DE60037584D1 - Auf microarrays basierende substraktive hybridisierung - Google Patents

Auf microarrays basierende substraktive hybridisierung

Info

Publication number
DE60037584D1
DE60037584D1 DE60037584T DE60037584T DE60037584D1 DE 60037584 D1 DE60037584 D1 DE 60037584D1 DE 60037584 T DE60037584 T DE 60037584T DE 60037584 T DE60037584 T DE 60037584T DE 60037584 D1 DE60037584 D1 DE 60037584D1
Authority
DE
Germany
Prior art keywords
identification
removal
nucleic acids
present
library
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60037584T
Other languages
English (en)
Other versions
DE60037584T2 (de
Inventor
Steven Perrin
Katherine Call
Timothy Connolly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Application granted granted Critical
Publication of DE60037584D1 publication Critical patent/DE60037584D1/de
Publication of DE60037584T2 publication Critical patent/DE60037584T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Ceramic Products (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60037584T 1999-05-19 2000-05-19 Auf microarrays basierende substraktive hybridisierung Expired - Lifetime DE60037584T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US314698 1981-10-26
US09/314,698 US6638717B2 (en) 1999-05-19 1999-05-19 Microarray-based subtractive hybridzation
PCT/US2000/013789 WO2000070098A1 (en) 1999-05-19 2000-05-19 Microarray-based subtractive hybridization

Publications (2)

Publication Number Publication Date
DE60037584D1 true DE60037584D1 (de) 2008-02-07
DE60037584T2 DE60037584T2 (de) 2009-01-08

Family

ID=23221053

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037584T Expired - Lifetime DE60037584T2 (de) 1999-05-19 2000-05-19 Auf microarrays basierende substraktive hybridisierung

Country Status (18)

Country Link
US (1) US6638717B2 (de)
EP (1) EP1185699B1 (de)
JP (1) JP4714883B2 (de)
KR (1) KR100733930B1 (de)
AT (1) ATE382097T1 (de)
AU (1) AU779901B2 (de)
BR (1) BR0011297A (de)
CA (1) CA2372698C (de)
CY (1) CY1107428T1 (de)
DE (1) DE60037584T2 (de)
DK (1) DK1185699T3 (de)
ES (1) ES2296623T3 (de)
IL (2) IL146547A0 (de)
MX (1) MXPA01011730A (de)
NO (1) NO330813B1 (de)
PT (1) PT1185699E (de)
WO (1) WO2000070098A1 (de)
ZA (1) ZA200109609B (de)

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US20050272056A1 (en) * 1996-11-13 2005-12-08 Deiss Louis P Gene identification method
US20020142341A1 (en) * 2001-03-28 2002-10-03 Makoto Kameyama Method and apparatus for producing probe carrier
US20040110153A1 (en) * 2002-12-10 2004-06-10 Affymetrix, Inc. Compleixity management of genomic DNA by semi-specific amplification
JP4182338B2 (ja) * 2003-03-06 2008-11-19 信越化学工業株式会社 熱硬化性パーフルオロポリエーテル系ゴム組成物及びゴム製品
US7300755B1 (en) * 2003-05-12 2007-11-27 Fred Hutchinson Cancer Research Center Methods for haplotyping genomic DNA
US20050075712A1 (en) 2003-10-06 2005-04-07 Brian Biancucci Minimally invasive valve replacement system
EP2290071B1 (de) 2004-05-28 2014-12-31 Asuragen, Inc. Verfahren und Zusammensetzungen mit MicroRNA
EP2281888B1 (de) 2004-11-12 2015-01-07 Asuragen, Inc. Verfahren und Zusammensetzungen, die miRNA und miRNA-inhibitorischen Molekülen verbunden sind
EP2145001A2 (de) 2006-09-19 2010-01-20 Asuragen, Inc. Von mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p regulierte gene und stoffwechselwege als ziele für einen therapeutischen eingriff
AU2007299828C1 (en) 2006-09-19 2014-07-17 Interpace Diagnostics, Llc MicroRNAs differentially expressed in pancreatic diseases and uses thereof
GB0618514D0 (en) * 2006-09-20 2006-11-01 Univ Nottingham Trent Method of detecting interactions on a microarray using nuclear magnetic resonance
US8716190B2 (en) 2007-09-14 2014-05-06 Affymetrix, Inc. Amplification and analysis of selected targets on solid supports
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US8258111B2 (en) 2008-05-08 2012-09-04 The Johns Hopkins University Compositions and methods related to miRNA modulation of neovascularization or angiogenesis
JP5221248B2 (ja) * 2008-08-26 2013-06-26 株式会社日立ハイテクノロジーズ 高発現遺伝子由来のｃＤＮＡクローンの含有率を低減させたｃＤＮＡライブラリーの作製方法
US20100331204A1 (en) * 2009-02-13 2010-12-30 Jeff Jeddeloh Methods and systems for enrichment of target genomic sequences
US20110059453A1 (en) * 2009-08-23 2011-03-10 Affymetrix, Inc. Poly(A) Tail Length Measurement by PCR
EP3214174B1 (de) 2010-03-04 2019-10-16 InteRNA Technologies B.V. Mirna-molekül, das über seine quelle definiert ist, und seine diagnostischen und therapeutischen verwendungen bei mit emt assoziierten krankheiten
AU2011274619B2 (en) 2010-07-06 2016-11-10 Interna Technologies Bv miRNA and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated BRAF pathway
EP2640851A2 (de) 2010-11-17 2013-09-25 Asuragen, Inc. Mirna als biomarker zur unterscheidung zwischen benignen und malignen neoplasien der schilddrüse
EP2474617A1 (de) 2011-01-11 2012-07-11 InteRNA Technologies BV MIR zur Behandlung von Neoangiogenese
CA2828532A1 (en) 2011-02-28 2012-11-22 University Of Iowa Research Foundation Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender
EP2705153A1 (de) 2011-05-02 2014-03-12 Pioneer Hi-Bred International, Inc. Screening von bakterieller mrna für die entdeckung neuer pestizid-kodierender nukleinsäuremoleküle
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
US20130157884A1 (en) 2011-10-26 2013-06-20 Asuragen, Inc. Methods and compositions involving mirna expression levels for distinguishing pancreatic cysts
EP2771487A1 (de) 2011-10-27 2014-09-03 Asuragen, INC. Mirnas als diagnostische biomarker zur unterscheidung gutartiger von bösartigen tumoren in der schilddrüse
WO2014007623A1 (en) 2012-07-03 2014-01-09 Interna Technologies B.V. Diagnostic portfolio and its uses
US20140100124A1 (en) 2012-10-04 2014-04-10 Asuragen, Inc. Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions
WO2014144666A2 (en) 2013-03-15 2014-09-18 The University Of Chicago Methods and compositions related to t-cell activity
CA2907377A1 (en) 2013-03-15 2014-09-18 Baylor Research Institute Tissue and blood-based mirna biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer
EP2971149B1 (de) 2013-03-15 2018-05-09 Baylor Research Institute Marker für mit colitis ulcerosa (uc) assoziierten kolorektalen neoplasien
KR101516976B1 (ko) * 2013-10-30 2015-05-04 에스케이텔레콤 주식회사 표적 염기 서열 해독에서의 바이어스 제거 방법
CN111566212A (zh) 2017-11-03 2020-08-21 因特尔纳技术有限公司 miRNA分子，等同物，安塔够妙或其来源用于治疗和/或诊断与神经元缺陷相关的病症和/或疾病或用于神经元生成和/或再生
CN113924085A (zh) 2019-04-12 2022-01-11 加利福尼亚大学董事会 用于增加肌肉量和氧化代谢的组合物和方法
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders

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US5821058A (en) 1984-01-16 1998-10-13 California Institute Of Technology Automated DNA sequencing technique
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5591575A (en) 1993-04-07 1997-01-07 Amersham International Plc Subtraction hybridization employing aziridinylbenoquinone cross-linking agents
US5482845A (en) 1993-09-24 1996-01-09 The Trustees Of Columbia University In The City Of New York Method for construction of normalized cDNA libraries
US5690894A (en) * 1995-05-23 1997-11-25 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
US5728529A (en) 1995-06-23 1998-03-17 Baylor College Of Medicine Alternative dye-labeled ribonucleotides, deoxyribonucleotides, and dideoxyribonucleotides for automated DNA analysis
US5851772A (en) 1996-01-29 1998-12-22 University Of Chicago Microchip method for the enrichment of specific DNA sequences
US5712127A (en) 1996-04-29 1998-01-27 Genescape Inc. Subtractive amplification
US5827658A (en) 1996-08-09 1998-10-27 The United States Of America As Reprsented By The Department Of Health And Human Services Isolation of amplified genes via cDNA subtractive hybridization
GB9618050D0 (en) 1996-08-29 1996-10-09 Cancer Res Campaign Tech Global amplification of nucleic acids
US5846721A (en) 1996-09-19 1998-12-08 The Trustees Of Columbia University In The City Of New York Efficient and simpler method to construct normalized cDNA libraries with improved representations of full-length cDNAs
US5953727A (en) * 1996-10-10 1999-09-14 Incyte Pharmaceuticals, Inc. Project-based full-length biomolecular sequence database
CA2284481A1 (en) 1997-03-24 1998-10-01 Smithkline Beecham Corporation Method of producing a subtraction library
US6399334B1 (en) 1997-09-24 2002-06-04 Invitrogen Corporation Normalized nucleic acid libraries and methods of production thereof
EP1032705B1 (de) 1997-10-30 2011-12-14 Cold Spring Harbor Laboratory Sondenanordnungen und deren verwendungen für verfahren zur dns-unterscheidung
US5882874A (en) 1998-02-27 1999-03-16 The Trustees Of Columbia University In The City Of New York Reciprocal subtraction differential display

Also Published As

Publication number Publication date
ES2296623T3 (es) 2008-05-01
NO330813B1 (no) 2011-07-25
US20020051970A1 (en) 2002-05-02
ATE382097T1 (de) 2008-01-15
CA2372698C (en) 2010-04-27
JP2002543856A (ja) 2002-12-24
CY1107428T1 (el) 2012-12-19
DK1185699T3 (da) 2008-04-28
ZA200109609B (en) 2003-04-30
NO20015635D0 (no) 2001-11-19
IL146547A (en) 2008-04-13
WO2000070098A1 (en) 2000-11-23
PT1185699E (pt) 2008-02-26
EP1185699A1 (de) 2002-03-13
MXPA01011730A (es) 2002-04-24
DE60037584T2 (de) 2009-01-08
US6638717B2 (en) 2003-10-28
IL146547A0 (en) 2002-07-25
CA2372698A1 (en) 2000-11-23
AU5145500A (en) 2000-12-05
KR100733930B1 (ko) 2007-07-03
NO20015635L (no) 2002-01-15
EP1185699B1 (de) 2007-12-26
JP4714883B2 (ja) 2011-06-29
KR20020008190A (ko) 2002-01-29
BR0011297A (pt) 2002-02-26
AU779901B2 (en) 2005-02-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS HOLDINGS INC., GREENVILLE, DEL., US

8327 Change in the person/name/address of the patent owner

Owner name: AVENTISUB II INC., GREENVILLE, DEL., US