DE60117781T2 - Peptidderivate des apolipoproteins-a1/aii - Google Patents
Peptidderivate des apolipoproteins-a1/aii Download PDFInfo
- Publication number
- DE60117781T2 DE60117781T2 DE60117781T DE60117781T DE60117781T2 DE 60117781 T2 DE60117781 T2 DE 60117781T2 DE 60117781 T DE60117781 T DE 60117781T DE 60117781 T DE60117781 T DE 60117781T DE 60117781 T2 DE60117781 T2 DE 60117781T2
- Authority
- DE
- Germany
- Prior art keywords
- peptide
- apo
- domain
- amphipathic helix
- helix peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19892000P | 2000-04-21 | 2000-04-21 | |
| US198920P | 2000-04-21 | ||
| PCT/US2001/013068 WO2001081376A2 (en) | 2000-04-21 | 2001-04-23 | Apo-ai/aii peptide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60117781D1 DE60117781D1 (de) | 2006-05-04 |
| DE60117781T2 true DE60117781T2 (de) | 2006-11-23 |
Family
ID=22735445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60117781T Expired - Lifetime DE60117781T2 (de) | 2000-04-21 | 2001-04-23 | Peptidderivate des apolipoproteins-a1/aii |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6743778B2 (cg-RX-API-DMAC10.html) |
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| MX (1) | MXPA02010324A (cg-RX-API-DMAC10.html) |
| PT (1) | PT1290013E (cg-RX-API-DMAC10.html) |
| WO (1) | WO2001081376A2 (cg-RX-API-DMAC10.html) |
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| JP2003530871A (ja) * | 2000-04-21 | 2003-10-21 | アムジエン・インコーポレーテツド | インテグリン／接着因子アンタゴニスト |
| US8116889B2 (en) * | 2002-06-27 | 2012-02-14 | Openpeak Inc. | Method, system, and computer program product for managing controlled residential or non-residential environments |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| US7329725B1 (en) * | 2003-10-29 | 2008-02-12 | Nastech Pharmaceutical Company Inc. | Phage displayed Trp cage ligands |
| BRPI0406605B8 (pt) | 2003-11-13 | 2021-05-25 | Hanmi Holdings Co Ltd | conjugado de proteína, método para a preparação do mesmo e composição farmacêutica para intensificar a duração e estabilidade in vivo de um polipeptídeo fisiologicamente ativo |
| US8110665B2 (en) | 2003-11-13 | 2012-02-07 | Hanmi Holdings Co., Ltd. | Pharmaceutical composition comprising an immunoglobulin FC region as a carrier |
| KR20070089996A (ko) * | 2004-12-06 | 2007-09-04 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 세동맥의 구조 및 기능의 개선 방법 |
| US7704953B2 (en) * | 2006-02-17 | 2010-04-27 | Mdrna, Inc. | Phage displayed cell binding peptides |
| WO2007103775A2 (en) * | 2006-03-03 | 2007-09-13 | Washington University In St. Louis | Biomaterials having nanoscale layers and coatings |
| ES2402823T3 (es) * | 2006-06-01 | 2013-05-09 | Institut De Cardiologie De Montreal | Compuesto para uso en el tratamiento de estenosis valvular |
| MX2011008599A (es) * | 2009-02-16 | 2011-11-18 | Cerenis Therapeutics Sa | Peptidos mimeticos de la apolipoproteina a-i. |
| AU2014268255B2 (en) * | 2009-02-16 | 2016-04-21 | Cerenis Therapeutics Holding Sa | Apolipoprotein a-i mimics |
| RU2016144908A (ru) | 2014-05-02 | 2018-06-05 | Серени Терапеутикс Холдинг Са | Маркеры hdl-терапии |
| AU2016238290B9 (en) | 2015-03-25 | 2019-06-13 | The Regents Of The University Of Michigan | Compositions and methods for delivery of biomacromolecule agents |
| EP3490579B1 (en) | 2016-07-27 | 2025-09-10 | Hartis-Pharma SA | Therapeutic combinations to treat red blood cell disorders |
| KR20260012291A (ko) | 2018-07-12 | 2026-01-26 | 더 리젠츠 오브 더 유니버시티 오브 미시간 | 면역 반응을 조절할 수 있는 금속 함유 제형의 조성물 및 방법 |
| KR20230004605A (ko) | 2020-04-16 | 2023-01-06 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 급성 상태를 치료하는 방법 |
| CA3197168A1 (en) | 2020-10-01 | 2022-04-07 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CA3216226A1 (en) | 2021-04-15 | 2022-10-20 | Abionyx Pharma Sa | Use of lipid binding protein-based complexes in organ preservation solutions |
| CN119317440A (zh) | 2022-04-06 | 2025-01-14 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗白细胞增多、内皮功能障碍和心脏炎的方法 |
| US20250230208A1 (en) | 2022-04-06 | 2025-07-17 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CA3258787A1 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | METHODS OF TREATMENT OF HYPERINFLAMMATORY DISEASES USING LIPID-BINDING PROTEIN COMPLEXES |
| WO2023237935A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
| KR20260010675A (ko) | 2023-01-13 | 2026-01-21 | 아비오닉스 파마 에스에이 | 지질 결합 단백질 분자 치료 |
| IL327995A (en) | 2023-10-31 | 2026-06-01 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
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| US3941763A (en) | 1975-03-28 | 1976-03-02 | American Home Products Corporation | PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates |
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| US4330440A (en) | 1977-02-08 | 1982-05-18 | Development Finance Corporation Of New Zealand | Activated matrix and method of activation |
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| US4229537A (en) | 1978-02-09 | 1980-10-21 | New York University | Preparation of trichloro-s-triazine activated supports for coupling ligands |
| US4289872A (en) | 1979-04-06 | 1981-09-15 | Allied Corporation | Macromolecular highly branched homogeneous compound based on lysine units |
| US4925673A (en) | 1986-08-18 | 1990-05-15 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents encapsulated with proteinoids |
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| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
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| CA2249195A1 (en) * | 1996-03-18 | 1997-09-25 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
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| EP0934526B1 (en) | 1996-10-08 | 2003-01-08 | U-BISys B.V. | Methods and means for selecting peptides and proteins having specific affinity for a target |
| US6046166A (en) | 1997-09-29 | 2000-04-04 | Jean-Louis Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| GB9815505D0 (en) * | 1998-07-16 | 1998-09-16 | Adprotech Plc | Polypeptide derivatives |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
-
2001
- 2001-04-23 DK DK01930664T patent/DK1290013T3/da active
- 2001-04-23 CA CA002407083A patent/CA2407083A1/en not_active Abandoned
- 2001-04-23 WO PCT/US2001/013068 patent/WO2001081376A2/en not_active Ceased
- 2001-04-23 ES ES01930664T patent/ES2260219T3/es not_active Expired - Lifetime
- 2001-04-23 JP JP2001578463A patent/JP2003530870A/ja not_active Withdrawn
- 2001-04-23 AU AU2001257173A patent/AU2001257173B2/en not_active Ceased
- 2001-04-23 PT PT01930664T patent/PT1290013E/pt unknown
- 2001-04-23 AU AU5717301A patent/AU5717301A/xx active Pending
- 2001-04-23 EP EP01930664A patent/EP1290013B1/en not_active Expired - Lifetime
- 2001-04-23 AT AT01930664T patent/ATE319737T1/de not_active IP Right Cessation
- 2001-04-23 DE DE60117781T patent/DE60117781T2/de not_active Expired - Lifetime
- 2001-04-23 MX MXPA02010324A patent/MXPA02010324A/es unknown
- 2001-04-23 US US09/840,669 patent/US6743778B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6743778B2 (en) | 2004-06-01 |
| EP1290013A2 (en) | 2003-03-12 |
| DK1290013T3 (da) | 2006-06-26 |
| US20030040470A1 (en) | 2003-02-27 |
| AU5717301A (en) | 2001-11-07 |
| AU2001257173B2 (en) | 2005-09-22 |
| WO2001081376A3 (en) | 2003-01-09 |
| JP2003530870A (ja) | 2003-10-21 |
| CA2407083A1 (en) | 2001-11-01 |
| WO2001081376A2 (en) | 2001-11-01 |
| MXPA02010324A (es) | 2003-04-25 |
| DE60117781D1 (de) | 2006-05-04 |
| ATE319737T1 (de) | 2006-03-15 |
| PT1290013E (pt) | 2006-06-30 |
| ES2260219T3 (es) | 2006-11-01 |
| EP1290013B1 (en) | 2006-03-08 |
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