DE60002395D1 - Metalloproteaseinhibitoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen - Google Patents

Metalloproteaseinhibitoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Info

Publication number
DE60002395D1
DE60002395D1 DE60002395T DE60002395T DE60002395D1 DE 60002395 D1 DE60002395 D1 DE 60002395D1 DE 60002395 T DE60002395 T DE 60002395T DE 60002395 T DE60002395 T DE 60002395T DE 60002395 D1 DE60002395 D1 DE 60002395D1
Authority
DE
Germany
Prior art keywords
preparation
compositions containing
pharmaceutical compositions
heteroaryl
metalloprotease inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60002395T
Other languages
English (en)
Other versions
DE60002395T2 (de
Inventor
Nanteuil Guillaume De
Alain Benoist
Jacqueline Bonnet
Massimo Sabatini
Ghanem Atassi
Alain Pierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of DE60002395D1 publication Critical patent/DE60002395D1/de
Application granted granted Critical
Publication of DE60002395T2 publication Critical patent/DE60002395T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DE60002395T 1999-07-01 2000-06-30 Metalloproteaseinhibitoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen Expired - Fee Related DE60002395T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9908448 1999-07-01
FR9908448A FR2795730B1 (fr) 1999-07-01 1999-07-01 Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
DE60002395D1 true DE60002395D1 (de) 2003-06-05
DE60002395T2 DE60002395T2 (de) 2004-04-08

Family

ID=9547562

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60002395T Expired - Fee Related DE60002395T2 (de) 1999-07-01 2000-06-30 Metalloproteaseinhibitoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Country Status (22)

Country Link
US (1) US6339092B1 (de)
EP (1) EP1065209B1 (de)
JP (1) JP3330583B2 (de)
KR (1) KR100472521B1 (de)
CN (1) CN1147492C (de)
AT (1) ATE239021T1 (de)
AU (1) AU770168B2 (de)
BR (1) BR0002265A (de)
CA (1) CA2313302C (de)
DE (1) DE60002395T2 (de)
DK (1) DK1065209T3 (de)
EA (1) EA002527B1 (de)
ES (1) ES2198262T3 (de)
FR (1) FR2795730B1 (de)
HK (1) HK1034968A1 (de)
HU (1) HUP0002554A3 (de)
NO (1) NO20003431L (de)
NZ (1) NZ505522A (de)
PL (1) PL341134A1 (de)
PT (1) PT1065209E (de)
SI (1) SI1065209T1 (de)
ZA (1) ZA200003310B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003016248A2 (en) * 2001-08-17 2003-02-27 Bristol-Myers Squibb Company Patent Department Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or tnf-$g(a) converting enzyme (tace)
DE102005002500A1 (de) * 2005-01-19 2006-07-27 Sanofi-Aventis Deutschland Gmbh Tetrahydrofuranderivate als Inhibitoren von Matrix-Metalloproteinasen
US20110034526A1 (en) * 2007-12-21 2011-02-10 Wyeth Llc Benzimidazole Compounds
KR100962022B1 (ko) 2010-01-12 2010-06-08 (주) 유니크코리아엔아이 정전용량형 압력센서 및 그 제조방법
AU2014230816B9 (en) * 2013-03-14 2016-12-15 Glaxosmithkline Intellectual Property (No.2) Limited Furopyridines as bromodomain inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2748026B1 (fr) * 1996-04-26 1998-06-05 Adir Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE19719817A1 (de) * 1997-05-13 1998-11-19 Hoechst Ag Substituierte 6- und 7-Aminotetrahydroisochinolincarbonsäuren
JP2003524572A (ja) * 1997-08-04 2003-08-19 アムジエン・インコーポレーテツド ヒドロキサム酸置換縮合複素環メタロプロテイナーゼ阻害剤

Also Published As

Publication number Publication date
DK1065209T3 (da) 2003-08-25
PL341134A1 (en) 2001-01-02
CN1147492C (zh) 2004-04-28
ZA200003310B (en) 2001-01-25
NO20003431L (no) 2001-01-02
SI1065209T1 (en) 2003-08-31
KR100472521B1 (ko) 2005-03-08
ATE239021T1 (de) 2003-05-15
EP1065209A1 (de) 2001-01-03
AU4378400A (en) 2001-01-04
US6339092B1 (en) 2002-01-15
JP2001039983A (ja) 2001-02-13
EP1065209B1 (de) 2003-05-02
FR2795730A1 (fr) 2001-01-05
NO20003431D0 (no) 2000-06-30
HUP0002554A3 (en) 2002-12-28
HK1034968A1 (en) 2001-11-09
KR20010039689A (ko) 2001-05-15
HUP0002554A2 (hu) 2002-04-29
EA002527B1 (ru) 2002-06-27
CN1290703A (zh) 2001-04-11
CA2313302C (fr) 2004-06-15
DE60002395T2 (de) 2004-04-08
AU770168B2 (en) 2004-02-12
NZ505522A (en) 2001-12-21
JP3330583B2 (ja) 2002-09-30
FR2795730B1 (fr) 2001-08-31
ES2198262T3 (es) 2004-02-01
EA200000598A1 (ru) 2001-02-26
BR0002265A (pt) 2001-03-13
CA2313302A1 (fr) 2001-01-01
PT1065209E (pt) 2003-08-29
HU0002554D0 (en) 2000-08-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee