DE60029084D1 - Neue depsipeptid-verbindung - Google Patents

Neue depsipeptid-verbindung

Info

Publication number
DE60029084D1
DE60029084D1 DE60029084T DE60029084T DE60029084D1 DE 60029084 D1 DE60029084 D1 DE 60029084D1 DE 60029084 T DE60029084 T DE 60029084T DE 60029084 T DE60029084 T DE 60029084T DE 60029084 D1 DE60029084 D1 DE 60029084D1
Authority
DE
Germany
Prior art keywords
depsipeptid
new
connection
activity
tgf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60029084T
Other languages
English (en)
Other versions
DE60029084T2 (de
Inventor
Koji Nagai
Nakako Arao
Kinya Sohda
Kazuma Kamigiri
Masamichi Mori
Nobuaki Shindo
Haruo Seto
Kazuo Shin-Ya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of DE60029084D1 publication Critical patent/DE60029084D1/de
Application granted granted Critical
Publication of DE60029084T2 publication Critical patent/DE60029084T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60029084T 1999-01-13 2000-01-12 Neue depsipeptid-verbindung Expired - Lifetime DE60029084T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP704099 1999-01-13
JP704099 1999-01-13
PCT/JP2000/000110 WO2000042062A1 (fr) 1999-01-13 2000-01-12 Nouveau compose a base de depsipeptide

Publications (2)

Publication Number Publication Date
DE60029084D1 true DE60029084D1 (de) 2006-08-10
DE60029084T2 DE60029084T2 (de) 2007-02-01

Family

ID=11654946

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60029084T Expired - Lifetime DE60029084T2 (de) 1999-01-13 2000-01-12 Neue depsipeptid-verbindung

Country Status (13)

Country Link
US (2) US6670326B1 (de)
EP (1) EP1142905B1 (de)
JP (1) JP3554707B2 (de)
KR (1) KR100611265B1 (de)
CN (1) CN1173990C (de)
AT (1) ATE331730T1 (de)
AU (1) AU2002700A (de)
CA (1) CA2356845C (de)
DE (1) DE60029084T2 (de)
DK (1) DK1142905T3 (de)
ES (1) ES2265906T3 (de)
PT (1) PT1142905E (de)
WO (1) WO2000042062A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2393682C (en) * 1999-12-08 2012-01-31 Xcyte Therapies, Inc. Depsipeptide and congeners thereof for use as immunosuppressants
CA2497281A1 (en) * 2002-08-30 2004-03-11 Yamanouchi Pharmaceutical Co., Ltd. Novel depsipeptide compound
EP1920779A4 (de) * 2005-08-12 2010-03-10 Astellas Pharma Inc Technik zur stabilisierung der yw753-reparatur
WO2007040522A1 (en) * 2005-09-30 2007-04-12 The Ohio State Research Foundation Antitumor agents
JP5178731B2 (ja) * 2006-11-22 2013-04-10 カルス セラピューティクス リミテッド デプシペプチドおよびその治療的使用
GB0623357D0 (en) * 2006-11-22 2007-01-03 Karus Therapeutics Ltd Chemical compounds
GB0623388D0 (en) * 2006-11-23 2007-01-03 Univ Southampton Chemical compounds
GB0715750D0 (en) * 2007-08-13 2007-09-19 Karus Therapeutics Ltd Chemical compounds
US20150352076A1 (en) 2013-01-25 2015-12-10 Toshiyuku SAKAI Molecularly targeted combination drug for tumor treatment and prevention

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61101501A (ja) 1984-10-24 1986-05-20 Yamanouchi Pharmaceut Co Ltd 制癌作用を有する多糖及びその製法
GB8817743D0 (en) 1988-07-26 1988-09-01 Fujisawa Pharmaceutical Co Fr901228 substance & preparation thereof
US5681813A (en) 1994-04-06 1997-10-28 Pharma Mar, S.A. Thiodepsipeptide isolated from a marine actinomycete

Also Published As

Publication number Publication date
ES2265906T3 (es) 2007-03-01
US6670326B1 (en) 2003-12-30
CN1173990C (zh) 2004-11-03
AU2002700A (en) 2000-08-01
KR20010101443A (ko) 2001-11-14
EP1142905A4 (de) 2004-05-19
DE60029084T2 (de) 2007-02-01
ATE331730T1 (de) 2006-07-15
US20040082054A1 (en) 2004-04-29
EP1142905B1 (de) 2006-06-28
KR100611265B1 (ko) 2006-08-10
CA2356845C (en) 2010-10-19
CN1335852A (zh) 2002-02-13
PT1142905E (pt) 2006-10-31
EP1142905A1 (de) 2001-10-10
WO2000042062A1 (fr) 2000-07-20
DK1142905T3 (da) 2006-09-18
US7098024B2 (en) 2006-08-29
CA2356845A1 (en) 2000-07-20
JP3554707B2 (ja) 2004-08-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition