DE60035515D1 - Hohe zytokinproduktion mit verbesserte zelllebensfähigkeit - Google Patents

Hohe zytokinproduktion mit verbesserte zelllebensfähigkeit

Info

Publication number
DE60035515D1
DE60035515D1 DE60035515T DE60035515T DE60035515D1 DE 60035515 D1 DE60035515 D1 DE 60035515D1 DE 60035515 T DE60035515 T DE 60035515T DE 60035515 T DE60035515 T DE 60035515T DE 60035515 D1 DE60035515 D1 DE 60035515D1
Authority
DE
Germany
Prior art keywords
improved cell
cell life
cytokin
production
cytokin production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60035515T
Other languages
English (en)
Other versions
DE60035515T2 (de
Inventor
Allan S Lau
Laura Browning
Michael C Kiefer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetrol Biotherapeutics Inc
Original Assignee
Genetrol Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetrol Biotherapeutics Inc filed Critical Genetrol Biotherapeutics Inc
Application granted granted Critical
Publication of DE60035515D1 publication Critical patent/DE60035515D1/de
Publication of DE60035515T2 publication Critical patent/DE60035515T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60035515T 1999-09-08 2000-09-08 Hohe zytokinproduktion mit verbesserter zelllebensfähigkeit Expired - Fee Related DE60035515T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15285499P 1999-09-08 1999-09-08
US152854P 1999-09-08
PCT/US2000/024657 WO2001018185A1 (en) 1999-09-08 2000-09-08 High level cytokine production with enhanced cell viability

Publications (2)

Publication Number Publication Date
DE60035515D1 true DE60035515D1 (de) 2007-08-23
DE60035515T2 DE60035515T2 (de) 2008-04-17

Family

ID=22544735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035515T Expired - Fee Related DE60035515T2 (de) 1999-09-08 2000-09-08 Hohe zytokinproduktion mit verbesserter zelllebensfähigkeit

Country Status (8)

Country Link
EP (1) EP1214399B1 (de)
JP (1) JP2003509025A (de)
AT (1) ATE366803T1 (de)
AU (1) AU7126000A (de)
CA (1) CA2383563A1 (de)
DE (1) DE60035515T2 (de)
HK (1) HK1048135A1 (de)
WO (1) WO2001018185A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010031859A1 (en) * 1999-09-08 2001-10-18 Lau Allan S. High level cytokine production with enhanced cell viability
DE60025015T2 (de) 1999-09-27 2006-08-03 Genentech Inc., San Francisco Verfahren zur herstellung von rekombinanten proteinen mittels inhibitoren von apoptose
EP1318834A2 (de) * 2000-09-12 2003-06-18 Genetrol Biotherapeutics, Inc. Zusammensetzung, die eine mischung von menschlichen zytokinen enthält, sowie verfahren für ihre herstellung
US6864061B2 (en) 2000-09-14 2005-03-08 Genetrol Biotherapeutics, Inc. Method for screening compounds for anti-inflammatory activity
JP4849408B2 (ja) 2004-03-01 2012-01-11 財団法人北九州産業学術推進機構 タンパク質産生新規ヒト細胞株、新規ヒト細胞株の選択方法、新規ヒト細胞株の使用、それらからのタンパク質産生方法及び精製方法、及び新規ヒト細胞株を利用した薬学組成物
WO2007067032A1 (en) 2005-12-09 2007-06-14 Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam Means and methods for influencing the stability of cells
NZ600075A (en) 2005-12-09 2013-12-20 Amc Amsterdam Means and methods for influencing the stability of antibody producing cells
CA2768207C (en) 2009-07-15 2019-12-03 Aimm Therapeutics B.V. Means and methods for producing high affinity antibodies
PL2646466T3 (pl) 2010-12-02 2017-09-29 Aimm Therapeutics B.V. Środki i sposoby do wytwarzania przeciwciał o wysokim powinowactwie
DK3099709T3 (da) 2014-01-31 2020-02-03 Aimm Therapeutics Bv Midler og fremgangsmåder til fremstilling af stabile antistoffer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840565A (en) * 1995-08-22 1998-11-24 The Regents Of The University Of California Methods for enhancing the production of viral vaccines in PKR-deficient cell culture
AU3583797A (en) * 1996-06-28 1998-01-21 Regents Of The University Of California, The Enhancement of cancer cell death

Also Published As

Publication number Publication date
WO2001018185A1 (en) 2001-03-15
HK1048135A1 (zh) 2003-03-21
AU7126000A (en) 2001-04-10
JP2003509025A (ja) 2003-03-11
ATE366803T1 (de) 2007-08-15
EP1214399B1 (de) 2007-07-11
CA2383563A1 (en) 2001-03-15
DE60035515T2 (de) 2008-04-17
EP1214399A1 (de) 2002-06-19

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: GENETROL BIOTHERAPEUTICS, INC., OAKLAND, CALIF, US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8370 Indication related to discontinuation of the patent is to be deleted
8339 Ceased/non-payment of the annual fee