DE69333382D1 - Hyaluronan rezeptor (rezeptor durch hyaluronan verurzachte bewelichkeit) und hyaluronan bindende peptide - Google Patents
Hyaluronan rezeptor (rezeptor durch hyaluronan verurzachte bewelichkeit) und hyaluronan bindende peptideInfo
- Publication number
- DE69333382D1 DE69333382D1 DE69333382T DE69333382T DE69333382D1 DE 69333382 D1 DE69333382 D1 DE 69333382D1 DE 69333382 T DE69333382 T DE 69333382T DE 69333382 T DE69333382 T DE 69333382T DE 69333382 D1 DE69333382 D1 DE 69333382D1
- Authority
- DE
- Germany
- Prior art keywords
- hyaluronan
- receptor
- binding peptides
- peptides
- receptor protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 title abstract 4
- 229940099552 hyaluronan Drugs 0.000 title abstract 4
- 229920002674 hyaluronan Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000018866 Hyaluronan Receptors Human genes 0.000 title abstract 2
- 108010013214 Hyaluronan Receptors Proteins 0.000 title abstract 2
- 108020003175 receptors Proteins 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 230000009087 cell motility Effects 0.000 abstract 1
- 230000033001 locomotion Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929207949A GB9207949D0 (en) | 1992-04-09 | 1992-04-09 | Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility |
| PCT/CA1993/000158 WO1993021312A1 (en) | 1992-04-09 | 1993-04-13 | Hyaluronan receptor (rhamm = receptor for hyluronan mediated mobility) and hyaluronan binding peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69333382D1 true DE69333382D1 (de) | 2004-02-19 |
| DE69333382T2 DE69333382T2 (de) | 2004-10-21 |
Family
ID=10713846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69333382T Expired - Lifetime DE69333382T2 (de) | 1992-04-09 | 1993-04-13 | Hyaluronan Rezeptor (RHAMM=Rezeptor für durch Hyaluronan verursachte Beweglichkeit) und Hyaluronan bindende Peptide |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0636174B1 (de) |
| AT (1) | ATE257857T1 (de) |
| AU (1) | AU3885793A (de) |
| CA (1) | CA2117747A1 (de) |
| DE (1) | DE69333382T2 (de) |
| GB (1) | GB9207949D0 (de) |
| WO (1) | WO1993021312A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3159595A (en) * | 1994-08-30 | 1996-03-22 | Hyal Pharmaceutical Corporation | Hyaluronic acid and derivatives for modulation of cellular activity |
| GB9420740D0 (en) * | 1994-10-14 | 1994-11-30 | Univ Manitoba | Sequence of the hyaluronan receptor gene |
| US5587301A (en) * | 1995-03-10 | 1996-12-24 | Incyte Pharmaceuticals, Inc. | DNA encoding a hyaluronan receptor expressed in human umbilical vein endothelial cells |
| CA2166155C (en) * | 1995-12-27 | 2008-02-05 | Eva Anne Turley | Agents binding to hyaluronic acid binding domains and the use thereof |
| GB9607441D0 (en) * | 1996-04-10 | 1996-06-12 | Univ Manitoba | Human hyaluronan receptor |
| CA2205771C (en) * | 1997-05-22 | 2002-05-14 | Hyal Pharmaceutical Corporation | Improved delivery of disease modifiers |
| CA2237051A1 (en) | 1997-12-19 | 1999-06-19 | Eva A. Turley | Enhanced affinity hyaluronan binding peptides |
| EP1151012A4 (de) * | 1998-11-19 | 2003-01-08 | Smithkline Beecham Corp | Rhamm antagonistische antikörper |
| US6852696B2 (en) | 1999-03-26 | 2005-02-08 | The University Of Texas System | Inhibitors of glycosaminoglycans |
| DK1165112T3 (da) | 1999-03-26 | 2006-10-09 | Univ Texas | Modulatorer af polysaccharider og anvendelser deraf |
| US6864235B1 (en) | 1999-04-01 | 2005-03-08 | Eva A. Turley | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| US6911429B2 (en) * | 1999-04-01 | 2005-06-28 | Transition Therapeutics Inc. | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| CA2406593A1 (en) * | 2000-04-20 | 2001-11-01 | Cangene Corporation | Rhamm peptide conjugates |
| EP1324765A1 (de) * | 2000-10-05 | 2003-07-09 | Transition Therapeutics Inc. | Zusammensetzungen und verfahren zur beeinflussung der zellulären antwort auf verletzungen und auf andere von hyaladherin und hyaluronan regulierte zellproliferationsstörungen |
| EP3168226A3 (de) | 2010-05-31 | 2017-07-26 | London Health Sciences Centre Research Inc. | Rhamm-bindende peptide |
| US10494402B2 (en) | 2012-11-25 | 2019-12-03 | The Regents Of The University Of California | Peptides that stimulate subcutaneous adipogenesis |
| WO2015184125A1 (en) | 2014-05-28 | 2015-12-03 | The Regents Of The University Of California | Peptides, compositions, and methods for stimulating subcutaneous adipogenesis |
| EP3271383A4 (de) | 2015-03-20 | 2019-06-12 | London Health Sciences Centre Research Inc. | Geheftete peptide und verwendungen davon |
-
1992
- 1992-04-09 GB GB929207949A patent/GB9207949D0/en active Pending
-
1993
- 1993-04-13 AT AT93907733T patent/ATE257857T1/de not_active IP Right Cessation
- 1993-04-13 WO PCT/CA1993/000158 patent/WO1993021312A1/en active IP Right Grant
- 1993-04-13 DE DE69333382T patent/DE69333382T2/de not_active Expired - Lifetime
- 1993-04-13 CA CA002117747A patent/CA2117747A1/en not_active Abandoned
- 1993-04-13 AU AU38857/93A patent/AU3885793A/en not_active Abandoned
- 1993-04-13 EP EP93907733A patent/EP0636174B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE257857T1 (de) | 2004-01-15 |
| AU3885793A (en) | 1993-11-18 |
| EP0636174A1 (de) | 1995-02-01 |
| EP0636174B1 (de) | 2004-01-14 |
| WO1993021312A1 (en) | 1993-10-28 |
| CA2117747A1 (en) | 1993-10-28 |
| GB9207949D0 (en) | 1992-05-27 |
| DE69333382T2 (de) | 2004-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |