DE60044946D1 - Azaindole - Google Patents

Azaindole

Info

Publication number
DE60044946D1
DE60044946D1 DE60044946T DE60044946T DE60044946D1 DE 60044946 D1 DE60044946 D1 DE 60044946D1 DE 60044946 T DE60044946 T DE 60044946T DE 60044946 T DE60044946 T DE 60044946T DE 60044946 D1 DE60044946 D1 DE 60044946D1
Authority
DE
Germany
Prior art keywords
ny3y4
compounds
halo
heteroaryl
cyano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044946T
Other languages
English (en)
Inventor
Paul Joseph Cox
Tahir Nadeem Majid
Justine Yeun Qua Lai
Andrew David Morley
Shelley Amendola
Stephanie Deprets
Chris Aventis Edlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis UK Holdings Ltd
Original Assignee
Aventis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Ltd filed Critical Aventis Pharma Ltd
Priority claimed from PCT/GB2000/004993 external-priority patent/WO2001047922A2/en
Application granted granted Critical
Publication of DE60044946D1 publication Critical patent/DE60044946D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60044946T 1999-12-24 2000-12-27 Azaindole Expired - Lifetime DE60044946D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9930698.7A GB9930698D0 (en) 1999-12-24 1999-12-24 Chemical compounds
US21581800P 2000-07-05 2000-07-05
PCT/GB2000/004993 WO2001047922A2 (en) 1999-12-24 2000-12-27 Azaindoles

Publications (1)

Publication Number Publication Date
DE60044946D1 true DE60044946D1 (de) 2010-10-21

Family

ID=10867079

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60044946T Expired - Lifetime DE60044946D1 (de) 1999-12-24 2000-12-27 Azaindole

Country Status (12)

Country Link
JP (1) JP4871474B2 (de)
AT (2) ATE480537T1 (de)
DE (1) DE60044946D1 (de)
DK (2) DK1263759T3 (de)
ES (2) ES2348861T3 (de)
GB (1) GB9930698D0 (de)
ME (1) MEP49908A (de)
PL (1) PL218884B1 (de)
PT (2) PT1263759E (de)
RS (2) RS51303B (de)
UA (1) UA76410C2 (de)
ZA (1) ZA200204126B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
BRPI0620341A2 (pt) * 2005-12-23 2011-11-08 Smithkline Beecham Corparation azaindóis inibidores de cinases aurora
CL2007002617A1 (es) * 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.
JP5274805B2 (ja) * 2006-09-20 2013-08-28 三菱化学株式会社 フッ素化芳香族化合物の製造方法
ES2464458T3 (es) * 2008-12-05 2014-06-02 F. Hoffmann-La Roche Ag Pirrolopirazinil-ureas como inhibidores de quinasas
CA2771939A1 (en) * 2009-08-26 2011-03-03 Nycomed Gmbh Methylpyrrolopyridinecarboxamides
AU2014231567A1 (en) * 2013-03-14 2015-10-01 Abbvie Inc. Pyrrolo[2,3-b]pyridine CDK9 kinase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0948495T3 (da) * 1996-11-19 2004-06-01 Amgen Inc Aryl- og heteroarylsubstitueret, kondenseret pyrrol som antiinflammatoriske midler
WO1998047899A1 (en) * 1997-04-24 1998-10-29 Ortho-Mcneil Corporation, Inc. Substituted pyrrolopyridines useful in the treatment of inflammatory diseases
ID27124A (id) * 1997-10-20 2001-03-01 Hoffmann La Roche Penghambat kinase bisiklik

Also Published As

Publication number Publication date
DK1990343T3 (da) 2012-07-23
GB9930698D0 (en) 2000-02-16
PT1263759E (pt) 2010-11-02
ES2382759T3 (es) 2012-06-13
RS20100123A (sr) 2010-12-31
ES2348861T3 (es) 2010-12-16
UA76410C2 (en) 2006-08-15
PL218884B1 (pl) 2015-02-27
ATE480537T1 (de) 2010-09-15
JP4871474B2 (ja) 2012-02-08
DK1263759T3 (da) 2011-01-10
ATE552258T1 (de) 2012-04-15
RS51303B (sr) 2010-12-31
YU46202A (sh) 2005-06-10
ZA200204126B (en) 2003-08-25
MEP49908A (en) 2011-02-10
JP2003519144A (ja) 2003-06-17
PT1990343E (pt) 2012-05-22

Similar Documents

Publication Publication Date Title
AP1587A (en) Azaindoles.
HUP0400247A2 (hu) Azaindolok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
TW200612920A (en) Novel imidazolidine derivatives
BR0309710A (pt) Composição ácida espessada e usos da mesma
AP1965A (en) Tropane derivatives useful in therapy.
MXPA03011638A (es) Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
ES2121441T3 (es) Nuevos derivados de 3,5 -dioxo - (2h,4h) - 1,2,4 - triazina,su preparacion y aplicacion como farmaco
RU2007110629A (ru) Ингибиторы днк-пк
TW200607808A (en) Pyrido-pyrimidine derivatives, preparation thereof and application thereof
HK1081194A1 (en) 6-amino-1h-indazole compounds as phosphodiesterase4 inhibitors, pharmaceutical compositions compris ing the same, and use thereof
DE60044946D1 (de) Azaindole
TR200101711T2 (tr) Antihistaminik spiro bileşikler.
EA200500122A1 (ru) Новые соединения, фармацевтические композиции, содержащие их, и способы их использования
GEP20074256B (en) Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing
MEP12108A (en) Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them
EA200400470A1 (ru) Замещенные производные алкиламинопиридазинона, способ их получения и содержащие их фармацевтические композиции
MXPA04003741A (es) Derivados novedosos de hidroxialquil indolocarbazol, metodo de preparacion y composiciones farmaceuticas que los contienen.
NO20035026D0 (no) Dihydroimidazo [5,1-A]-<beta>-karbolinderivater, fremgangsmåte til deres fremstilling og anvendelse derav som legemiddel
GB0114699D0 (en) Organic compounds
DE60026161D1 (de) Amidin-derivate, ihre herstellung und verwendung als medikamenten
GB1016652A (en) Quaternary ammonium compounds and methods for making same
TH37483B (th) อนุพันธ์ 5-เมโรคิลแนพธาลีน
ECSP003505A (es) Derivados de 4-fenil- pirimidina