP3693455A1 (en) 2011-11-04 2020-08-12 Memorial Sloan-Kettering Cancer Center Midbrain dopamine (da) neurons for engraftment
EP2809800A1 (en) 2012-01-30 2014-12-10 VIB vzw Means and method for diagnosis and treatment of alzheimer's disease
KR20200079565A (ko) 2012-08-31 2020-07-03 이뮤노젠 아이엔씨 엽산 수용체 1의 검출을 위한 진단성 검정 및 키트
EP2989198A4 (en) 2013-04-26 2016-10-26 Sloan Kettering Inst Cancer CORTICAL INTERNEURONES AND OTHER NEURONAL CELLS PRODUCED BY DIRECTED DIFFERENTIATION OF PLURIPOTENT AND MULTIPOTENT CELLS
HUE055856T2 (hu) 2013-08-30 2021-12-28 Immunogen Inc Antitestek és vizsgálatok a folsavreceptor 1 kimutatására
AU2016323968B2 (en) 2015-09-17 2023-07-06 Immunogen, Inc. Therapeutic combinations comprising anti-FOLR1 immunoconjugates
WO2019126186A1 (en) 2017-12-18 2019-06-27 Neon Therapeutics, Inc. Neoantigens and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2148898A1 (en) * 1994-05-09 1995-11-10 John M. Kyriakis P54 stress-activated protein kinases
JPH09163988A (ja) * 1995-10-09 1997-06-24 Kowa Co 新規なｌｄｌ受容体類似蛋白質及び遺伝子
CA2274805A1 (en) * 1996-12-11 1998-06-18 Sugen, Inc. Pyk2 related products and methods
ATE269975T1 (de) * 1997-04-07 2004-07-15 Bioimage As Verfahren zum screenen von substanzen die einen effekt auf intrazelluläre translokation haben
CA2304108A1 (en) * 1997-09-09 1999-03-18 The Regents Of The University Of California Inhibition of apoptotis using prosaposin receptor agonists
US6943000B2 (en) * 1997-10-03 2005-09-13 University Of Massachusetts JNK3 modulators and methods of use
US6162613A (en) * 1998-02-18 2000-12-19 Vertex Pharmaceuticals, Inc. Methods for designing inhibitors of serine/threonine-kinases and tyrosine kinases
WO2000043524A1 (fr) * 1999-01-20 2000-07-27 Aventis Pharma S.A. Polypeptides derives de jnk3
WO2000075118A1 (en) * 1999-06-03 2000-12-14 Vertex Pharmaceuticals Incorporated INHIBITORS OF c-JUN N-TERMINAL KINASES (JNK)
TW200302722A (en) * 2002-02-13 2003-08-16 Astrazeneca Ab Therapeutic agents
WO2003082868A1 (en) * 2002-03-28 2003-10-09 Eisai Co., Ltd. 7-azaindoles as inhibitors of c-jun n-terminal kinases for the treatment of neurodegenerative disorders

Also Published As

Publication number Publication date
ES2260267T3 (es) 2006-11-01
MXPA03001015A (es) 2004-01-29
EP1469316B1 (de) 2006-11-02
EP1305636A2 (de) 2003-05-02
DK1305636T3 (da) 2006-07-10
US20040087478A1 (en) 2004-05-06
ES2276192T3 (es) 2007-06-16
ATE344458T1 (de) 2006-11-15
DE50111395D1 (de) 2006-12-14
EP1469316A3 (de) 2005-01-05
EP1305636B1 (de) 2006-03-01
PL365131A1 (en) 2004-12-27
AU2001282066A1 (en) 2002-02-18
CA2417972A1 (en) 2003-01-31
PT1305636E (pt) 2006-07-31
WO2002012338A2 (de) 2002-02-14
JP2004537962A (ja) 2004-12-24
EP1469316A1 (de) 2004-10-20
EP1469316A8 (de) 2004-12-15
ATE319092T1 (de) 2006-03-15
DE10037759A1 (de) 2002-07-04
WO2002012338A3 (de) 2002-12-19
DE50109087D1 (de) 2006-04-27

Similar Documents

Publication Publication Date Title
HUP0301812A2 (hu) Átvizsgálási (screening) eljárás
MXPA02011656A (es) Moleculas de acido nucleico nrg-2, polipeptidos, y metodos de diagnostico y terapeuticos.
BR0009206A (pt) Isolamento e análise de proteina
HUP0401591A2 (hu) Új receptor-nukleinsavak és- polipeptidek
WO2000078344A8 (en) Prion protein peptides and uses thereof
HUP9802212A2 (hu) Humán terápiában alkalmazható rekombináns anti-CD4-ellenanyagok
IL171109A (en) Glycopagilization methods and proteins / peptides produced by these methods
BRPI0417823A (pt) métodos para uso de bifidobactérias probióticas para animais de estimação
WO2005047904A3 (en) High-density amine-functionalized surface
WO2006069203A3 (en) Methods for proteomic profiling using non-natural amino acids
WO2003104425A3 (en) NEW STABLE ANTI-CD22 ANTIBODIES
DE69931482D1 (de) Isolierte peptide die aminosäuresequenzen von ny-eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen
NZ500216A (en) Beta-amyloid peptide-binding proteins and pharmaceutical use
WO2001029220A3 (en) Mage-a12 antigenic peptides and uses thereof
IL159479A0 (en) Glycopeptides, their preparation and use in the diagnosis or therapeutic treatment of multiple sclerosis
WO2001040291A3 (en) Proteins and nucleic acids encoding the same
GB9811221D0 (en) Bacterial-pheromones and uses therefor
DE69718146T2 (de) At1 rezeptor antagonist zur anregung von apoptosis
WO2001068869A3 (en) Human g-coupled protein receptor kinsaes and polynucleotides encoding the same
WO2001088090A3 (en) Cng3b: a novel cyclic nucleotide-gated cation channel
DE60117788D1 (de) Menschliche wingless-änhliche gene
ATE407944T1 (de) Mit trp-proteinen verwandtes protein mtr1 und dieses codierende dna-sequenz
WO2002101394A3 (de) Screeningverfahren mit bnpi und dnpi
WO2002014467A8 (en) Cng2b: a putative human cyclic nucleotide-gated ion channel
WO2006000464A3 (de) Verfahren zum auffinden schmerzrelevanter substanzen unter verwendung schmerzrelevanter proteine

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees