DE59607840D1 - Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen - Google Patents

Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen

Info

Publication number
DE59607840D1
DE59607840D1 DE59607840T DE59607840T DE59607840D1 DE 59607840 D1 DE59607840 D1 DE 59607840D1 DE 59607840 T DE59607840 T DE 59607840T DE 59607840 T DE59607840 T DE 59607840T DE 59607840 D1 DE59607840 D1 DE 59607840D1
Authority
DE
Germany
Prior art keywords
glycoproteins
glycosylation
bioavailability
characterizing
pct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59607840T
Other languages
English (en)
Inventor
Peter Hermentin
Reinhild Witzel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PETER HERMENTIN, DE
Original Assignee
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Priority to DE59607840T priority Critical patent/DE59607840D1/de
Application granted granted Critical
Publication of DE59607840D1 publication Critical patent/DE59607840D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE59607840T 1995-07-26 1996-05-30 Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen Expired - Lifetime DE59607840D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE59607840T DE59607840D1 (de) 1995-07-26 1996-05-30 Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19527054A DE19527054A1 (de) 1995-07-26 1995-07-26 Verfahren zur Charakterisierung der Glycosylierung von Glycoproteinen sowie zur in-vitro Bestimmung der Bioverfügbarkeit von Glycoproteinen
DE59607840T DE59607840D1 (de) 1995-07-26 1996-05-30 Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen
PCT/EP1996/002319 WO1997005490A1 (de) 1995-07-26 1996-05-30 Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen

Publications (1)

Publication Number Publication Date
DE59607840D1 true DE59607840D1 (de) 2001-11-08

Family

ID=7767674

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19527054A Withdrawn DE19527054A1 (de) 1995-07-26 1995-07-26 Verfahren zur Charakterisierung der Glycosylierung von Glycoproteinen sowie zur in-vitro Bestimmung der Bioverfügbarkeit von Glycoproteinen
DE59607840T Expired - Lifetime DE59607840D1 (de) 1995-07-26 1996-05-30 Verfahren zur charakterisierung der glycosylierung von glycoproteinen sowie zur in-vitro bestimmung der bioverfügbarkeit von glycoproteinen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19527054A Withdrawn DE19527054A1 (de) 1995-07-26 1995-07-26 Verfahren zur Charakterisierung der Glycosylierung von Glycoproteinen sowie zur in-vitro Bestimmung der Bioverfügbarkeit von Glycoproteinen

Country Status (13)

Country Link
US (1) US6096555A (de)
EP (1) EP0843821B1 (de)
JP (1) JP3631495B2 (de)
KR (1) KR19990035943A (de)
AT (1) ATE206524T1 (de)
AU (1) AU6003296A (de)
CA (1) CA2227743C (de)
DE (2) DE19527054A1 (de)
DK (1) DK0843821T3 (de)
ES (1) ES2162652T3 (de)
NO (1) NO980276L (de)
PT (1) PT843821E (de)
WO (1) WO1997005490A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020144310A1 (en) * 2000-01-28 2002-10-03 Lightfoot David A. Isolated polynucleotides and polypeptides relating to loci underlying resistance to soybean cyst nematode and soybean sudden death syndrome and methods employing same
US20030096281A1 (en) * 2001-09-14 2003-05-22 Ganesh Venkataraman Methods of making glycomolecules with enhanced activities and uses thereof
KR100982922B1 (ko) * 2002-01-17 2010-09-20 론자 바이올로직스 피엘씨 단백질을 생산할 수 있으며 무글루타민 배지에서 성장할 수있는 글루타민-요구성 인간세포
EP1587408A4 (de) * 2002-12-20 2007-09-05 Momenta Pharmaceuticals Inc Glycan-marker zur diagnose und überwachung von erkrankungen
JP4077339B2 (ja) * 2003-03-06 2008-04-16 独立行政法人科学技術振興機構 高等植物の糖リン酸の網羅的分析法
DE102005050580A1 (de) * 2005-10-21 2007-04-26 Siegfried Biologics Gmbh Verfahren zur Charakterisierung der Qualität von Sialoglycoproteinen über eine Isoformenzahl I und dessen Verwendung
EP2358731B1 (de) * 2008-12-19 2016-03-09 Momenta Pharmaceuticals, Inc. Verfahren bezüglich modifizierter glykane
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
US9170249B2 (en) 2011-03-12 2015-10-27 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing N-glycans in glycoprotein products
US20160145589A1 (en) 2011-06-24 2016-05-26 Green Cross Corporation Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
KR101380740B1 (ko) * 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
WO2014186310A1 (en) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins

Also Published As

Publication number Publication date
DK0843821T3 (da) 2002-01-28
ES2162652T3 (es) 2002-01-01
NO980276D0 (no) 1998-01-21
PT843821E (pt) 2002-03-28
KR19990035943A (ko) 1999-05-25
JP2000503109A (ja) 2000-03-14
CA2227743A1 (en) 1997-02-13
AU6003296A (en) 1997-02-26
CA2227743C (en) 2008-01-29
EP0843821A1 (de) 1998-05-27
US6096555A (en) 2000-08-01
EP0843821B1 (de) 2001-10-04
WO1997005490A1 (de) 1997-02-13
MX9800690A (es) 1998-09-30
NO980276L (no) 1998-01-21
ATE206524T1 (de) 2001-10-15
JP3631495B2 (ja) 2005-03-23
DE19527054A1 (de) 1997-01-30

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Legal Events

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8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, 65929 FRANKFURT,

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Ref document number: 843821

Country of ref document: EP

Owner name: PETER HERMENTIN, DE

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Effective date: 20120918