DE60034476T2 - Topische nasenbehandlung mit desloratadin und mometason furoat - Google Patents

Topische nasenbehandlung mit desloratadin und mometason furoat Download PDF

Info

Publication number
DE60034476T2
DE60034476T2 DE60034476T DE60034476T DE60034476T2 DE 60034476 T2 DE60034476 T2 DE 60034476T2 DE 60034476 T DE60034476 T DE 60034476T DE 60034476 T DE60034476 T DE 60034476T DE 60034476 T2 DE60034476 T2 DE 60034476T2
Authority
DE
Germany
Prior art keywords
desloratadine
mometasone furoate
topical
nasal
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60034476T
Other languages
German (de)
English (en)
Other versions
DE60034476D1 (de
Inventor
Stephen J. Mendham ANDRZEJEWSKI
William West Paterson KREUTNER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE60034476D1 publication Critical patent/DE60034476D1/de
Application granted granted Critical
Publication of DE60034476T2 publication Critical patent/DE60034476T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60034476T 1999-10-08 2000-10-05 Topische nasenbehandlung mit desloratadin und mometason furoat Expired - Lifetime DE60034476T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41508399A 1999-10-08 1999-10-08
US415083 1999-10-08
PCT/US2000/027463 WO2001026658A2 (en) 1999-10-08 2000-10-05 Topical nasal treatment using desloratadine

Publications (2)

Publication Number Publication Date
DE60034476D1 DE60034476D1 (de) 2007-05-31
DE60034476T2 true DE60034476T2 (de) 2008-01-03

Family

ID=23644317

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60034476T Expired - Lifetime DE60034476T2 (de) 1999-10-08 2000-10-05 Topische nasenbehandlung mit desloratadin und mometason furoat

Country Status (9)

Country Link
EP (1) EP1227812B1 (cg-RX-API-DMAC7.html)
JP (3) JP2003511417A (cg-RX-API-DMAC7.html)
AR (1) AR025964A1 (cg-RX-API-DMAC7.html)
AT (1) ATE359784T1 (cg-RX-API-DMAC7.html)
AU (1) AU7859800A (cg-RX-API-DMAC7.html)
CA (1) CA2383970A1 (cg-RX-API-DMAC7.html)
DE (1) DE60034476T2 (cg-RX-API-DMAC7.html)
ES (1) ES2284531T3 (cg-RX-API-DMAC7.html)
WO (1) WO2001026658A2 (cg-RX-API-DMAC7.html)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003264859A1 (en) * 2001-12-21 2003-12-19 Sampad Bhattacharya Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor
TR200201343A2 (tr) * 2002-05-17 2003-12-22 Orva İlaç Sanayi̇ Ve Ti̇caret A. Ş. Kortikosteroid ve antiseptik içeren farmasötik bileşim
JP2006508138A (ja) * 2002-11-12 2006-03-09 アルコン，インコーポレイテッド アレルギー性鼻炎を処置するための抗アレルギー剤およびステロイドの使用
WO2004082525A2 (en) 2003-03-14 2004-09-30 Sinexus, Inc. Sinus delivery of sustained release therapeutics
WO2004082589A2 (en) * 2003-03-20 2004-09-30 Ranbaxy Laboratories Limited Nasally administrable, bioavailable pharmaceutical composition of loratadine
US20050192261A1 (en) * 2003-09-15 2005-09-01 Jost-Price Edward R. Methods and reagents for the treatment of immunoinflammatory disorders
NZ555501A (en) 2004-11-24 2010-01-29 Medpointe Healthcare Inc Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
EP2298319A1 (en) 2005-04-04 2011-03-23 Sinexus, Inc. Device and methods for treating paranasal sinus conditions
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
CA2657581A1 (en) * 2006-07-11 2008-01-17 Roy C. Levitt Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
DE102006034883A1 (de) * 2006-07-25 2008-01-31 Hermal Kurt Herrmann Gmbh & Co. Ohg Pharmazeutische Zusammensetzung enthaltend Mometasonfuroat
EP2083798A1 (en) * 2006-10-19 2009-08-05 Cipla Limited Pharmaceutical compositions and nasal spray incorporating anhydrous mometasone furoate
CN103961193A (zh) 2007-12-18 2014-08-06 因特尔赛克特耳鼻喉公司 自扩展装置及用于其的方法
CA2732355A1 (en) 2008-08-01 2010-02-04 Intersect Ent, Inc. Methods and devices for crimping self-expanding devices
KR101099826B1 (ko) 2009-02-16 2011-12-27 서울대학교산학협력단 항알러지성 약물을 활성성분으로 함유하는 비강투여용 액상제제
CA2761769C (en) 2009-05-15 2018-06-05 Intersect Ent, Inc. Expandable devices and methods therefor
WO2011141929A2 (en) 2010-05-11 2011-11-17 Cadila Healthcare Limited Aqueous pharmaceutical compositions of fluticasone and olopatadine
FR2970180B1 (fr) * 2011-01-06 2013-08-02 Substipharm Dev Procede de preparation de suspensions aqueuses pharmaceutiques comprenant un medicament efficace dans le traitement des rhinites
WO2013042225A1 (ja) 2011-09-21 2013-03-28 三菱電機株式会社 炭化珪素半導体装置およびその製造方法
US10406332B2 (en) 2013-03-14 2019-09-10 Intersect Ent, Inc. Systems, devices, and method for treating a sinus condition
LT3043773T (lt) * 2013-09-13 2021-10-11 Glenmark Specialty S.A. Stabilios fiksuotos dozės farmacinė kompozicija, kurioje yra mometazono ir olopatadino, skirta naudoti į nosį
US9370483B2 (en) 2013-09-13 2016-06-21 Glenmark Specialty S.A. Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US9937189B2 (en) 2013-09-13 2018-04-10 Glenmark Specialty S.A. Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US10548907B2 (en) 2013-10-04 2020-02-04 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10016443B2 (en) 2013-10-04 2018-07-10 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
EP2922553A1 (en) 2013-10-04 2015-09-30 Glenmark Pharmaceuticals Limited Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10758550B2 (en) 2013-10-04 2020-09-01 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10653661B2 (en) 2013-10-04 2020-05-19 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US11679210B2 (en) 2014-10-03 2023-06-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
US20160120928A1 (en) * 2014-11-03 2016-05-05 Zent, Inc. Nasal spray
DK3331498T3 (da) * 2015-08-04 2020-06-15 Windstar Medical Gmbh Nasalsammensætning
CN106619504A (zh) * 2016-11-10 2017-05-10 北京万全德众医药生物技术有限公司 一种地氯雷他定口服滴剂及其制备方法
NZ766523A (en) * 2018-02-23 2025-07-25 Glenmark Specialty Sa Treatment of allergic rhinitis in pediatric subjects using a combination of mometasone and olopatadine
US12303635B2 (en) 2018-04-16 2025-05-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
WO2019245015A1 (ja) * 2018-06-22 2019-12-26 参天製薬株式会社 デスロラタジン又はその塩を含有する医薬組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA924164B (en) * 1991-06-10 1993-02-24 Schering Corp Non-chlorofluorocarbon aerosol formulations
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
EP0780127A1 (en) * 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
WO1997046243A1 (en) * 1996-06-04 1997-12-11 The Procter & Gamble Company A nasal spray containing an intranasal steroid and an antihistamine
US5939426A (en) * 1997-02-28 1999-08-17 Sepracor Inc. Methods for treating urinary incontinence using descarboethoxyloratadine
JP2001510485A (ja) * 1999-03-01 2001-07-31 シェーリング コーポレイション アトピー性皮膚炎、血管性浮腫および他の障害を抗ヒスタミン薬およびグルココルチコイドを用いて処置するための組成物および方法

Also Published As

Publication number Publication date
ES2284531T3 (es) 2007-11-16
WO2001026658A2 (en) 2001-04-19
JP2007106777A (ja) 2007-04-26
AU7859800A (en) 2001-04-23
AR025964A1 (es) 2002-12-26
JP2003511417A (ja) 2003-03-25
WO2001026658A3 (en) 2002-02-21
EP1227812A2 (en) 2002-08-07
DE60034476D1 (de) 2007-05-31
CA2383970A1 (en) 2001-04-19
EP1227812B1 (en) 2007-04-18
ATE359784T1 (de) 2007-05-15
JP2008056698A (ja) 2008-03-13

Similar Documents

Publication Publication Date Title
DE60034476T2 (de) Topische nasenbehandlung mit desloratadin und mometason furoat
DE69526425T2 (de) Verwendung von mometasone-furoat zur behandlung von luftweg- und lungenerkrankungen
US12310930B2 (en) Stabilization of epinephrine formulations
EP1283036B1 (de) Multidosis-Trockenpulverinhalator mit Pulverreservoir
DE69629591T2 (de) Formulierung zur intranasalen verabreichung
CA2822683C (en) Bepotastine compositions
EP2214658B1 (de) Osmolythaltige zubereitung zur anwendung bei trockenen schleimhäuten
EP1121112B1 (de) Lagerfähiges wirkstoffkonzentrat mit formoterol
DE60002885T2 (de) Wässrige formulierung zur nasalen verabreichung
EP3157522B1 (en) Muscarinic antagonists and combinations thereof for the treatment of airway disease in horses
EP0125634A1 (de) Verwendung einer sekretolytisch wirkenden Substanz zur Herstellung eines Antischnarchmittels und zur Bekämpfung des Schnarchphänomens
WO2015185195A1 (de) Silikonölhaltige nasal anzuwendende formulierungen
US11925608B2 (en) Stabilization of epinephrine formulations
EP2200603B1 (de) Osmolyte zur behandlung von allergisch bedingten atemwegserkrankungen
JP2011507895A (ja) オキシメタゾリンの増強された光安定化
DE60119976T2 (de) Thixotropes nasenspray
DE202009010937U1 (de) Monoterpene für die Behandlung von Atemwegserkrankungen, insbesondere von bronchopulmonalen Erkrankungen
CA3176555A1 (en) Stabilized menthol and other volatile compound compositions and methods
DE19847970A1 (de) Lagerfähige Wirkstoff-Formulierung
EP0529499A1 (de) Pharmazeutische Zusammensetzungen enthaltend Bradykinin-Antagonisten zur lokalen Anwendung an Nase und Auge
DE202006005924U1 (de) Zusammensetzung zur Behandlung von Rhinitis
DE10014007A1 (de) Neue Darreichungsformen für DSIP
DE3836579A1 (de) Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge

Legal Events

Date Code Title Description
8364 No opposition during term of opposition