DE69725611D1 - Nicht-Nukleotid verknüpfende Reagentien - Google Patents

Nicht-Nukleotid verknüpfende Reagentien

Info

Publication number
DE69725611D1
DE69725611D1 DE69725611T DE69725611T DE69725611D1 DE 69725611 D1 DE69725611 D1 DE 69725611D1 DE 69725611 T DE69725611 T DE 69725611T DE 69725611 T DE69725611 T DE 69725611T DE 69725611 D1 DE69725611 D1 DE 69725611D1
Authority
DE
Germany
Prior art keywords
pct
reagents
nucleotide
linking reagents
nucleotide linking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69725611T
Other languages
English (en)
Other versions
DE69725611T2 (de
Inventor
Su George Sheng-Hui
Siva Iyer
K Aggarwal
L Kalra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOGENEX LAB SAN RAMON
Biogenex Laboratories Inc
Original Assignee
BIOGENEX LAB SAN RAMON
Biogenex Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOGENEX LAB SAN RAMON, Biogenex Laboratories Inc filed Critical BIOGENEX LAB SAN RAMON
Publication of DE69725611D1 publication Critical patent/DE69725611D1/de
Application granted granted Critical
Publication of DE69725611T2 publication Critical patent/DE69725611T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE69725611T 1996-05-15 1997-05-15 Nicht-Nukleotid verknüpfende Reagentien Expired - Fee Related DE69725611T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64782096A 1996-05-15 1996-05-15
US647820 1996-05-15
PCT/US1997/009094 WO1997043451A1 (en) 1996-05-15 1997-05-15 Non-nucleotide linking reagents

Publications (2)

Publication Number Publication Date
DE69725611D1 true DE69725611D1 (de) 2003-11-20
DE69725611T2 DE69725611T2 (de) 2004-07-29

Family

ID=24598396

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69725611T Expired - Fee Related DE69725611T2 (de) 1996-05-15 1997-05-15 Nicht-Nukleotid verknüpfende Reagentien

Country Status (8)

Country Link
US (1) US6130323A (de)
EP (1) EP0954606B1 (de)
JP (1) JP2001509784A (de)
AT (1) ATE252158T1 (de)
AU (1) AU733647B2 (de)
CA (1) CA2253969A1 (de)
DE (1) DE69725611T2 (de)
WO (1) WO1997043451A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000028326A1 (fr) * 1998-11-06 2000-05-18 Iatron Laboratories, Inc. Nouveaux complexes contenant de l'avidine reticulee, procede analytique dans lequel on utilise de l'avidine reticulee, reactifs et kits d'analyse
CA2417986C (en) 2000-08-11 2013-11-26 University Of Utah Research Foundation Single-labeled oligonucleotide probes
US7560231B2 (en) * 2002-12-20 2009-07-14 Roche Molecular Systems, Inc. Mannitol and glucitol derivatives
WO2004089295A2 (en) * 2003-04-01 2004-10-21 Chromagen, Inc. Homogeneous and heterogeneous assay methods using nucleation centers and novel covalent chemistries for the rapid measurement of phosphorylation and de-phosphorylation
CA2463719A1 (en) * 2003-04-05 2004-10-05 F. Hoffmann-La Roche Ag Nucleotide analogs with six membered rings
EP1502958A1 (de) * 2003-08-01 2005-02-02 Roche Diagnostics GmbH Neues Format zur Detektion von Heissstart- und Echtzeit-Polymerasekettenreaktion
EP1700922B1 (de) 2005-03-10 2016-08-24 Roche Diagnostics GmbH 3-Substituierte 5-Nitroindolderivate und diese enthaltende markierte Oligonukleotidsonden
ES2332139T3 (es) 2005-11-23 2010-01-27 F. Hoffmann-La Roche Ag Polinucleotidos con mimetico de fosfato.
US7759470B2 (en) 2006-02-20 2010-07-20 Roche Diagnostics Operations, Inc. Labeling reagent
WO2008143849A2 (en) 2007-05-14 2008-11-27 Historx, Inc. Compartment segregation by pixel characterization using image data clustering
US7907271B2 (en) 2007-06-15 2011-03-15 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
CN102165489B (zh) 2008-09-16 2015-11-25 赫斯托克斯公司 生物标志物表达的可再现量化
WO2011034605A2 (en) 2009-09-16 2011-03-24 Genentech, Inc. Coiled coil and/or tether containing protein complexes and uses thereof
TW201138821A (en) 2010-03-26 2011-11-16 Roche Glycart Ag Bispecific antibodies
CA2817928C (en) 2010-12-23 2019-10-01 Michael Gerg Detection of a posttranslationally modified polypeptide by a bi-valent binding agent
JP5766296B2 (ja) 2010-12-23 2015-08-19 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
MX2014009565A (es) 2012-02-10 2014-11-10 Genentech Inc Anticuerpos monocatenarios y otros heteromultimeros.
WO2014001325A1 (en) 2012-06-27 2014-01-03 F. Hoffmann-La Roche Ag Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
ES2597228T3 (es) 2012-06-27 2017-01-17 F. Hoffmann-La Roche Ag Procedimiento para la selección y la producción de entidades de objetivación, como dianas, altamente selectivas y multiespecíficas, personalizadas, las cuales contienen por lo menos dos entidades de unión diferentes, y utilización de éstas
PL3227332T3 (pl) 2014-12-03 2020-06-15 F. Hoffmann-La Roche Ag Wielospecyficzne przeciwciała
IL291323B2 (en) * 2016-07-15 2023-09-01 Am Chemicals Llc Solid non-nucleoside supports and phosphoramidite building blocks for oligonucleotide synthesis
CN108219513B (zh) * 2018-03-14 2019-11-08 青岛科技大学 一种羧基荧光素的制备方法

Also Published As

Publication number Publication date
ATE252158T1 (de) 2003-11-15
AU3146597A (en) 1997-12-05
JP2001509784A (ja) 2001-07-24
WO1997043451A1 (en) 1997-11-20
EP0954606A1 (de) 1999-11-10
AU733647B2 (en) 2001-05-17
US6130323A (en) 2000-10-10
EP0954606B1 (de) 2003-10-15
EP0954606A4 (de) 1999-12-22
CA2253969A1 (en) 1997-11-20
DE69725611T2 (de) 2004-07-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee