DE60013857D1 - Gemisch und methode zur verbesserung der wundheilung - Google Patents
Gemisch und methode zur verbesserung der wundheilungInfo
- Publication number
- DE60013857D1 DE60013857D1 DE60013857T DE60013857T DE60013857D1 DE 60013857 D1 DE60013857 D1 DE 60013857D1 DE 60013857 T DE60013857 T DE 60013857T DE 60013857 T DE60013857 T DE 60013857T DE 60013857 D1 DE60013857 D1 DE 60013857D1
- Authority
- DE
- Germany
- Prior art keywords
- wounds
- dressing
- healing
- gel
- ascorbic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000029663 wound healing Effects 0.000 title 1
- 206010052428 Wound Diseases 0.000 abstract 6
- 208000027418 Wounds and injury Diseases 0.000 abstract 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 4
- 230000035876 healing Effects 0.000 abstract 3
- 102000012422 Collagen Type I Human genes 0.000 abstract 2
- 108010022452 Collagen Type I Proteins 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 2
- 235000010323 ascorbic acid Nutrition 0.000 abstract 2
- 239000011668 ascorbic acid Substances 0.000 abstract 2
- 229940096422 collagen type i Drugs 0.000 abstract 2
- 239000000499 gel Substances 0.000 abstract 2
- 206010006802 Burns second degree Diseases 0.000 abstract 1
- 206010006803 Burns third degree Diseases 0.000 abstract 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- -1 D-glucose polysaccharide Chemical class 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 208000004210 Pressure Ulcer Diseases 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 208000000558 Varicose Ulcer Diseases 0.000 abstract 1
- 238000005299 abrasion Methods 0.000 abstract 1
- 230000001464 adherent effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003399 chemotactic effect Effects 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000011236 particulate material Substances 0.000 abstract 1
- 239000006072 paste Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000037390 scarring Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
- 230000001228 trophic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/358,777 US6046160A (en) | 1999-07-22 | 1999-07-22 | Composition and method for enhancing wound healing |
| PCT/US2000/008813 WO2001007071A1 (en) | 1999-07-22 | 2000-03-31 | Composition and method for enhancing wound healing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60013857D1 true DE60013857D1 (de) | 2004-10-21 |
Family
ID=23411005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60013857T Expired - Lifetime DE60013857D1 (de) | 1999-07-22 | 2000-03-31 | Gemisch und methode zur verbesserung der wundheilung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6046160A (enExample) |
| EP (1) | EP1206271B1 (enExample) |
| JP (1) | JP2003505156A (enExample) |
| AT (1) | ATE275965T1 (enExample) |
| AU (1) | AU778792B2 (enExample) |
| BR (1) | BR0013038A (enExample) |
| CA (1) | CA2378760A1 (enExample) |
| DE (1) | DE60013857D1 (enExample) |
| WO (1) | WO2001007071A1 (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6528483B2 (en) | 1995-06-07 | 2003-03-04 | André Beaulieu | Method of producing concentrated non-buffered solutions of fibronectin |
| US7112320B1 (en) | 1995-06-07 | 2006-09-26 | Andre Beaulieu | Solid wound healing formulations containing fibronectin |
| ATE220564T1 (de) * | 1997-08-14 | 2002-08-15 | Sulzer Innotec Ag | Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren |
| US6046160A (en) * | 1999-07-22 | 2000-04-04 | Deroyal Industries, Inc. | Composition and method for enhancing wound healing |
| US6992062B2 (en) * | 2000-05-31 | 2006-01-31 | Encelle, Inc. | Method of stimulation hair growth |
| US6432425B1 (en) | 2000-09-08 | 2002-08-13 | Al Siamon | Method for treatment with an antibacterial and antiseptic mixture |
| US6695824B2 (en) | 2001-04-16 | 2004-02-24 | The United States Of America As Represented By The Secretary Of The Army | Wound dressing system |
| US20030068297A1 (en) * | 2001-08-18 | 2003-04-10 | Deepak Jain | Composition and methods for skin rejuvenation and repair |
| RU2232551C2 (ru) * | 2002-01-08 | 2004-07-20 | Ковалев Алексей Вячеславович | Способ аутотрансплантации клеток кожи |
| EP1342474A1 (en) * | 2002-03-08 | 2003-09-10 | Universiteit Leiden | The use of proline, poly-proline peptides and proline-rich proteins to quench reactive oxygen species |
| US20030206893A1 (en) * | 2002-05-06 | 2003-11-06 | Sohail Malik | Cell proliferating agents |
| US20040001878A1 (en) * | 2002-06-26 | 2004-01-01 | Deroyal Industries, Inc. | Infused wound care dressings |
| US7290197B2 (en) * | 2003-06-03 | 2007-10-30 | Quantum Corporation | Correcting data using redundancy blocks |
| US8673366B2 (en) * | 2004-06-14 | 2014-03-18 | Kareem I. Batarseh | Chemotherapeutic and prophylactic pharmaceutical compositions |
| US7754194B2 (en) * | 2005-04-06 | 2010-07-13 | L'oréal | Hair relaxer compositions utilizing bioactive glass |
| WO2006135848A2 (en) * | 2005-06-10 | 2006-12-21 | Pamela Howard | Wound management system |
| US20060293228A1 (en) * | 2005-06-24 | 2006-12-28 | Bhatnagar Rajendra S | Therapeutic compositions and methods using transforming growth factor-beta mimics |
| US20070003541A1 (en) * | 2005-07-01 | 2007-01-04 | Rodolfo Faudoa | Methods and compositions for therapeutics |
| US20070004036A1 (en) * | 2005-07-01 | 2007-01-04 | Rodolfo Faudoa | Methods and compositions for keratinocyte culture |
| US20070128685A1 (en) * | 2005-07-01 | 2007-06-07 | Rodolfo Faudoa | Methods and compositions for cell culture |
| CA2623940C (en) * | 2005-09-27 | 2017-01-10 | Tissuetech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
| US20070077220A1 (en) * | 2005-09-30 | 2007-04-05 | Ramirez Jose E | Stable ascorbic acid compositions |
| US20070269534A1 (en) * | 2006-02-02 | 2007-11-22 | Ramirez Jose E | Methods of treating skin to enhance therapeutic treatment thereof |
| US20070178058A1 (en) * | 2006-02-02 | 2007-08-02 | Ramirez Jose E | Methods of using stable ascorbic acid compositions |
| US7834153B2 (en) * | 2006-06-05 | 2010-11-16 | University Of South Florida | Combination of insulin and ascorbate to enhance wound healing |
| KR101670099B1 (ko) | 2008-10-06 | 2016-10-27 | 가부시끼가이샤 쓰리디 매트릭스 | 조직 폐색제 |
| US8034363B2 (en) * | 2008-12-11 | 2011-10-11 | Advanced Technologies And Regenerative Medicine, Llc. | Sustained release systems of ascorbic acid phosphate |
| FR2945043B1 (fr) * | 2009-04-30 | 2019-07-26 | Roquette Freres | Procede de purification de polymeres de glucose destines aux solutions de dialyse peritoneale |
| US20150093449A1 (en) * | 2009-06-24 | 2015-04-02 | Donald H. Brancato | Method of Using Silicon Substituted Phosphates to Improve Healing of Bone and Soft Tissue |
| US8591459B2 (en) | 2009-12-21 | 2013-11-26 | Ethicon Endo-Surgery, Inc. | Use of biomarkers and therapeutic agents with surgical devices |
| WO2011139228A1 (en) | 2010-05-07 | 2011-11-10 | Empire Technology Development Llc | Nano scale collagen particles and membranes |
| CN102008740B (zh) * | 2010-12-01 | 2014-11-12 | 吴涛 | 一种可吸收生长因子复合敷料 |
| WO2012149486A1 (en) | 2011-04-28 | 2012-11-01 | Tissuetech, Inc. | Methods of modulating bone remodeling |
| US20130085461A1 (en) * | 2011-10-04 | 2013-04-04 | Dermal Therapy (Barbados) Inc. | Method for Pre-Debriding Treatment of Non-Viable Skin Tissue and Compositions and System Thereof |
| US20140330192A1 (en) * | 2012-02-13 | 2014-11-06 | The Ex Plant Company | Dressing for application to a wound or burn |
| EP2869903B1 (en) | 2012-07-06 | 2018-11-28 | 3-D Matrix Ltd. | Fill-finish process for peptide solutions |
| CA2890177A1 (en) * | 2012-11-08 | 2014-05-15 | Summa Health System | Vitamin c, vitamin k, a polyphenol, and combinations thereof for wound healing |
| US9393278B2 (en) | 2013-06-26 | 2016-07-19 | Han Sheng Biotech Co., Ltd. | Method for wound healing |
| EP3116524B1 (en) | 2014-03-10 | 2018-11-28 | 3-D Matrix Ltd. | Autoassembling peptides for the treatment of pulmonary bulla |
| BR112016019510A2 (pt) | 2014-03-10 | 2017-10-24 | 3 D Matrix Ltd | esterilização e filtração de composições de peptídeos |
| CN117138022A (zh) | 2014-03-10 | 2023-12-01 | 三维矩阵有限责任公司 | 自组装肽组合物 |
| TW201603818A (zh) | 2014-06-03 | 2016-02-01 | 組織科技股份有限公司 | 組成物及方法 |
| US20160243288A1 (en) | 2015-02-23 | 2016-08-25 | Tissuetech, Inc. | Apparatuses and methods for treating ophthalmic diseases and disorders |
| US10342831B2 (en) | 2015-05-20 | 2019-07-09 | Tissuetech, Inc. | Composition and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells |
| US10814038B2 (en) | 2016-01-06 | 2020-10-27 | 3-D Matrix, Ltd. | Combination compositions |
| TW201733600A (zh) | 2016-01-29 | 2017-10-01 | 帝聖工業公司 | 胎兒扶持組織物及使用方法 |
| CN110997020A (zh) * | 2017-02-08 | 2020-04-10 | Hkl医疗有限责任公司 | 位点内施用和剂量方法以及其中使用的药物 |
| CN111712230B (zh) | 2017-12-15 | 2024-04-26 | 立美基股份有限公司 | 表面活性剂肽纳米结构及在药物递送中的用途 |
| WO2020139689A1 (en) | 2018-12-26 | 2020-07-02 | Kim Katherine Echo | Compositions and methods for treating burns, wounds, and skin disorders |
| MX2022000877A (es) | 2019-07-24 | 2022-02-11 | Histocell Sl | Nueva composicion antioxidante para cicatrizacion de heridas. |
| US11000540B1 (en) | 2019-11-22 | 2021-05-11 | Al Siamon | Treatment for reducing adverse events including chemotherapy discomfort and other conditions |
| US11253595B2 (en) | 2019-11-22 | 2022-02-22 | Al Siamon | Treatment for reducing adverse events including chemotherapy discomfort and other conditions |
| GB201919385D0 (en) | 2019-12-27 | 2020-02-05 | Phoenix Eagle Company Pty Ltd | Compositions and methods of manufacture |
| CN114591419B (zh) * | 2022-03-07 | 2022-09-23 | 山东大学 | 一种热水解蛋白及其制备方法和应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1165243A (en) * | 1980-02-19 | 1984-04-10 | Anthony N. Silvetti | Method and composition for treatment of wounds |
| US4570629A (en) * | 1982-03-17 | 1986-02-18 | University Of Illinois Foundation | Hydrophilic biopolymeric copolyelectrolytes, and biodegradable wound dressing comprising same |
| AU546872B2 (en) * | 1982-06-16 | 1985-09-26 | Unilever Plc | Skin treatment compositions containing a fatty acid or ester |
| US4837024A (en) * | 1984-02-24 | 1989-06-06 | The Regents Of The University Of California | Compositions, articles and mehtod for improving wound healing |
| US4837285A (en) * | 1984-03-27 | 1989-06-06 | Medimatrix | Collagen matrix beads for soft tissue repair |
| JPS62161729A (ja) * | 1985-10-22 | 1987-07-17 | アンソニ− エヌ シルベツテイ シニア | 単糖を含有する創傷治療剤 |
| ATE78166T1 (de) * | 1985-10-22 | 1992-08-15 | Silvetti Anthony N | Monosaccharide enthaltende zusammensetzung zum heilen von wunden. |
| CA1294546C (en) * | 1986-04-23 | 1992-01-21 | John S. Sundsmo | Wound healing composition containing collagen |
| US5196196A (en) * | 1986-06-03 | 1993-03-23 | Incyte Pharmaceuticals, Inc. | Use of protease nexin-I in wound dressings |
| US5133965A (en) * | 1988-06-08 | 1992-07-28 | Fountain Pharmaceuticals, Inc. | Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution |
| GB9027106D0 (en) * | 1990-12-13 | 1991-02-06 | Cerester Holding B V | Starch composition |
| US5177065A (en) * | 1990-12-26 | 1993-01-05 | Silvetti Sr Anthony N | Monosaccharide containing wound healing preparation |
| US5633285A (en) * | 1991-03-01 | 1997-05-27 | Warner-Lambert Company | Cytoprotective wound healing compositions and methods for preparing and using same |
| US5874479A (en) * | 1991-03-01 | 1999-02-23 | Warner-Lambert Company | Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same |
| US5658956A (en) * | 1991-03-01 | 1997-08-19 | Warner-Lambert Company | Bioadhesive-wound healing compositions and methods for preparing and using same |
| US5658957A (en) * | 1991-03-01 | 1997-08-19 | Warner Lambert Company | Immunostimulating wound healing compositions and method for preparing and using same |
| JP3506701B2 (ja) * | 1991-11-26 | 2004-03-15 | ワーナー−ランバート・カンパニー | 創傷治癒組成物,その調製方法と使用 |
| DE69324011T2 (de) * | 1992-06-08 | 1999-10-07 | Pitmy International N.V., Bonaire | Distickstoffmonoxide enthaldendes dermatologisches präparat |
| GB2276819B (en) * | 1993-03-23 | 1996-12-11 | Johnson & Johnson Medical | Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol |
| GB2291348B (en) * | 1994-07-18 | 1999-01-20 | Johnson & Johnson Medical | Sterile gel composition for wound treatment comprising alginate and polyhydric alcohol |
| GB9415739D0 (en) * | 1994-07-30 | 1994-09-21 | Scimat Ltd | Gel wound dressing |
| US5578576A (en) * | 1994-09-02 | 1996-11-26 | Dalhousie University | Method and composition for treating intestinal wounds or ulcers |
| US5676967A (en) * | 1995-04-18 | 1997-10-14 | Brennen Medical, Inc. | Mesh matrix wound dressing |
| AU7519396A (en) * | 1995-10-26 | 1997-05-15 | Lange Medical Products, Inc. | Method of treating wounds with a gel composition |
| US5800372A (en) * | 1996-01-09 | 1998-09-01 | Aerojet-General Corporation | Field dressing for control of exsanguination |
| US5834008A (en) * | 1996-09-19 | 1998-11-10 | U.S. Biomaterials Corp. | Composition and method for acceleration of wound and burn healing |
| CA2308146A1 (en) * | 1997-07-28 | 1999-02-04 | Thomas B. Neff | Collagen type i and type iii adhesive compositions |
| US6046160A (en) * | 1999-07-22 | 2000-04-04 | Deroyal Industries, Inc. | Composition and method for enhancing wound healing |
-
1999
- 1999-07-22 US US09/358,777 patent/US6046160A/en not_active Expired - Lifetime
- 1999-12-10 US US09/459,753 patent/US6187743B1/en not_active Expired - Lifetime
-
2000
- 2000-03-31 BR BR0013038-9A patent/BR0013038A/pt not_active IP Right Cessation
- 2000-03-31 EP EP00921622A patent/EP1206271B1/en not_active Expired - Lifetime
- 2000-03-31 AT AT00921622T patent/ATE275965T1/de not_active IP Right Cessation
- 2000-03-31 AU AU41915/00A patent/AU778792B2/en not_active Ceased
- 2000-03-31 JP JP2001511954A patent/JP2003505156A/ja active Pending
- 2000-03-31 DE DE60013857T patent/DE60013857D1/de not_active Expired - Lifetime
- 2000-03-31 CA CA002378760A patent/CA2378760A1/en not_active Abandoned
- 2000-03-31 WO PCT/US2000/008813 patent/WO2001007071A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1206271A4 (en) | 2003-03-26 |
| AU778792B2 (en) | 2004-12-23 |
| ATE275965T1 (de) | 2004-10-15 |
| BR0013038A (pt) | 2002-04-30 |
| AU4191500A (en) | 2001-02-13 |
| US6046160A (en) | 2000-04-04 |
| JP2003505156A (ja) | 2003-02-12 |
| WO2001007071A1 (en) | 2001-02-01 |
| US6187743B1 (en) | 2001-02-13 |
| CA2378760A1 (en) | 2001-02-01 |
| EP1206271B1 (en) | 2004-09-15 |
| EP1206271A1 (en) | 2002-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |