IT1287138B1 - Procedimento per la separazione e purificazione di fsh e lh - Google Patents
Procedimento per la separazione e purificazione di fsh e lhInfo
- Publication number
- IT1287138B1 IT1287138B1 IT96MI002313A ITMI962313A IT1287138B1 IT 1287138 B1 IT1287138 B1 IT 1287138B1 IT 96MI002313 A IT96MI002313 A IT 96MI002313A IT MI962313 A ITMI962313 A IT MI962313A IT 1287138 B1 IT1287138 B1 IT 1287138B1
- Authority
- IT
- Italy
- Prior art keywords
- fsh
- separation
- optional
- ion
- purification
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 238000000926 separation method Methods 0.000 title abstract 2
- 239000011347 resin Substances 0.000 abstract 3
- 229920005989 resin Polymers 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000129 anionic group Chemical group 0.000 abstract 2
- 238000004255 ion exchange chromatography Methods 0.000 abstract 2
- BFSVOASYOCHEOV-UHFFFAOYSA-N 2-diethylaminoethanol Chemical compound CCN(CC)CCO BFSVOASYOCHEOV-UHFFFAOYSA-N 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 238000011082 depyrogenation Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Amplifiers (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- External Artificial Organs (AREA)
- Executing Machine-Instructions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI002313A IT1287138B1 (it) | 1996-11-07 | 1996-11-07 | Procedimento per la separazione e purificazione di fsh e lh |
| CA002242325A CA2242325C (en) | 1996-11-07 | 1997-11-03 | Fsh and lh separation and purification process |
| PT97950077T PT882064E (pt) | 1996-11-07 | 1997-11-03 | Processo de purificacao e separacao de fsh e lh |
| IL12522597A IL125225A (en) | 1996-11-07 | 1997-11-03 | Fsh and lh separation and purification process |
| ES97950077T ES2196380T3 (es) | 1996-11-07 | 1997-11-03 | Procedimiento de purificacion y de separacion de fsh y lh. |
| PCT/EP1997/006058 WO1998020039A1 (en) | 1996-11-07 | 1997-11-03 | Fsh and lh separation and purification process |
| EP97950077A EP0882064B1 (en) | 1996-11-07 | 1997-11-03 | Fsh and lh separation and purification process |
| DE69720693T DE69720693T2 (de) | 1996-11-07 | 1997-11-03 | Fsh und lh trennungs- und reinigungsverfahren |
| AU53162/98A AU719560B2 (en) | 1996-11-07 | 1997-11-03 | FSH and LH separation and purification process |
| AT97950077T ATE236931T1 (de) | 1996-11-07 | 1997-11-03 | Fsh und lh trennungs- und reinigungsverfahren |
| US09/111,090 US6162905A (en) | 1996-11-07 | 1998-07-06 | FSH and LH separation and purification process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI002313A IT1287138B1 (it) | 1996-11-07 | 1996-11-07 | Procedimento per la separazione e purificazione di fsh e lh |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI962313A0 ITMI962313A0 (it) | 1996-11-07 |
| ITMI962313A1 ITMI962313A1 (it) | 1998-05-07 |
| IT1287138B1 true IT1287138B1 (it) | 1998-08-04 |
Family
ID=11375168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT96MI002313A IT1287138B1 (it) | 1996-11-07 | 1996-11-07 | Procedimento per la separazione e purificazione di fsh e lh |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0882064B1 (it) |
| AT (1) | ATE236931T1 (it) |
| AU (1) | AU719560B2 (it) |
| CA (1) | CA2242325C (it) |
| DE (1) | DE69720693T2 (it) |
| ES (1) | ES2196380T3 (it) |
| IL (1) | IL125225A (it) |
| IT (1) | IT1287138B1 (it) |
| PT (1) | PT882064E (it) |
| WO (1) | WO1998020039A1 (it) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6414123B1 (en) * | 1997-10-21 | 2002-07-02 | Vitro Diagnostics, Inc. | Method for purifying FSH |
| PT1169349E (pt) * | 1999-04-16 | 2007-06-18 | Inst Massone S A | Composições de gonadotropina de altamente purificada e processo para a sua preparação |
| US7022822B1 (en) * | 1999-04-16 | 2006-04-04 | Instituto Massone S.A. | Highly purified gonadotropin compositions and process for preparing them |
| UA78676C2 (en) | 2000-02-22 | 2007-04-25 | Applied Research Systems | Purified lh |
| IL151308A0 (en) * | 2000-02-22 | 2003-04-10 | Applied Research Systems | PURIFICATION OF hCG AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT |
| ATE408624T1 (de) * | 2004-11-09 | 2008-10-15 | Ares Trading Sa | Verfahren zur reinigung von fsh |
| ES2664924T3 (es) | 2005-08-26 | 2018-04-24 | Ares Trading S.A. | Procedimiento para la preparación del interferón beta glicosilado |
| AU2006323925B2 (en) * | 2005-12-09 | 2012-08-02 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
| CN101397339B (zh) * | 2008-09-24 | 2012-07-25 | 上海天伟生物制药有限公司 | 糖蛋白中去除/灭活病毒的方法 |
| EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
| CN101792482B (zh) * | 2010-03-12 | 2012-11-21 | 丽珠医药集团股份有限公司 | 一种促性腺激素的纯化方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58157720A (ja) * | 1982-03-15 | 1983-09-19 | Nippon Chem Res Kk | 高純度の胎盤性性腺刺戟ホルモンの製造法 |
-
1996
- 1996-11-07 IT IT96MI002313A patent/IT1287138B1/it active IP Right Grant
-
1997
- 1997-11-03 DE DE69720693T patent/DE69720693T2/de not_active Expired - Lifetime
- 1997-11-03 CA CA002242325A patent/CA2242325C/en not_active Expired - Fee Related
- 1997-11-03 IL IL12522597A patent/IL125225A/en not_active IP Right Cessation
- 1997-11-03 AT AT97950077T patent/ATE236931T1/de active
- 1997-11-03 ES ES97950077T patent/ES2196380T3/es not_active Expired - Lifetime
- 1997-11-03 PT PT97950077T patent/PT882064E/pt unknown
- 1997-11-03 WO PCT/EP1997/006058 patent/WO1998020039A1/en active IP Right Grant
- 1997-11-03 EP EP97950077A patent/EP0882064B1/en not_active Expired - Lifetime
- 1997-11-03 AU AU53162/98A patent/AU719560B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2242325C (en) | 2008-04-29 |
| DE69720693D1 (de) | 2003-05-15 |
| ITMI962313A0 (it) | 1996-11-07 |
| EP0882064B1 (en) | 2003-04-09 |
| ES2196380T3 (es) | 2003-12-16 |
| AU5316298A (en) | 1998-05-29 |
| CA2242325A1 (en) | 1998-05-14 |
| IL125225A (en) | 2002-04-21 |
| EP0882064A1 (en) | 1998-12-09 |
| ATE236931T1 (de) | 2003-04-15 |
| PT882064E (pt) | 2003-08-29 |
| AU719560B2 (en) | 2000-05-11 |
| WO1998020039A1 (en) | 1998-05-14 |
| DE69720693T2 (de) | 2004-03-04 |
| IL125225A0 (en) | 1999-03-12 |
| ITMI962313A1 (it) | 1998-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |