DE60103034T2 - Neue phenylheteroalkylamin-derivate - Google Patents

Neue phenylheteroalkylamin-derivate Download PDF

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Publication number
DE60103034T2
DE60103034T2 DE60103034T DE60103034T DE60103034T2 DE 60103034 T2 DE60103034 T2 DE 60103034T2 DE 60103034 T DE60103034 T DE 60103034T DE 60103034 T DE60103034 T DE 60103034T DE 60103034 T2 DE60103034 T2 DE 60103034T2
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Prior art keywords
chloro
formula
compound
methylamino
alkyl
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Expired - Fee Related
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DE60103034T
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German (de)
English (en)
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DE60103034D1 (de
Inventor
David Loughborough CHESHIRE
Stephen Loughborough CONNOLLY
David Loughborough COX
Antonio Loughborough METE
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AstraZeneca AB
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AstraZeneca AB
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    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
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    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
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    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

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  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
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  • Anesthesiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
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DE60103034T 2000-02-23 2001-02-20 Neue phenylheteroalkylamin-derivate Expired - Fee Related DE60103034T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0004152 2000-02-23
GBGB0004152.5A GB0004152D0 (en) 2000-02-23 2000-02-23 Novel compounds
PCT/SE2001/000372 WO2001062714A1 (en) 2000-02-23 2001-02-20 Novel phenylheteroalkylamine derivatives

Publications (2)

Publication Number Publication Date
DE60103034D1 DE60103034D1 (de) 2004-06-03
DE60103034T2 true DE60103034T2 (de) 2005-04-28

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DE60103034T Expired - Fee Related DE60103034T2 (de) 2000-02-23 2001-02-20 Neue phenylheteroalkylamin-derivate

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Country Link
US (1) US6900243B2 (enExample)
EP (1) EP1263715B1 (enExample)
JP (1) JP2003523993A (enExample)
AT (1) ATE265423T1 (enExample)
AU (1) AU2001234314A1 (enExample)
CO (1) CO5261624A1 (enExample)
DE (1) DE60103034T2 (enExample)
GB (1) GB0004152D0 (enExample)
WO (1) WO2001062714A1 (enExample)

Families Citing this family (8)

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AR035700A1 (es) * 2001-05-08 2004-06-23 Astrazeneca Ab Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
US7417064B2 (en) 2002-11-05 2008-08-26 Eli Lilly And Company 3-aryloxy/thio-3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake
EP1587781A1 (en) 2002-11-05 2005-10-26 Eli Lilly And Company 3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake
SE0203304D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Coumpounds
WO2005092835A1 (en) * 2004-03-05 2005-10-06 Eli Lilly And Company Pharmaceutical compounds
US7973082B2 (en) 2004-08-26 2011-07-05 Neurosearch A/S Substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors
EP4382529A1 (en) 2022-12-07 2024-06-12 Bayer Consumer Care AG A process for preparing pure (3s)-pyrrolidin-3-ol and pure (3s)-pyrrolidin-3-ol hydrochloride

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DE3138550A1 (de) 1981-09-28 1983-04-07 Boehringer Ingelheim KG, 6507 Ingelheim Substituierte 2-phenyl-2-(pyridyloxy)-ethylamine und isostere verbindungen, verfahren zu ihrer herstellung und verwendung
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DK630987D0 (da) 1987-12-01 1987-12-01 Ferrosan As Aryloxyphenylpropylaminer, deres fremstilling og anvendelse
US4902710A (en) * 1988-12-14 1990-02-20 Eli Lilly And Company Serotonin and norepinephrine uptake inhibitors
DK258389D0 (da) 1989-05-26 1989-05-26 Ferrosan As Aryloxyphenylpropylaminer, deres fremstilling og anvendelse
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AU2001234314A1 (en) 2001-09-03
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EP1263715A1 (en) 2002-12-11
ATE265423T1 (de) 2004-05-15
US6900243B2 (en) 2005-05-31
US20030065174A1 (en) 2003-04-03
EP1263715B1 (en) 2004-04-28
WO2001062714A1 (en) 2001-08-30
GB0004152D0 (en) 2000-04-12
CO5261624A1 (es) 2003-03-31

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