DE60020269T2 - Verwendung von interleukin-6 antagonisten zur behandlung von oestrogen-abhängigen krebs - Google Patents

Verwendung von interleukin-6 antagonisten zur behandlung von oestrogen-abhängigen krebs Download PDF

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Publication number
DE60020269T2
DE60020269T2 DE60020269T DE60020269T DE60020269T2 DE 60020269 T2 DE60020269 T2 DE 60020269T2 DE 60020269 T DE60020269 T DE 60020269T DE 60020269 T DE60020269 T DE 60020269T DE 60020269 T2 DE60020269 T2 DE 60020269T2
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Germany
Prior art keywords
seq
aromatase
activity
preparation
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60020269T
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German (de)
English (en)
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DE60020269D1 (de
Inventor
John Michael REED
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
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Sigma Tau Industrie Farmaceutiche Riunite SpA
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Publication of DE60020269D1 publication Critical patent/DE60020269D1/de
Application granted granted Critical
Publication of DE60020269T2 publication Critical patent/DE60020269T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DE60020269T 2000-03-06 2000-03-06 Verwendung von interleukin-6 antagonisten zur behandlung von oestrogen-abhängigen krebs Expired - Fee Related DE60020269T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2000/000072 WO2001066131A1 (en) 2000-03-06 2000-03-06 Use of interleukin-6 antagonists for the treatment of diseases characterised by high levels of aromatase

Publications (2)

Publication Number Publication Date
DE60020269D1 DE60020269D1 (de) 2005-06-23
DE60020269T2 true DE60020269T2 (de) 2006-01-19

Family

ID=11133493

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60020269T Expired - Fee Related DE60020269T2 (de) 2000-03-06 2000-03-06 Verwendung von interleukin-6 antagonisten zur behandlung von oestrogen-abhängigen krebs

Country Status (17)

Country Link
US (1) US7160860B2 (https=)
EP (1) EP1261367B1 (https=)
JP (1) JP2003525906A (https=)
KR (1) KR100694005B1 (https=)
AT (1) ATE295735T1 (https=)
AU (1) AU2000233235A1 (https=)
CA (1) CA2400711A1 (https=)
CZ (1) CZ20022760A3 (https=)
DE (1) DE60020269T2 (https=)
DK (1) DK1261367T3 (https=)
ES (1) ES2241583T3 (https=)
HU (1) HUP0300117A3 (https=)
MX (1) MXPA02008697A (https=)
PL (1) PL356846A1 (https=)
PT (1) PT1261367E (https=)
SK (1) SK12412002A3 (https=)
WO (1) WO2001066131A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6793678B2 (en) 2002-06-27 2004-09-21 Depuy Acromed, Inc. Prosthetic intervertebral motion disc having dampening
US8105382B2 (en) 2006-12-07 2012-01-31 Interventional Spine, Inc. Intervertebral implant
US8900307B2 (en) 2007-06-26 2014-12-02 DePuy Synthes Products, LLC Highly lordosed fusion cage
EP2471493A1 (en) 2008-01-17 2012-07-04 Synthes GmbH An expandable intervertebral implant and associated method of manufacturing the same
CN102036623A (zh) 2008-04-05 2011-04-27 斯恩蒂斯有限公司 可膨胀的椎间植入体
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US9393129B2 (en) 2009-12-10 2016-07-19 DePuy Synthes Products, Inc. Bellows-like expandable interbody fusion cage
US8979860B2 (en) 2010-06-24 2015-03-17 DePuy Synthes Products. LLC Enhanced cage insertion device
US9282979B2 (en) 2010-06-24 2016-03-15 DePuy Synthes Products, Inc. Instruments and methods for non-parallel disc space preparation
AU2011271465B2 (en) 2010-06-29 2015-03-19 Synthes Gmbh Distractible intervertebral implant
US9402732B2 (en) 2010-10-11 2016-08-02 DePuy Synthes Products, Inc. Expandable interspinous process spacer implant
US8394129B2 (en) 2011-03-10 2013-03-12 Interventional Spine, Inc. Method and apparatus for minimally invasive insertion of intervertebral implants
US8518087B2 (en) 2011-03-10 2013-08-27 Interventional Spine, Inc. Method and apparatus for minimally invasive insertion of intervertebral implants
WO2014018098A1 (en) 2012-07-26 2014-01-30 DePuy Synthes Products, LLC Expandable implant
US9717601B2 (en) 2013-02-28 2017-08-01 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US9522070B2 (en) 2013-03-07 2016-12-20 Interventional Spine, Inc. Intervertebral implant
US11426290B2 (en) 2015-03-06 2022-08-30 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US9913727B2 (en) 2015-07-02 2018-03-13 Medos International Sarl Expandable implant
WO2018002715A2 (en) 2016-06-28 2018-01-04 Eit Emerging Implant Technologies Gmbh Expandable and angularly adjustable articulating intervertebral cages
EP3474783B1 (en) 2016-06-28 2023-05-03 Eit Emerging Implant Technologies GmbH Expandable, angularly adjustable intervertebral cages
US10537436B2 (en) 2016-11-01 2020-01-21 DePuy Synthes Products, Inc. Curved expandable cage
US10888433B2 (en) 2016-12-14 2021-01-12 DePuy Synthes Products, Inc. Intervertebral implant inserter and related methods
US10398563B2 (en) 2017-05-08 2019-09-03 Medos International Sarl Expandable cage
US11344424B2 (en) 2017-06-14 2022-05-31 Medos International Sarl Expandable intervertebral implant and related methods
US10940016B2 (en) 2017-07-05 2021-03-09 Medos International Sarl Expandable intervertebral fusion cage
US11446156B2 (en) 2018-10-25 2022-09-20 Medos International Sarl Expandable intervertebral implant, inserter instrument, and related methods
US11426286B2 (en) 2020-03-06 2022-08-30 Eit Emerging Implant Technologies Gmbh Expandable intervertebral implant
US11850160B2 (en) 2021-03-26 2023-12-26 Medos International Sarl Expandable lordotic intervertebral fusion cage
US11752009B2 (en) 2021-04-06 2023-09-12 Medos International Sarl Expandable intervertebral fusion cage
US12090064B2 (en) 2022-03-01 2024-09-17 Medos International Sarl Stabilization members for expandable intervertebral implants, and related systems and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276555B1 (it) * 1995-04-28 1997-11-03 Angeletti P Ist Richerche Bio Antagonisti di interluchina-6 umana del tutto incapaci di formare un legame con gp 130, e loro uso per la preparazione di composizioni
IT1285790B1 (it) * 1996-09-24 1998-06-24 Angeletti P Ist Richerche Bio Adenovirus difettivi ricombinanti che codificano per mutanti di interleuchina 6 umana (hil-6) con attivita' antagonista o
GB9621095D0 (en) * 1996-10-09 1996-11-27 Imperial College Novel system
US7205280B2 (en) * 1998-03-11 2007-04-17 Cognosci, Inc. Methods of suppressing microglial activation

Also Published As

Publication number Publication date
PT1261367E (pt) 2005-09-30
HUP0300117A3 (en) 2005-09-28
KR20020079984A (ko) 2002-10-21
MXPA02008697A (es) 2003-04-14
HUP0300117A2 (hu) 2003-04-28
WO2001066131A1 (en) 2001-09-13
CZ20022760A3 (cs) 2003-03-12
KR100694005B1 (ko) 2007-03-12
AU2000233235A1 (en) 2001-09-17
ATE295735T1 (de) 2005-06-15
DE60020269D1 (de) 2005-06-23
EP1261367B1 (en) 2005-05-18
DK1261367T3 (da) 2005-09-12
EP1261367A1 (en) 2002-12-04
US7160860B2 (en) 2007-01-09
US20050090443A1 (en) 2005-04-28
JP2003525906A (ja) 2003-09-02
ES2241583T3 (es) 2005-11-01
CA2400711A1 (en) 2001-09-13
SK12412002A3 (sk) 2002-12-03
PL356846A1 (en) 2004-07-12

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8339 Ceased/non-payment of the annual fee