DE60103034T2 - Neue phenylheteroalkylamin-derivate - Google Patents

Neue phenylheteroalkylamin-derivate Download PDF

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Publication number
DE60103034T2
DE60103034T2 DE60103034T DE60103034T DE60103034T2 DE 60103034 T2 DE60103034 T2 DE 60103034T2 DE 60103034 T DE60103034 T DE 60103034T DE 60103034 T DE60103034 T DE 60103034T DE 60103034 T2 DE60103034 T2 DE 60103034T2
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Prior art keywords
chloro
formula
compound
methylamino
alkyl
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Expired - Fee Related
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DE60103034T
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German (de)
English (en)
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DE60103034D1 (de
Inventor
David Loughborough CHESHIRE
Stephen Loughborough CONNOLLY
David Loughborough COX
Antonio Loughborough METE
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AstraZeneca AB
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AstraZeneca AB
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Publication of DE60103034T2 publication Critical patent/DE60103034T2/de
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    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
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    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
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    • C07C217/44—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
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    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Neurology (AREA)
  • Immunology (AREA)
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  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
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  • Hospice & Palliative Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
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DE60103034T 2000-02-23 2001-02-20 Neue phenylheteroalkylamin-derivate Expired - Fee Related DE60103034T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0004152 2000-02-23
GBGB0004152.5A GB0004152D0 (en) 2000-02-23 2000-02-23 Novel compounds
PCT/SE2001/000372 WO2001062714A1 (en) 2000-02-23 2001-02-20 Novel phenylheteroalkylamine derivatives

Publications (2)

Publication Number Publication Date
DE60103034D1 DE60103034D1 (de) 2004-06-03
DE60103034T2 true DE60103034T2 (de) 2005-04-28

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ID=9886164

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DE60103034T Expired - Fee Related DE60103034T2 (de) 2000-02-23 2001-02-20 Neue phenylheteroalkylamin-derivate

Country Status (9)

Country Link
US (1) US6900243B2 (enExample)
EP (1) EP1263715B1 (enExample)
JP (1) JP2003523993A (enExample)
AT (1) ATE265423T1 (enExample)
AU (1) AU2001234314A1 (enExample)
CO (1) CO5261624A1 (enExample)
DE (1) DE60103034T2 (enExample)
GB (1) GB0004152D0 (enExample)
WO (1) WO2001062714A1 (enExample)

Families Citing this family (8)

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AR035700A1 (es) * 2001-05-08 2004-06-23 Astrazeneca Ab Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
AU2003287023A1 (en) 2002-11-05 2004-06-03 Eli Lilly And Company 3-aryloxy/ thio-2, 3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake
WO2004043904A1 (en) 2002-11-05 2004-05-27 Eli Lilly And Company 3-aryloxy/thio-3-substituted propanamines and their use in inhibiting serotonin and norephinephrine reuptake
SE0203304D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Coumpounds
WO2005092835A1 (en) * 2004-03-05 2005-10-06 Eli Lilly And Company Pharmaceutical compounds
JP2008510775A (ja) 2004-08-26 2008-04-10 ノイロサーチ アクティーゼルスカブ モノアミン神経伝達物質再取込み阻害剤としての新規な置換アリールオキシアルキルアミン及びそれらの使用
EP4382529A1 (en) 2022-12-07 2024-06-12 Bayer Consumer Care AG A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride

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JP4716655B2 (ja) 2001-11-21 2011-07-06 ユニバーシティ・オブ・オーフース 抗炎症剤としてのモノ−およびジアシルグリセロールのグリコシドの使用

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EP1263715B1 (en) 2004-04-28
AU2001234314A1 (en) 2001-09-03
US20030065174A1 (en) 2003-04-03
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CO5261624A1 (es) 2003-03-31
WO2001062714A1 (en) 2001-08-30

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