DE60004348D1 - Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate - Google Patents

Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate

Info

Publication number
DE60004348D1
DE60004348D1 DE60004348T DE60004348T DE60004348D1 DE 60004348 D1 DE60004348 D1 DE 60004348D1 DE 60004348 T DE60004348 T DE 60004348T DE 60004348 T DE60004348 T DE 60004348T DE 60004348 D1 DE60004348 D1 DE 60004348D1
Authority
DE
Germany
Prior art keywords
anthracyclin
morpholin
combined preparations
platin derivatives
platin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60004348T
Other languages
English (en)
Other versions
DE60004348T2 (de
Inventor
Cristina Geroni
Marina Ripamonti
Michele Caruso
Antonino Suarato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nerviano Medical Sciences SRL
Original Assignee
Pharmacia Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia SpA filed Critical Pharmacia Italia SpA
Publication of DE60004348D1 publication Critical patent/DE60004348D1/de
Application granted granted Critical
Publication of DE60004348T2 publication Critical patent/DE60004348T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE60004348T 1999-04-29 2000-04-04 Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate Expired - Lifetime DE60004348T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9909925.1A GB9909925D0 (en) 1999-04-29 1999-04-29 Combined preparations comprising anthracycline derivatives
GB9909925 1999-04-29
PCT/EP2000/002923 WO2000066093A2 (en) 1999-04-29 2000-04-04 Combined preparations comprising morpholine anthracyclines and anticancer agent

Publications (2)

Publication Number Publication Date
DE60004348D1 true DE60004348D1 (de) 2003-09-11
DE60004348T2 DE60004348T2 (de) 2004-02-26

Family

ID=10852508

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60039260T Expired - Lifetime DE60039260D1 (de) 1999-04-29 2000-04-04 Kombinationspräparat enthaltend ein Morpholinyl Anthracyclinderivat und einen Topoisomerase II Inhibitor
DE60004348T Expired - Lifetime DE60004348T2 (de) 1999-04-29 2000-04-04 Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60039260T Expired - Lifetime DE60039260D1 (de) 1999-04-29 2000-04-04 Kombinationspräparat enthaltend ein Morpholinyl Anthracyclinderivat und einen Topoisomerase II Inhibitor

Country Status (16)

Country Link
US (2) US6537990B1 (de)
EP (3) EP1323423B1 (de)
JP (1) JP2002543112A (de)
CN (5) CN1507869A (de)
AR (1) AR023616A1 (de)
AT (2) ATE246507T1 (de)
AU (1) AU4397700A (de)
DE (2) DE60039260D1 (de)
DK (1) DK1173187T3 (de)
ES (2) ES2204572T3 (de)
GB (1) GB9909925D0 (de)
HK (1) HK1045462B (de)
MY (1) MY136610A (de)
PT (1) PT1173187E (de)
TW (1) TWI222863B (de)
WO (1) WO2000066093A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9916882D0 (en) * 1999-07-19 1999-09-22 Pharmacia & Upjohn Spa Antitumor synergistic composition
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
US20030133939A1 (en) * 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
WO2002072085A1 (en) * 2001-03-14 2002-09-19 Bristol-Myers Squibb Company Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
US20080075762A1 (en) * 2001-10-03 2008-03-27 Paul Tardi Compositions for delivery of drug combinations
CA2383259A1 (en) 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
JP4502641B2 (ja) * 2002-01-24 2010-07-14 ティルタン ファーマ リミテッド 抗癌組み合わせおよびその使用方法
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
ATE366579T1 (de) * 2003-02-26 2007-08-15 Nerviano Medical Sciences Srl Verfahren zur behandlung von leberkrebs durch intrahepatische verabreichung von nemorubicin
AU2004222527A1 (en) * 2003-03-18 2004-09-30 Pharmacia Italia Spa Combined therapy comprising nemorubicin and a cyclooxygenase-2-inhibitor
CN100500212C (zh) * 2005-04-06 2009-06-17 山东蓝金生物工程有限公司 一种抗实体肿瘤药物组合物
DK1912675T3 (en) 2005-07-25 2014-03-24 Emergent Product Dev Seattle B-cell reduction using specific and cd37-cd20-specific binding molecules
US7776832B2 (en) 2006-04-21 2010-08-17 Gem Pharmaceuticals, Llc Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines
JP2009539413A (ja) 2006-06-12 2009-11-19 トゥルビオン・ファーマシューティカルズ・インコーポレーテッド エフェクター機能を有する単鎖多価結合タンパク質
US20090004134A1 (en) * 2006-09-08 2009-01-01 Obeid Michel Sarkis Kit for treating a health condition by inducing translocation of an erp57 protein to a cellular membrane
WO2008092796A1 (en) * 2007-01-29 2008-08-07 Nerviano Medical Sciences S.R.L. Antitumor combination comprising a morpholinyl anthracycline and an antibody
ES2552718T3 (es) 2007-05-11 2015-12-01 Nerviano Medical Sciences S.R.L. Composición farmacéutica de una antraciclina
EP2257310A2 (de) * 2008-02-26 2010-12-08 Nerviano Medical Sciences S.r.l. Antitumorale kombination aus einem morpholinyl-anthracyclin-derivat und demethylierungsmitteln
ES2368700T3 (es) * 2008-04-11 2011-11-21 Emergent Product Development Seattle, Llc Agente inmunoterapéutico para cd37 y combinación con un agente quimioterapéutico bifuncional del mismo.
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
EP4349414A2 (de) 2014-12-23 2024-04-10 Dyve Biosciences, Inc. Verfahren und formulierungen zur transdermalen verabreichung
EP3352760A4 (de) 2015-09-21 2019-03-06 Aptevo Research and Development LLC Cd3-bindende polypeptide
US20190083386A1 (en) 2017-09-15 2019-03-21 Ampersand Biopharmaceuticals, Inc. Methods and formulations for transdermal administration of buffering agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
US5902809A (en) * 1997-07-03 1999-05-11 Paracure, Inc. Arglabin compounds and therapeutic uses thereof
GB9806324D0 (en) * 1998-03-24 1998-05-20 Pharmacia & Upjohn Spa Antitumour synergetic composition
GB9820012D0 (en) * 1998-09-14 1998-11-04 Pharmacia & Upjohn Spa Use of an anthracycline derivative for the treatment of a liver tumor

Also Published As

Publication number Publication date
TWI222863B (en) 2004-11-01
HK1045462B (zh) 2006-04-28
EP1323423B1 (de) 2008-06-18
ATE398457T1 (de) 2008-07-15
GB9909925D0 (en) 1999-06-30
CN1535688A (zh) 2004-10-13
CN1349406A (zh) 2002-05-15
AU4397700A (en) 2000-11-17
AR023616A1 (es) 2002-09-04
EP1173187B1 (de) 2003-08-06
HK1045462A1 (en) 2002-11-29
EP1173187A2 (de) 2002-01-23
CN1853642A (zh) 2006-11-01
EP1977753A1 (de) 2008-10-08
PT1173187E (pt) 2003-10-31
MY136610A (en) 2008-10-31
US6537990B1 (en) 2003-03-25
DK1173187T3 (da) 2003-10-20
CN1507869A (zh) 2004-06-30
CN1853645A (zh) 2006-11-01
CN1222294C (zh) 2005-10-12
WO2000066093A3 (en) 2001-01-25
JP2002543112A (ja) 2002-12-17
US6586428B2 (en) 2003-07-01
ES2307867T3 (es) 2008-12-01
WO2000066093A2 (en) 2000-11-09
DE60039260D1 (de) 2008-07-31
EP1323423A1 (de) 2003-07-02
US20030087839A1 (en) 2003-05-08
DE60004348T2 (de) 2004-02-26
ES2204572T3 (es) 2004-05-01
ATE246507T1 (de) 2003-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NERVIANO MEDICAL SCIENCES S.R.L., NERVIANO, MI, IT