DE60035293D1 - Aufgebrachte dünne filme und ihr gebrauch in nachweis, anheftung und biomedizinischen anwendungen - Google Patents

Aufgebrachte dünne filme und ihr gebrauch in nachweis, anheftung und biomedizinischen anwendungen

Info

Publication number
DE60035293D1
DE60035293D1 DE60035293T DE60035293T DE60035293D1 DE 60035293 D1 DE60035293 D1 DE 60035293D1 DE 60035293 T DE60035293 T DE 60035293T DE 60035293 T DE60035293 T DE 60035293T DE 60035293 D1 DE60035293 D1 DE 60035293D1
Authority
DE
Germany
Prior art keywords
thin films
proof
mounting
media
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60035293T
Other languages
English (en)
Inventor
Stephen J Fonash
Sanghoon Bae
Daniel J Hayes
Joseph Cuiffi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penn State Research Foundation
Original Assignee
Penn State Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/580,105 external-priority patent/US6399177B1/en
Application filed by Penn State Research Foundation filed Critical Penn State Research Foundation
Application granted granted Critical
Publication of DE60035293D1 publication Critical patent/DE60035293D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C16/00Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
    • C23C16/44Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
    • C23C16/50Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
    • C23C16/511Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using microwave discharges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81CPROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00349Creating layers of material on a substrate
    • B81C1/0038Processes for creating layers of materials not provided for in groups B81C1/00357 - B81C1/00373
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C16/00Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
    • C23C16/22Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of inorganic material, other than metallic material
    • C23C16/24Deposition of silicon only
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • H01J49/0418Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/02Sensors
    • B81B2201/0214Biosensors; Chemical sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81CPROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2201/00Manufacture or treatment of microstructural devices or systems
    • B81C2201/01Manufacture or treatment of microstructural devices or systems in or on a substrate
    • B81C2201/0174Manufacture or treatment of microstructural devices or systems in or on a substrate for making multi-layered devices, film deposition or growing
    • B81C2201/0176Chemical vapour Deposition
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/119163Automated chemical analysis with aspirator of claimed structure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Metallurgy (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Electrochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Laminated Bodies (AREA)
  • Electrostatic, Electromagnetic, Magneto- Strictive, And Variable-Resistance Transducers (AREA)
DE60035293T 1999-12-20 2000-12-19 Aufgebrachte dünne filme und ihr gebrauch in nachweis, anheftung und biomedizinischen anwendungen Expired - Lifetime DE60035293D1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US17284099P 1999-12-20 1999-12-20
US20193700P 2000-05-05 2000-05-05
US20193600P 2000-05-05 2000-05-05
US09/580,105 US6399177B1 (en) 1999-06-03 2000-05-30 Deposited thin film void-column network materials
US23147400P 2000-09-08 2000-09-08
PCT/US2000/034411 WO2001046458A1 (en) 1999-12-20 2000-12-19 Deposited thin films and their use in detection, attachment, and bio-medical applications

Publications (1)

Publication Number Publication Date
DE60035293D1 true DE60035293D1 (de) 2007-08-02

Family

ID=27538878

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035293T Expired - Lifetime DE60035293D1 (de) 1999-12-20 2000-12-19 Aufgebrachte dünne filme und ihr gebrauch in nachweis, anheftung und biomedizinischen anwendungen

Country Status (9)

Country Link
US (1) US6794196B2 (de)
EP (1) EP1254249B1 (de)
JP (1) JP2005500507A (de)
CN (1) CN1238721C (de)
AT (1) ATE365223T1 (de)
AU (1) AU2277001A (de)
CA (1) CA2394942A1 (de)
DE (1) DE60035293D1 (de)
WO (1) WO2001046458A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122790B2 (en) * 2000-05-30 2006-10-17 The Penn State Research Foundation Matrix-free desorption ionization mass spectrometry using tailored morphology layer devices
WO2002004935A1 (fr) * 2000-07-06 2002-01-17 Asahi Kasei Kabushiki Kaisha Détecteur de molécules
WO2002093170A1 (en) * 2001-05-14 2002-11-21 The Penn State Research Foundation Matrix-free desorption ionization mass spectrometry using tailored morphology layer devices
US7366704B2 (en) * 2001-06-28 2008-04-29 Waters Investments, Limited System and method for deconvoluting the effect of topography on scanning probe microscopy measurements
AU2003202872A1 (en) * 2002-01-04 2003-07-24 Nuccon Technologies Inc. Preparation of nano-sized crystals
US7229847B2 (en) * 2002-03-15 2007-06-12 Lucent Technologies Inc. Forming electrical contacts to a molecular layer
US20030235921A1 (en) * 2002-06-24 2003-12-25 Lucent Technologies Inc. Forming electrical contacts to a molecular layer
US7687256B2 (en) * 2002-04-11 2010-03-30 Spire Corporation Surface activated biochip
US8294025B2 (en) * 2002-06-08 2012-10-23 Solarity, Llc Lateral collection photovoltaics
US7105809B2 (en) 2002-11-18 2006-09-12 3M Innovative Properties Company Microstructured polymeric substrate
DE112004000253T5 (de) * 2003-02-10 2006-02-02 Waters Investments Ltd., New Castle Adsorption, Detektion und Identifikation von Komponenten der Umgebungsluft mit Desorption/Ionisation auf Silizium und Massenspektrometrie (DIOS-MS)
US8274643B2 (en) * 2003-03-05 2012-09-25 The Regents Of The University Of California Porous nanostructures and methods involving the same
US7579077B2 (en) * 2003-05-05 2009-08-25 Nanosys, Inc. Nanofiber surfaces for use in enhanced surface area applications
US7972616B2 (en) * 2003-04-17 2011-07-05 Nanosys, Inc. Medical device applications of nanostructured surfaces
TWI427709B (zh) * 2003-05-05 2014-02-21 Nanosys Inc 用於增加表面面積之應用的奈米纖維表面
US7803574B2 (en) 2003-05-05 2010-09-28 Nanosys, Inc. Medical device applications of nanostructured surfaces
CN1304843C (zh) * 2003-07-02 2007-03-14 许洋 用于生物样品分析的蛋白指纹法
US20070092964A1 (en) * 2003-09-03 2007-04-26 Zymoyx, Inc. Ion detection using a pillar chip
US20050094855A1 (en) * 2003-10-29 2005-05-05 Proano Cesar H. Fingerprint imaging using a flat panel detector
WO2005104180A2 (en) * 2004-04-27 2005-11-03 Koninklijke Philips Electronics N.V. Use of a composite or composition of diamond and other material for analysis of analytes
US6958480B1 (en) 2004-06-25 2005-10-25 The Regents Of The University Of California Sample desorption/ionization from mesoporous silica
US7391018B2 (en) * 2004-09-17 2008-06-24 Nanosys, Inc. Nanostructured thin films and their uses
US8084400B2 (en) * 2005-10-11 2011-12-27 Intermolecular, Inc. Methods for discretized processing and process sequence integration of regions of a substrate
US8329202B2 (en) 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
JP4761144B2 (ja) * 2005-04-28 2011-08-31 独立行政法人産業技術総合研究所 質量分析用イオン化基板及び質量分析装置
US7544574B2 (en) * 2005-10-11 2009-06-09 Intermolecular, Inc. Methods for discretized processing of regions of a substrate
US7827042B2 (en) 2005-11-30 2010-11-02 The Invention Science Fund I, Inc Methods and systems related to transmission of nutraceutical associated information
US7974856B2 (en) 2005-11-30 2011-07-05 The Invention Science Fund I, Llc Computational systems and methods related to nutraceuticals
US7927787B2 (en) 2006-06-28 2011-04-19 The Invention Science Fund I, Llc Methods and systems for analysis of nutraceutical associated components
US20080241000A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for pathogen detection
US20080210748A1 (en) 2005-11-30 2008-09-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware, Systems and methods for receiving pathogen related information and responding
US20080241909A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for pathogen detection
US10296720B2 (en) 2005-11-30 2019-05-21 Gearbox Llc Computational systems and methods related to nutraceuticals
US8000981B2 (en) 2005-11-30 2011-08-16 The Invention Science Fund I, Llc Methods and systems related to receiving nutraceutical associated information
US8340944B2 (en) 2005-11-30 2012-12-25 The Invention Science Fund I, Llc Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US8297028B2 (en) 2006-06-14 2012-10-30 The Invention Science Fund I, Llc Individualized pharmaceutical selection and packaging
US20080241910A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for pathogen detection
CN101351868B (zh) * 2005-12-29 2013-03-13 3M创新有限公司 使用涂覆工艺雾化材料的方法
US20070224697A1 (en) * 2006-03-24 2007-09-27 Bruker Daltonics, Inc. Means and method for analyzing samples by mass spectrometry
DE102006016324A1 (de) * 2006-04-06 2007-10-25 Wacker Chemie Ag Vorrichtung und Verfahren zum flexiblen Klassieren von polykristallinen Silicium-Bruchstücken
WO2007124128A2 (en) * 2006-04-20 2007-11-01 Liquidia Technologies, Inc. Biological vessel flow control devices and methods
US8084734B2 (en) * 2006-05-26 2011-12-27 The George Washington University Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays
US7863603B1 (en) * 2006-07-24 2011-01-04 The Board Of Trustees Of The Leland Stanford Junior University Cross-linked organic thin-film dielectrics
US20080128608A1 (en) * 2006-11-06 2008-06-05 The Scripps Research Institute Nanostructure-initiator mass spectrometry
US10001496B2 (en) 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
US8617903B2 (en) 2007-01-29 2013-12-31 The Invention Science Fund I, Llc Methods for allergen detection
US20080181821A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for allergen detection
US20090050569A1 (en) * 2007-01-29 2009-02-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US20090227005A1 (en) * 2007-03-27 2009-09-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
EP2171763A2 (de) * 2007-06-26 2010-04-07 Solarity, Inc. Lateralsammlungs-fotovoltaiken
US20090130746A1 (en) * 2007-10-25 2009-05-21 Canon U.S. Life Sciences, Inc. Microchannel surface coating
US8319002B2 (en) * 2007-12-06 2012-11-27 Nanosys, Inc. Nanostructure-enhanced platelet binding and hemostatic structures
WO2009073854A1 (en) 2007-12-06 2009-06-11 Nanosys, Inc. Resorbable nanoenhanced hemostatic structures and bandage materials
US8424370B2 (en) 2009-01-16 2013-04-23 Matrix Sensors, Inc. Liquid analysis using capacitative micromachined ultrasound transducers
US8110796B2 (en) 2009-01-17 2012-02-07 The George Washington University Nanophotonic production, modulation and switching of ions by silicon microcolumn arrays
CN102378911A (zh) * 2009-02-04 2012-03-14 莱泽尔诊断公司 用于分离和分析流体中的组分的装置和方法
US9490113B2 (en) * 2009-04-07 2016-11-08 The George Washington University Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry
KR101802541B1 (ko) 2010-02-23 2017-11-30 크리스토퍼 고든 앳우드 생물학적 관련 분자 및 이들의 상호작용 특징을 검출하는 방법
US8963080B2 (en) * 2011-01-22 2015-02-24 Michael Charles Nyman Substrate compositions and methods of use thereof
US10877041B2 (en) * 2014-05-05 2020-12-29 Nicolas H. VOELCKER Methods of detecting biological prints, fluids or analytes therein using porous semiconductor substrates
CN104267027A (zh) * 2014-10-17 2015-01-07 北京理工大学 一种利用可显色印迹胶体薄膜检测目标物的方法
CA2972500C (en) * 2014-12-31 2023-09-12 Fluidigm Canada Inc. Structured biological samples for analysis by mass cytometry
IL259837B2 (en) * 2015-12-08 2023-03-01 Berkeley Lights Inc Microfluidic devices and kits and their uses
DE102016208970A1 (de) * 2016-05-24 2017-11-30 Robert Bosch Gmbh Verfahren zum Herstellen einer Elektromigration-resistenten kristallinen Übergangsmetall-Silizidschicht, entsprechende Schichtenfolge und Mikro-Heizer
US10761012B1 (en) * 2017-06-05 2020-09-01 Michael C. Solazzi Computer-implemented method of thin-film selection for spectroscopy
BE1025524B1 (nl) * 2017-09-04 2019-04-05 PharmaFluidics N.V. Chemische reactoren
US11948787B2 (en) 2018-02-09 2024-04-02 Hamamatsu Photonics K.K. Sample support, and manufacturing method of sample support
CN110672667B (zh) * 2019-10-17 2021-02-26 北京航空航天大学 一种用于测量等离子体沉积的动态压阻探针
CN112525902B (zh) * 2020-11-13 2022-11-08 昆明理工大学 一种合金抗氧化性能的高通量测试方法
US11867562B2 (en) * 2022-01-25 2024-01-09 Visera Technologies Company Limited Optical devices
JP2023119234A (ja) * 2022-02-16 2023-08-28 浜松ホトニクス株式会社 試料支持体、イオン化法、及び質量分析方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676188A (en) * 1967-08-23 1972-07-11 Trw Inc Method for preparing sensors for detecting reducing vapors
US4384957A (en) * 1980-09-08 1983-05-24 Amf Incorporated Molecular separation column and use thereof
EP0494896B1 (de) * 1989-10-04 1994-07-06 E.I. Du Pont De Nemours And Company Bestimmungsverfahren für biologische zielkomplexe auf der oberfläche eines biosensors
US5238729A (en) * 1991-04-05 1993-08-24 Minnesota Mining And Manufacturing Company Sensors based on nanosstructured composite films
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
DK0700521T3 (da) * 1993-05-28 2003-09-29 Baylor College Medicine Fremgangsmåde og massespektrometer til desorption og ionisering af analysander
US5552272A (en) * 1993-06-10 1996-09-03 Biostar, Inc. Detection of an analyte by fluorescence using a thin film optical device
US5437999A (en) * 1994-02-22 1995-08-01 Boehringer Mannheim Corporation Electrochemical sensor
US5776674A (en) * 1995-06-05 1998-07-07 Seq, Ltd Chemical biochemical and biological processing in thin films
US5589136A (en) * 1995-06-20 1996-12-31 Regents Of The University Of California Silicon-based sleeve devices for chemical reactions
GB9518429D0 (en) * 1995-09-08 1995-11-08 Pharmacia Biosensor A rapid method for providing kinetic and structural data in molecular interaction analysis
US5705813A (en) * 1995-11-01 1998-01-06 Hewlett-Packard Company Integrated planar liquid handling system for maldi-TOF MS
US5716825A (en) * 1995-11-01 1998-02-10 Hewlett Packard Company Integrated nucleic acid analysis system for MALDI-TOF MS
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US5854486A (en) * 1996-12-27 1998-12-29 R. T. Hodgson Method and apparatus for MALDI mass spectrometry
US6051321A (en) * 1997-10-24 2000-04-18 Quester Technology, Inc. Low dielectric constant materials and method
EP1166329A4 (de) * 1999-03-09 2005-03-23 Scripps Research Inst Verfahren und vorrichtung zur desorption/ionisation von porösen, lichtabsorbierende holbleitern
CN1160186C (zh) * 1999-06-03 2004-08-04 宾夕法尼亚州研究基金会 纳米尺度的组合物、复合结构、其制造和应用

Also Published As

Publication number Publication date
CA2394942A1 (en) 2001-06-28
JP2005500507A (ja) 2005-01-06
US20020048531A1 (en) 2002-04-25
US6794196B2 (en) 2004-09-21
EP1254249B1 (de) 2007-06-20
EP1254249A4 (de) 2005-07-06
CN1413261A (zh) 2003-04-23
AU2277001A (en) 2001-07-03
EP1254249A1 (de) 2002-11-06
CN1238721C (zh) 2006-01-25
WO2001046458A1 (en) 2001-06-28
ATE365223T1 (de) 2007-07-15

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