DE60038248D1 - Mono- und disaccharidderivate - Google Patents

Mono- und disaccharidderivate

Info

Publication number
DE60038248D1
DE60038248D1 DE60038248T DE60038248T DE60038248D1 DE 60038248 D1 DE60038248 D1 DE 60038248D1 DE 60038248 T DE60038248 T DE 60038248T DE 60038248 T DE60038248 T DE 60038248T DE 60038248 D1 DE60038248 D1 DE 60038248D1
Authority
DE
Germany
Prior art keywords
mono
derivatives
disaccharide derivatives
disaccharide
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60038248T
Other languages
English (en)
Other versions
DE60038248T3 (de
DE60038248T2 (de
Inventor
Lucas Alfonsus Hilgers
Anneke Georgine Blom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protherics Medicines Development Ltd
Original Assignee
CoVaccine BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8240940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60038248(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by CoVaccine BV filed Critical CoVaccine BV
Application granted granted Critical
Publication of DE60038248D1 publication Critical patent/DE60038248D1/de
Publication of DE60038248T2 publication Critical patent/DE60038248T2/de
Publication of DE60038248T3 publication Critical patent/DE60038248T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60038248.6T 1999-11-30 2000-11-30 Disaccharidderivate Expired - Lifetime DE60038248T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP99204044A EP1104767A1 (de) 1999-11-30 1999-11-30 Mono- und Disaccharidederivate die sowohl Fettsäureestern als Sulfatestern enthalten
EP99204044 1999-11-30
PCT/NL2000/000878 WO2001040240A2 (en) 1999-11-30 2000-11-30 Mono- and disaccharide derivatives
EP00989042.7A EP1233969B2 (de) 1999-11-30 2000-11-30 Disaccharidderivate

Publications (3)

Publication Number Publication Date
DE60038248D1 true DE60038248D1 (de) 2008-04-17
DE60038248T2 DE60038248T2 (de) 2009-03-12
DE60038248T3 DE60038248T3 (de) 2017-05-18

Family

ID=8240940

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60038248.6T Expired - Lifetime DE60038248T3 (de) 1999-11-30 2000-11-30 Disaccharidderivate

Country Status (12)

Country Link
US (5) US20030220270A1 (de)
EP (2) EP1104767A1 (de)
JP (1) JP5025869B2 (de)
CN (2) CN101108250B (de)
AT (1) ATE388160T1 (de)
AU (1) AU779904B2 (de)
CA (1) CA2393072C (de)
DE (1) DE60038248T3 (de)
DK (1) DK1233969T4 (de)
ES (1) ES2300285T3 (de)
PT (1) PT1233969E (de)
WO (1) WO2001040240A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1682159A4 (de) * 2003-10-16 2010-07-21 Stephen John Ralph Immunomodulierende zusammensetzungen und ihre verwendungen
AU2011211337B2 (en) * 2003-10-16 2014-10-02 Cancure Limited Immunomodulating compositions and uses therefor
FR2878746B1 (fr) 2004-12-02 2007-02-23 Vetoquinol Sa Sa Nouvelle composition pharmaceutique utilisable dans le domaine des vaccins
US8302528B2 (en) 2005-10-20 2012-11-06 Conagra Foods Rdm, Inc. Cooking method and apparatus
US9211030B2 (en) 2005-10-20 2015-12-15 Conagra Foods Rdm, Inc. Steam cooking apparatus
US8850964B2 (en) 2005-10-20 2014-10-07 Conagra Foods Rdm, Inc. Cooking method and apparatus
CA2527770C (en) 2005-11-21 2014-07-22 Steven M. Parsons Food tray
US9132951B2 (en) 2005-11-23 2015-09-15 Conagra Foods Rdm, Inc. Food tray
WO2008109448A2 (en) 2007-03-02 2008-09-12 Conagra Foods Rdm, Inc. Multi-component packaging system
US20100015293A1 (en) * 2007-03-02 2010-01-21 Conagra Foods Rdm, Inc. Multi-component packaging system and apparatus
US8613249B2 (en) 2007-08-03 2013-12-24 Conagra Foods Rdm, Inc. Cooking apparatus and food product
TW200927928A (en) * 2007-09-24 2009-07-01 Nobilon Internat B V Inactivated influenza vaccine
TW201010719A (en) * 2008-08-19 2010-03-16 Wyeth Corp Immunological composition
EP2397484A1 (de) 2010-06-11 2011-12-21 Immunovo B.V. Trisaccharidderivate und ihre Verwendung als Adjuvantien
USD680426S1 (en) 2012-06-12 2013-04-23 Conagra Foods Rdm, Inc. Container
USD717162S1 (en) 2012-06-12 2014-11-11 Conagra Foods Rdm, Inc. Container
US9027825B2 (en) 2012-06-12 2015-05-12 Conagra Foods Rdm, Inc. Container assembly and foldable container system
US9492548B2 (en) * 2012-12-14 2016-11-15 Intervet Inc. Emulsion containing a non-live medicinal substance
US10647737B2 (en) 2014-07-11 2020-05-12 National Research Council Of Canada Sulfated-glycolipids as adjuvants for vaccines
DK3193923T3 (da) 2014-07-24 2019-12-09 Litevax B V Adjuvanser
FR3024981B1 (fr) * 2014-08-22 2016-09-09 Univ Montpellier 2 Sciences Et Techniques Derives polyesters d'acides gras de polyglycosides
CN104926889A (zh) * 2015-05-24 2015-09-23 广西师范学院 蔗糖硫酸酯铜银类化合物及其制作方法和用途
CN104892694A (zh) * 2015-05-24 2015-09-09 广西师范学院 蔗糖硫酸酯铜类化合物及其制作方法和用途
SG11201903890QA (en) * 2016-11-04 2019-05-30 Baxalta Inc Adeno-associated virus purification methods
CA3083576A1 (en) * 2017-09-07 2019-03-14 Hawaii Biotech, Inc. Filovirus vaccine and methods of use

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243663A (en) * 1976-06-25 1981-01-06 Ichiro Azuma Glycolipid compositions for transplanted tumor immunotherapy
JPS533514A (en) 1976-06-25 1978-01-13 Ichirou Azuma Adjuvant containing sugarlipid as effective component
WO1984004526A1 (en) † 1983-05-06 1984-11-22 Wisconsin Alumni Res Found Monosaccharide compounds having immunostimulating activity
GR860379B (en) † 1985-02-22 1986-06-11 Akzo Nv Novel disaccharide and trisaccharide derivatives of the lipid a type
US4746742A (en) † 1985-11-28 1988-05-24 Toho Yakuhin Kogyo Kabushiki Kaisha Analogs of nonreducing monosaccharide moiety of lipid A
DK316188A (da) * 1987-06-15 1988-12-16 Duphar Int Res Sulfolipopolysaccharider som stimolatorer for den ikke specifikke forsvarsmekanisme
US4912094B1 (en) † 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
DE3941061A1 (de) * 1989-12-13 1991-06-20 Henkel Kgaa Fettsaeuresorbitanestersulfate
GB9105992D0 (en) † 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccine
CA2085827C (en) * 1991-12-23 2003-10-14 Lucas A. T. Hilgers Adjuvant composition containing synthetic hydrophobic lipopolysaccharide
WO1994021292A1 (en) † 1993-03-23 1994-09-29 Smithkline Beecham Biologicals (S.A.) Vaccine compositions containing 3-o deacylated monophosphoryl lipid a
AU3191495A (en) 1994-08-09 1996-03-07 Nisshin Oil Mills, Ltd., The Peroral immunogen composition and process for producing the same
BE1008978A5 (fr) * 1994-12-27 1996-10-01 Solvay Adjuvants pour vaccins.
EP0781559B1 (de) * 1995-11-30 2007-02-07 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung
CA2211949A1 (en) * 1997-07-21 1999-01-29 David Farley Johnson Nonaqueous compositions for parenteral administration
SG102614A1 (en) † 2001-02-24 2004-03-26 Urah Resources Nigeria Ltd Solvent-free trans-acidolysis process for the preparation of edible surface-active carbohydrate fatty-acid esters

Also Published As

Publication number Publication date
US20030220270A1 (en) 2003-11-27
PT1233969E (pt) 2008-04-17
CN1433423A (zh) 2003-07-30
AU779904B2 (en) 2005-02-17
CN101108250B (zh) 2012-01-11
US20090304723A1 (en) 2009-12-10
AU2558601A (en) 2001-06-12
EP1233969A2 (de) 2002-08-28
US8052981B2 (en) 2011-11-08
CN100345592C (zh) 2007-10-31
DE60038248T3 (de) 2017-05-18
DE60038248T2 (de) 2009-03-12
WO2001040240A3 (en) 2002-02-07
EP1233969B2 (de) 2016-12-14
EP1104767A1 (de) 2001-06-06
ATE388160T1 (de) 2008-03-15
DK1233969T4 (en) 2017-03-20
ES2300285T3 (es) 2008-06-16
DK1233969T3 (da) 2008-06-09
US20050256060A1 (en) 2005-11-17
JP2003515542A (ja) 2003-05-07
CA2393072C (en) 2009-05-26
CA2393072A1 (en) 2001-06-07
JP5025869B2 (ja) 2012-09-12
US20120288528A1 (en) 2012-11-15
US8637659B2 (en) 2014-01-28
US20110305730A1 (en) 2011-12-15
CN101108250A (zh) 2008-01-23
WO2001040240A2 (en) 2001-06-07
EP1233969B1 (de) 2008-03-05

Similar Documents

Publication Publication Date Title
DE60038248D1 (de) Mono- und disaccharidderivate
MA25875A1 (fr) Nouveaux derives de l'acide aminodicarboxylique presentant des proprietes pharmaceutiques.
HUP9901652A3 (en) Use of piperidine-carboxylic acid derivatives for producing pharmaceutical compositions suitable for reducing blood glucose
ATE161836T1 (de) 4-substituierte-2-deoxy-2,3-didehydro alpha-d- neuraminsäure antivirale derivate
DE69912313D1 (de) Colchinolderivate als gefässschädigende mittel
ATE129894T1 (de) Kurzbettige, einfach ungesättigte fettsäuren enthaltende nahrungsmittel und pharmazeutische zusammensetzungen sowie deren anwendungen.
HUT49600A (en) Process for producing substituted flavonoid deriatives and salts, thereof, as well as pharmaceutical compositions comprising such compounds
BR9206858A (pt) Produção de composições de composições de suplemento alimentar
FI913863A0 (fi) Foerfarande foer framstaellning av glykosidestrar och kompositioner innehaollande glykosidestrar.
HUT64013A (en) Process for producing hiv-inhibiting phenylacetamide derivatives and pharmaceutical compositions comprising such compounds as active ingredient
IT9019829A0 (it) Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche
BG106155A (en) Novel derivatives and analogues of galanthamin
IT9021909A0 (it) Procedimento per la preparazione di epossi-eparidi prodotti ottenuti e composizioni farmaceutiche che li contengono
ID28365A (id) Turunan produk alami yang baru
FR2717081B1 (fr) Rétropeptides, anticorps dirigés contre ces derniers, et leurs utilisations pour la vaccination et le diagnostic in vitro.
BG103260A (en) The application of 1-hydroxy-2-pyridons for the treatment of seborrheic dermatitis
IT1247728B (it) Impiego di glicoproteine estratte da batteri gram-negativi per la preparazione di composizioni cosmetiche o dermatologiche e relative composizioni ottenute
EP1355914A4 (de) Herstellung von aliphatischen säureestern von kohlenhydraten
NO932044D0 (no) Funksjonaliserte, vinylazolholdige, farmasoeytiske preparater, anvendelse av disse vinylazoler for fremstilling av legemidler, vinylazoler i seg selv, saavel som fremgangsmaater for deres fremstilling
IT8720438A0 (it) Esteri di 1,4:3,6-dianidrosorbitolo-2-mononitrato e 5-mononitrato, loro procedimento di preparazione e loro composizioni farmaceutiche.
CA2075926A1 (en) Hydroquinone amino-acid esters, method of preparation, and pharmaceutical or cosmetic compositions containing them
FR2627491B1 (fr) Nouveaux derives du benzocyclohexane et du benzocycloheptane ainsi que leurs sels, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
ES2017900A4 (es) Derivados de acido tiazolidina-4-carboxilico, su preparacion y composiciones farmaceuticas conteniendolo
WO1998056759A3 (de) Neue pentaerythritderivate, deren herstellung und verwendung sowie intermediate zur synthese derselben
IT1275904B1 (it) Procedimento per la preparazione di prodotti alimentari contenenti concentrati di ortaggi e verdure

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: PROTHERICS MOLECULAR DESIGN LTD., RUNCORN, CHE, GB

8363 Opposition against the patent