ZA200003310B - Metalloprotease inhibitors, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Metalloprotease inhibitors, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA200003310B
ZA200003310B ZA200003310A ZA200003310A ZA200003310B ZA 200003310 B ZA200003310 B ZA 200003310B ZA 200003310 A ZA200003310 A ZA 200003310A ZA 200003310 A ZA200003310 A ZA 200003310A ZA 200003310 B ZA200003310 B ZA 200003310B
Authority
ZA
South Africa
Prior art keywords
preparation
compositions containing
pharmaceutical compositions
heteroaryl
metalloprotease inhibitors
Prior art date
Application number
ZA200003310A
Other languages
English (en)
Inventor
Guillaume De Nanteuil
Alain Benoist
Jacqueline Bonnet
Massimo Sabatini
Ghanem Atassi
Alain Pierre
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA200003310B publication Critical patent/ZA200003310B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
ZA200003310A 1999-07-01 2000-06-30 Metalloprotease inhibitors, a process for their preparation and pharmaceutical compositions containing them. ZA200003310B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9908448A FR2795730B1 (fr) 1999-07-01 1999-07-01 Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA200003310B true ZA200003310B (en) 2001-01-25

Family

ID=9547562

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200003310A ZA200003310B (en) 1999-07-01 2000-06-30 Metalloprotease inhibitors, a process for their preparation and pharmaceutical compositions containing them.

Country Status (22)

Country Link
US (1) US6339092B1 (xx)
EP (1) EP1065209B1 (xx)
JP (1) JP3330583B2 (xx)
KR (1) KR100472521B1 (xx)
CN (1) CN1147492C (xx)
AT (1) ATE239021T1 (xx)
AU (1) AU770168B2 (xx)
BR (1) BR0002265A (xx)
CA (1) CA2313302C (xx)
DE (1) DE60002395T2 (xx)
DK (1) DK1065209T3 (xx)
EA (1) EA002527B1 (xx)
ES (1) ES2198262T3 (xx)
FR (1) FR2795730B1 (xx)
HK (1) HK1034968A1 (xx)
HU (1) HUP0002554A3 (xx)
NO (1) NO20003431L (xx)
NZ (1) NZ505522A (xx)
PL (1) PL341134A1 (xx)
PT (1) PT1065209E (xx)
SI (1) SI1065209T1 (xx)
ZA (1) ZA200003310B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770647B2 (en) * 2001-08-17 2004-08-03 Bristol-Myers Squibb Pharma Company Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
DE102005002500A1 (de) 2005-01-19 2006-07-27 Sanofi-Aventis Deutschland Gmbh Tetrahydrofuranderivate als Inhibitoren von Matrix-Metalloproteinasen
US20110034526A1 (en) * 2007-12-21 2011-02-10 Wyeth Llc Benzimidazole Compounds
KR100962022B1 (ko) 2010-01-12 2010-06-08 (주) 유니크코리아엔아이 정전용량형 압력센서 및 그 제조방법
JP6280573B2 (ja) * 2013-03-14 2018-02-14 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ ブロモドメイン阻害薬としてのフロピリジン

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2748026B1 (fr) * 1996-04-26 1998-06-05 Adir Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE19719817A1 (de) * 1997-05-13 1998-11-19 Hoechst Ag Substituierte 6- und 7-Aminotetrahydroisochinolincarbonsäuren
AU8766498A (en) * 1997-08-04 1999-02-22 Amgen, Inc. Hydroxamic acid substituted fused heterocyclic metalloproteinase inhibitors

Also Published As

Publication number Publication date
HU0002554D0 (en) 2000-08-28
HUP0002554A3 (en) 2002-12-28
JP2001039983A (ja) 2001-02-13
NZ505522A (en) 2001-12-21
EA200000598A1 (ru) 2001-02-26
EP1065209A1 (fr) 2001-01-03
HUP0002554A2 (hu) 2002-04-29
BR0002265A (pt) 2001-03-13
DK1065209T3 (da) 2003-08-25
FR2795730A1 (fr) 2001-01-05
AU4378400A (en) 2001-01-04
EA002527B1 (ru) 2002-06-27
EP1065209B1 (fr) 2003-05-02
PL341134A1 (en) 2001-01-02
CN1290703A (zh) 2001-04-11
KR20010039689A (ko) 2001-05-15
PT1065209E (pt) 2003-08-29
SI1065209T1 (en) 2003-08-31
KR100472521B1 (ko) 2005-03-08
AU770168B2 (en) 2004-02-12
CN1147492C (zh) 2004-04-28
DE60002395D1 (de) 2003-06-05
DE60002395T2 (de) 2004-04-08
NO20003431D0 (no) 2000-06-30
HK1034968A1 (en) 2001-11-09
US6339092B1 (en) 2002-01-15
NO20003431L (no) 2001-01-02
CA2313302A1 (fr) 2001-01-01
ATE239021T1 (de) 2003-05-15
JP3330583B2 (ja) 2002-09-30
CA2313302C (fr) 2004-06-15
FR2795730B1 (fr) 2001-08-31
ES2198262T3 (es) 2004-02-01

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