DE60034117D1 - Verfahren zur herstelllung von gonadotropin-zusammensetzungen - Google Patents
Verfahren zur herstelllung von gonadotropin-zusammensetzungenInfo
- Publication number
- DE60034117D1 DE60034117D1 DE60034117T DE60034117T DE60034117D1 DE 60034117 D1 DE60034117 D1 DE 60034117D1 DE 60034117 T DE60034117 T DE 60034117T DE 60034117 T DE60034117 T DE 60034117T DE 60034117 D1 DE60034117 D1 DE 60034117D1
- Authority
- DE
- Germany
- Prior art keywords
- gonadotropins
- menotropins
- follitropin
- fsh
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 108010086677 Gonadotropins Proteins 0.000 abstract 4
- 102000006771 Gonadotropins Human genes 0.000 abstract 4
- 239000002622 gonadotropin Substances 0.000 abstract 4
- 229940094892 gonadotropins Drugs 0.000 abstract 4
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 abstract 2
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 abstract 2
- 108010057021 Menotropins Proteins 0.000 abstract 2
- 230000004071 biological effect Effects 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241000700159 Rattus Species 0.000 abstract 1
- 238000004166 bioassay Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12954099P | 1999-04-16 | 1999-04-16 | |
US129540P | 1999-04-16 | ||
PCT/EP2000/003357 WO2000063248A2 (en) | 1999-04-16 | 2000-04-14 | Highly purified gonadotropin compositions and process for preparing them |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60034117D1 true DE60034117D1 (de) | 2007-05-10 |
DE60034117T2 DE60034117T2 (de) | 2007-12-13 |
Family
ID=22440494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60034117T Expired - Lifetime DE60034117T2 (de) | 1999-04-16 | 2000-04-14 | Verfahren zur herstelllung von gonadotropin-zusammensetzungen |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1169349B1 (de) |
JP (1) | JP4574865B2 (de) |
AT (1) | ATE358139T1 (de) |
AU (1) | AU779005B2 (de) |
BR (1) | BRPI0010677B8 (de) |
CA (1) | CA2370225C (de) |
CY (1) | CY1107666T1 (de) |
DE (1) | DE60034117T2 (de) |
DK (1) | DK1169349T3 (de) |
ES (1) | ES2284494T3 (de) |
MX (1) | MXPA01010522A (de) |
PT (1) | PT1169349E (de) |
WO (1) | WO2000063248A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4763616B2 (ja) | 2003-12-22 | 2011-08-31 | アレス トレーディング ソシエテ アノニム | Fshを精製するための方法 |
MX2007005327A (es) * | 2004-11-09 | 2007-08-02 | Ares Trading Sa | Metodo para purificacion de la hormona foliculo estimulante (hfe). |
UA87709C2 (ru) * | 2004-11-09 | 2009-08-10 | Эйрэс Трейдинг С.А. | Способ очищения фолликулостимулирующего гормона |
SG155183A1 (en) | 2005-08-26 | 2009-09-30 | Ares Trading Sa | Process for the preparation of glycosylated interferon beta |
AU2006323925B2 (en) | 2005-12-09 | 2012-08-02 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
UA103598C2 (uk) | 2007-06-28 | 2013-11-11 | Биодженерикс Аг | Клон клітин, що продукують fsh |
WO2009098318A1 (en) | 2008-02-08 | 2009-08-13 | Biogenerix Ag | Liquid formulation of fsh |
CN101269215B (zh) * | 2008-05-15 | 2011-03-23 | 上海天伟生物制药有限公司 | 一种糖蛋白激素组合物 |
AU2010234028B2 (en) * | 2009-04-01 | 2013-11-14 | Theramex HQ UK Limited | Method for purifying recombinant FSH |
EP2325194A1 (de) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Verfahren zur Reinigung von Glykoproteinen |
CN103159846B (zh) * | 2013-04-09 | 2015-04-22 | 邹平县滨渤生物科技有限公司 | Hmg粗品的制备方法 |
JP6647220B2 (ja) * | 2014-05-23 | 2020-02-14 | インスティトゥート・マッソーネ・エセ・ア | Hmg−up(超高純度グレードのヒト閉経期ゴナドトロピン)を得るための方法及び夾雑物を含まない組成物 |
PL3261661T3 (pl) | 2015-02-26 | 2024-03-25 | Ferring B.V. | Menotropina do leczenia niepłodności |
CN108070640B (zh) * | 2018-01-12 | 2021-09-21 | 浙江省农业科学院 | 一种与卵泡刺激素剂量呈线性相关的基因的筛选方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1065127A (en) * | 1963-03-11 | 1967-04-12 | Serono Ist Farm | Pituitary gonadotropic hormone preparation and method for its production |
IT1287138B1 (it) * | 1996-11-07 | 1998-08-04 | Ibsa Inst Biochimique Sa | Procedimento per la separazione e purificazione di fsh e lh |
-
2000
- 2000-04-14 AT AT00926922T patent/ATE358139T1/de active
- 2000-04-14 MX MXPA01010522A patent/MXPA01010522A/es active IP Right Grant
- 2000-04-14 WO PCT/EP2000/003357 patent/WO2000063248A2/en active IP Right Grant
- 2000-04-14 BR BRPI0010677A patent/BRPI0010677B8/pt not_active IP Right Cessation
- 2000-04-14 CA CA2370225A patent/CA2370225C/en not_active Expired - Lifetime
- 2000-04-14 JP JP2000612334A patent/JP4574865B2/ja not_active Expired - Lifetime
- 2000-04-14 PT PT00926922T patent/PT1169349E/pt unknown
- 2000-04-14 DE DE60034117T patent/DE60034117T2/de not_active Expired - Lifetime
- 2000-04-14 AU AU45491/00A patent/AU779005B2/en not_active Expired
- 2000-04-14 ES ES00926922T patent/ES2284494T3/es not_active Expired - Lifetime
- 2000-04-14 EP EP00926922A patent/EP1169349B1/de not_active Expired - Lifetime
- 2000-04-14 DK DK00926922T patent/DK1169349T3/da active
-
2007
- 2007-06-11 CY CY20071100763T patent/CY1107666T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2370225A1 (en) | 2000-10-26 |
MXPA01010522A (es) | 2003-08-19 |
BR0010677B1 (pt) | 2013-04-30 |
CA2370225C (en) | 2010-06-29 |
WO2000063248A2 (en) | 2000-10-26 |
ES2284494T3 (es) | 2007-11-16 |
BR0010677A (pt) | 2002-02-05 |
DE60034117T2 (de) | 2007-12-13 |
AU4549100A (en) | 2000-11-02 |
JP4574865B2 (ja) | 2010-11-04 |
PT1169349E (pt) | 2007-06-18 |
CY1107666T1 (el) | 2013-04-18 |
EP1169349A2 (de) | 2002-01-09 |
BRPI0010677B8 (pt) | 2021-05-25 |
ATE358139T1 (de) | 2007-04-15 |
WO2000063248A3 (en) | 2001-02-01 |
JP2002542260A (ja) | 2002-12-10 |
DK1169349T3 (da) | 2007-07-30 |
AU779005B2 (en) | 2004-12-23 |
EP1169349B1 (de) | 2007-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |