ATE246507T1 - Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate - Google Patents

Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate

Info

Publication number
ATE246507T1
ATE246507T1 AT00925158T AT00925158T ATE246507T1 AT E246507 T1 ATE246507 T1 AT E246507T1 AT 00925158 T AT00925158 T AT 00925158T AT 00925158 T AT00925158 T AT 00925158T AT E246507 T1 ATE246507 T1 AT E246507T1
Authority
AT
Austria
Prior art keywords
anthracycline
preparations containing
platinum derivatives
combined preparations
containing morpholine
Prior art date
Application number
AT00925158T
Other languages
English (en)
Inventor
Maria Cristina Geroni
Marina Ripamonti
Michele Caruso
Antonino Suarato
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Application granted granted Critical
Publication of ATE246507T1 publication Critical patent/ATE246507T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT00925158T 1999-04-29 2000-04-04 Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate ATE246507T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9909925.1A GB9909925D0 (en) 1999-04-29 1999-04-29 Combined preparations comprising anthracycline derivatives
PCT/EP2000/002923 WO2000066093A2 (en) 1999-04-29 2000-04-04 Combined preparations comprising morpholine anthracyclines and anticancer agent

Publications (1)

Publication Number Publication Date
ATE246507T1 true ATE246507T1 (de) 2003-08-15

Family

ID=10852508

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03075776T ATE398457T1 (de) 1999-04-29 2000-04-04 Kombinationspräparat enthaltend ein morpholinyl anthracyclinderivat und einen topoisomerase ii inhibitor
AT00925158T ATE246507T1 (de) 1999-04-29 2000-04-04 Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03075776T ATE398457T1 (de) 1999-04-29 2000-04-04 Kombinationspräparat enthaltend ein morpholinyl anthracyclinderivat und einen topoisomerase ii inhibitor

Country Status (16)

Country Link
US (2) US6537990B1 (de)
EP (3) EP1173187B1 (de)
JP (1) JP2002543112A (de)
CN (5) CN1507869A (de)
AR (1) AR023616A1 (de)
AT (2) ATE398457T1 (de)
AU (1) AU4397700A (de)
DE (2) DE60004348T2 (de)
DK (1) DK1173187T3 (de)
ES (2) ES2307867T3 (de)
GB (1) GB9909925D0 (de)
HK (1) HK1045462B (de)
MY (1) MY136610A (de)
PT (1) PT1173187E (de)
TW (1) TWI222863B (de)
WO (1) WO2000066093A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9916882D0 (en) * 1999-07-19 1999-09-22 Pharmacia & Upjohn Spa Antitumor synergistic composition
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
US20030133939A1 (en) * 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
WO2002072085A1 (en) * 2001-03-14 2002-09-19 Bristol-Myers Squibb Company Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
CA2383259A1 (en) 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US20080075762A1 (en) * 2001-10-03 2008-03-27 Paul Tardi Compositions for delivery of drug combinations
JP4502641B2 (ja) * 2002-01-24 2010-07-14 ティルタン ファーマ リミテッド 抗癌組み合わせおよびその使用方法
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
WO2004075904A1 (en) * 2003-02-26 2004-09-10 Pharmacia Italia Spa Method for treating liver cancer by intrahepatic administration of nemorubicin
CA2519310A1 (en) * 2003-03-18 2004-09-30 Maria Adele Pacciarini Combined therapy comprising nemorubicin and a cyclooxygenase-2-inhibitor
CN100500212C (zh) * 2005-04-06 2009-06-17 山东蓝金生物工程有限公司 一种抗实体肿瘤药物组合物
SI1912675T1 (sl) * 2005-07-25 2014-07-31 Emergent Product Development Seattle, Llc zmanjšanje števila celic B z uporabo molekul, ki se specifično vežejo na CD37 in CD20
US7776832B2 (en) * 2006-04-21 2010-08-17 Gem Pharmaceuticals, Llc Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines
MX363905B (es) 2006-06-12 2019-04-08 Aptevo Res & Development Llc Proteinas de union multivalentes monocatenarias con funcion efectora.
US20090004134A1 (en) * 2006-09-08 2009-01-01 Obeid Michel Sarkis Kit for treating a health condition by inducing translocation of an erp57 protein to a cellular membrane
WO2008092796A1 (en) * 2007-01-29 2008-08-07 Nerviano Medical Sciences S.R.L. Antitumor combination comprising a morpholinyl anthracycline and an antibody
EP2152236B1 (de) 2007-05-11 2015-09-02 Nerviano Medical Sciences S.r.l. Pharmazeutische zusammensetzung eines anthrazyklins
WO2009106549A2 (en) * 2008-02-26 2009-09-03 Nerviano Medical Sciences S.R.L. Antitumor combination comprising a morpholinyl anthracycline derivative and demethylating agents
EP2132228B1 (de) 2008-04-11 2011-06-22 Emergent Product Development Seattle, LLC Cd37-immuntherapeutikum und kombination mit bifunktionellem chemotherapeutikum davon
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
CA2972065A1 (en) 2014-12-23 2016-06-30 Intellectual Property Associates, Llc Methods and formulations for transdermal administration
WO2017053469A2 (en) 2015-09-21 2017-03-30 Aptevo Research And Development Llc Cd3 binding polypeptides
US20190083386A1 (en) 2017-09-15 2019-03-21 Ampersand Biopharmaceuticals, Inc. Methods and formulations for transdermal administration of buffering agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
US5902809A (en) * 1997-07-03 1999-05-11 Paracure, Inc. Arglabin compounds and therapeutic uses thereof
GB9806324D0 (en) * 1998-03-24 1998-05-20 Pharmacia & Upjohn Spa Antitumour synergetic composition
GB9820012D0 (en) * 1998-09-14 1998-11-04 Pharmacia & Upjohn Spa Use of an anthracycline derivative for the treatment of a liver tumor

Also Published As

Publication number Publication date
DE60039260D1 (de) 2008-07-31
CN1222294C (zh) 2005-10-12
AU4397700A (en) 2000-11-17
WO2000066093A3 (en) 2001-01-25
DK1173187T3 (da) 2003-10-20
US20030087839A1 (en) 2003-05-08
GB9909925D0 (en) 1999-06-30
DE60004348D1 (de) 2003-09-11
JP2002543112A (ja) 2002-12-17
DE60004348T2 (de) 2004-02-26
EP1173187B1 (de) 2003-08-06
MY136610A (en) 2008-10-31
ES2204572T3 (es) 2004-05-01
CN1853645A (zh) 2006-11-01
WO2000066093A2 (en) 2000-11-09
CN1349406A (zh) 2002-05-15
TWI222863B (en) 2004-11-01
EP1323423A1 (de) 2003-07-02
PT1173187E (pt) 2003-10-31
AR023616A1 (es) 2002-09-04
CN1535688A (zh) 2004-10-13
EP1323423B1 (de) 2008-06-18
US6537990B1 (en) 2003-03-25
CN1853642A (zh) 2006-11-01
US6586428B2 (en) 2003-07-01
ES2307867T3 (es) 2008-12-01
HK1045462B (zh) 2006-04-28
EP1977753A1 (de) 2008-10-08
ATE398457T1 (de) 2008-07-15
EP1173187A2 (de) 2002-01-23
HK1045462A1 (en) 2002-11-29
CN1507869A (zh) 2004-06-30

Similar Documents

Publication Publication Date Title
ATE246507T1 (de) Kombinierte vorbereitungen, die morpholin anthracyclin und platin derivate
ZA200102588B (en) Aryl-substituted propanolamine derivatives, methods for their production, medicaments containing said compounds and their use.
IL152448A0 (en) 3-nitrogen-6, 7-dioxygen steroid derivatives and pharmaceutical compositions containing the same
MXPA03003246A (es) Derivados de indolina y su uso como ligandos del receptor 5-ht2.
ZA200007638B (en) Pyrazoline derivatives, their preparation and application as medicaments.
HUP0204474A3 (en) 1h-imidazopyridine derivatives, pharmaceutical compositions containing them and their use
NO20011216L (no) Azetidinderivater, deres fremstilling og medikamenter inneholdende forbindelsene
HUP0105414A3 (en) Pyrrolo-isoquinoline, azepino- and diazepino-indole derivatives, their use and pharmaceutical compisitions containing them
MXPA02001508A (es) Derivados de arilmetil-carbonilamino-tiazol y sus usos como agentes antitumorales.
NO20021379D0 (no) Benzodiazepin-derivater, fremstilling og anvendelse derav
MXPA03004644A (es) Derivados de fenilacetamdia-pirazol y su uso como agentes antitumorales.
HUP0401648A3 (en) 6-hydroxy isoflavon compounds, their derivatives and medicaments involving the same
HUP0105003A3 (en) 2-oxy-4h-3,1-benzoxazin-4-one derivatives, their use and pharmaceutical compositions containing them
PL344346A1 (en) Platinum complex, its preparation and therapeutic application
ZA993345B (en) Nefazodone dosage form.
HUP0400551A2 (en) Piperazine derivatives, their preparation and pharmaceutical compositions containing them
PL366378A1 (en) Benzoxazinone derivatives, their preparation and use
ATE266637T1 (de) 3,3-biarylpiperidin- und 3,3- biarylmorpholinderivate
MXPA03000644A (es) Nuevos derivados de indol y uso como medicamentos.
DE50002417D1 (de) 3-Amino-3-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
HUP0203839A3 (en) 4-phenyl-1-piperazinyl, -piperidinyl and -tetrahydropyridyl derivatives, pharmaceutical compositions containing them and their use
HUP0004981A3 (en) Cosmetic composition containing an aminophenol derivative, its use and process for dissolving aminophenol derivatives
DE60144456D1 (de) DibenzoÄb,fÜazepin-Derivate und ihre Herstellung
PL344345A1 (en) Platinum complex, its preparation and therapeutic application
HUP0400154A3 (en) Heterocondesated benzoxazepine and benzoxathiazepine derivatives, their use and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1173187

Country of ref document: EP

EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee