IT9021909A0 - Procedimento per la preparazione di epossi-eparidi prodotti ottenuti e composizioni farmaceutiche che li contengono - Google Patents
Procedimento per la preparazione di epossi-eparidi prodotti ottenuti e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT9021909A0 IT9021909A0 IT21909A IT2190990A IT9021909A0 IT 9021909 A0 IT9021909 A0 IT 9021909A0 IT 21909 A IT21909 A IT 21909A IT 2190990 A IT2190990 A IT 2190990A IT 9021909 A0 IT9021909 A0 IT 9021909A0
- Authority
- IT
- Italy
- Prior art keywords
- eparides
- epoxy
- procedure
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000004593 Epoxy Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Epoxy Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02190990A IT1243987B (it) | 1990-10-29 | 1990-10-29 | Procedimento per la preparazione di epossi-eparidi prodotti ottenuti ecomposizioni farmaceutiche che li contengono |
DE69121666T DE69121666D1 (de) | 1990-10-29 | 1991-10-28 | Verfahren zur Herstellung von Epoxy-Hepariden; die so hergestellten Produkte und diese enthaltende pharmazeutische Zusammensetzungen |
EP91118366A EP0483733B1 (en) | 1990-10-29 | 1991-10-28 | Process for preparing epoxy-heparides, the products obtained and pharmaceutical compositions containing them |
AT91118366T ATE141929T1 (de) | 1990-10-29 | 1991-10-28 | Verfahren zur herstellung von epoxy-hepariden; die so hergestellten produkte und diese enthaltende pharmazeutische zusammensetzungen |
CA002054347A CA2054347A1 (en) | 1990-10-29 | 1991-10-28 | Process for preparing epoxy-heparides, the products obtained and pharmaceutical compositions containing them |
JP3308254A JPH04288301A (ja) | 1990-10-29 | 1991-10-29 | エポキシヘパリドの製法、その生成物及びそれらを含む医薬組成物 |
US08/146,805 US5403827A (en) | 1990-10-29 | 1993-11-02 | Process for preparing epoxy-heparides, the products obtained and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02190990A IT1243987B (it) | 1990-10-29 | 1990-10-29 | Procedimento per la preparazione di epossi-eparidi prodotti ottenuti ecomposizioni farmaceutiche che li contengono |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9021909A0 true IT9021909A0 (it) | 1990-10-29 |
IT9021909A1 IT9021909A1 (it) | 1992-04-29 |
IT1243987B IT1243987B (it) | 1994-06-28 |
Family
ID=11188614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02190990A IT1243987B (it) | 1990-10-29 | 1990-10-29 | Procedimento per la preparazione di epossi-eparidi prodotti ottenuti ecomposizioni farmaceutiche che li contengono |
Country Status (7)
Country | Link |
---|---|
US (1) | US5403827A (it) |
EP (1) | EP0483733B1 (it) |
JP (1) | JPH04288301A (it) |
AT (1) | ATE141929T1 (it) |
CA (1) | CA2054347A1 (it) |
DE (1) | DE69121666D1 (it) |
IT (1) | IT1243987B (it) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5696100A (en) * | 1992-12-22 | 1997-12-09 | Glycomed Incorporated | Method for controlling O-desulfation of heparin and compositions produced thereby |
US5296471A (en) * | 1992-12-22 | 1994-03-22 | Glycomed Incorporated | Method for controlling o-desulfation of heparin and compositions produced thereby |
US20020040008A1 (en) * | 1995-01-24 | 2002-04-04 | Wagner Denisa D. | Method for treating and preventing atherosclerosis |
US5891196A (en) * | 1997-04-16 | 1999-04-06 | Baxter International Inc. | Method for actively binding heparin to crosslinked biological tissues |
AU2003225724A1 (en) | 2002-03-11 | 2003-09-29 | Momenta Pharmaceuticals, Inc. | Analysis of sulfated polysaccharides |
US9139876B1 (en) | 2007-05-03 | 2015-09-22 | Momenta Pharmacueticals, Inc. | Method of analyzing a preparation of a low molecular weight heparin |
US8592393B2 (en) | 2007-11-02 | 2013-11-26 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
EP2205642B1 (en) * | 2007-11-02 | 2016-01-27 | Momenta Pharmaceuticals, Inc. | Non-anticoagulant polysaccharide compositions |
US8569262B2 (en) | 2007-11-02 | 2013-10-29 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
ES2817779T3 (es) * | 2010-01-19 | 2021-04-08 | Momenta Pharmaceuticals Inc | Evaluación de preparaciones de heparina |
EP2558506B1 (en) | 2010-04-16 | 2019-06-26 | Momenta Pharmaceuticals, Inc. | Tissue targeting |
CN103096870B (zh) | 2010-06-17 | 2017-04-19 | 动量制药公司 | 调节毛发生长的方法和组合物 |
US9068957B2 (en) | 2011-02-21 | 2015-06-30 | Momenta Pharmaceuticals, Inc. | Evaluating heparin preparations |
EP3003324A4 (en) | 2013-05-28 | 2017-01-25 | Momenta Pharmaceuticals, Inc. | Pharmaceutical compositions |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3179566A (en) * | 1963-05-16 | 1965-04-20 | Canada Packers Ltd | Purification of heparin |
FR2538404B1 (it) * | 1982-12-28 | 1985-08-23 | Anic Spa | |
IT1195497B (it) * | 1983-03-08 | 1988-10-19 | Opocrin Spa | Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina |
DE3422518A1 (de) * | 1984-06-16 | 1985-12-19 | B. Braun Melsungen Ag, 3508 Melsungen | Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen |
IT1214609B (it) * | 1985-05-17 | 1990-01-18 | Opocrin Spa | Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono. |
IT1234508B (it) * | 1988-06-10 | 1992-05-19 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
US4981955A (en) * | 1988-06-28 | 1991-01-01 | Lopez Lorenzo L | Depolymerization method of heparin |
-
1990
- 1990-10-29 IT IT02190990A patent/IT1243987B/it active IP Right Grant
-
1991
- 1991-10-28 DE DE69121666T patent/DE69121666D1/de not_active Expired - Lifetime
- 1991-10-28 AT AT91118366T patent/ATE141929T1/de not_active IP Right Cessation
- 1991-10-28 EP EP91118366A patent/EP0483733B1/en not_active Expired - Lifetime
- 1991-10-28 CA CA002054347A patent/CA2054347A1/en not_active Abandoned
- 1991-10-29 JP JP3308254A patent/JPH04288301A/ja active Pending
-
1993
- 1993-11-02 US US08/146,805 patent/US5403827A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2054347A1 (en) | 1992-04-30 |
ATE141929T1 (de) | 1996-09-15 |
IT9021909A1 (it) | 1992-04-29 |
EP0483733A1 (en) | 1992-05-06 |
US5403827A (en) | 1995-04-04 |
JPH04288301A (ja) | 1992-10-13 |
IT1243987B (it) | 1994-06-28 |
EP0483733B1 (en) | 1996-08-28 |
DE69121666D1 (de) | 1996-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961015 |