DE59505877D1 - Mikro-Fluiddiode - Google Patents

Mikro-Fluiddiode

Info

Publication number
DE59505877D1
DE59505877D1 DE59505877T DE59505877T DE59505877D1 DE 59505877 D1 DE59505877 D1 DE 59505877D1 DE 59505877 T DE59505877 T DE 59505877T DE 59505877 T DE59505877 T DE 59505877T DE 59505877 D1 DE59505877 D1 DE 59505877D1
Authority
DE
Germany
Prior art keywords
micro
capillaries
fluid
flow
etched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE59505877T
Other languages
English (en)
Inventor
Minh Tan Dr Pham
Steffen Dr Howitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Howitz Steffen Dr 01159 Dresden De
Original Assignee
Forschungszentrum Juelich GmbH
Forschungszentrum Dresden Rossendorf eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich GmbH, Forschungszentrum Dresden Rossendorf eV filed Critical Forschungszentrum Juelich GmbH
Application granted granted Critical
Publication of DE59505877D1 publication Critical patent/DE59505877D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
    • F15C4/00—Circuit elements characterised by their special functions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/2224—Structure of body of device
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87571—Multiple inlet with single outlet
    • Y10T137/87652—With means to promote mixing or combining of plural fluids
DE59505877T 1994-02-17 1995-02-09 Mikro-Fluiddiode Expired - Fee Related DE59505877D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4405005A DE4405005A1 (de) 1994-02-17 1994-02-17 Mikro-Fluiddiode

Publications (1)

Publication Number Publication Date
DE59505877D1 true DE59505877D1 (de) 1999-06-17

Family

ID=6510442

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4405005A Withdrawn DE4405005A1 (de) 1994-02-17 1994-02-17 Mikro-Fluiddiode
DE59505877T Expired - Fee Related DE59505877D1 (de) 1994-02-17 1995-02-09 Mikro-Fluiddiode

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4405005A Withdrawn DE4405005A1 (de) 1994-02-17 1994-02-17 Mikro-Fluiddiode

Country Status (7)

Country Link
US (1) US5730187A (de)
EP (1) EP0672835B1 (de)
JP (1) JP3786421B2 (de)
AT (1) ATE180044T1 (de)
DE (2) DE4405005A1 (de)
DK (1) DK0672835T3 (de)
WO (1) WO1995022696A1 (de)

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DE19530886C1 (de) * 1995-08-11 1996-10-02 Inst Bioprozess Analysenmesst Vorrichtung zur sterilen Entnahme von Proben über eine Filtermembran
DE19611270A1 (de) * 1996-03-22 1997-09-25 Gesim Ges Fuer Silizium Mikros Mikromischer zur Handhabung kleinster Flüssigkeitsmengen
US6033544A (en) * 1996-10-11 2000-03-07 Sarnoff Corporation Liquid distribution system
US5964997A (en) * 1997-03-21 1999-10-12 Sarnoff Corporation Balanced asymmetric electronic pulse patterns for operating electrode-based pumps
US6117396A (en) * 1998-02-18 2000-09-12 Orchid Biocomputer, Inc. Device for delivering defined volumes
JP2981547B1 (ja) * 1998-07-02 1999-11-22 農林水産省食品総合研究所長 クロスフロー型マイクロチャネル装置及び同装置を用いたエマルションの生成または分離方法
JP3012608B1 (ja) * 1998-09-17 2000-02-28 農林水産省食品総合研究所長 マイクロチャネル装置及び同装置を用いたエマルションの製造方法
US6591852B1 (en) 1998-10-13 2003-07-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
BR9914554A (pt) * 1998-10-13 2001-06-26 Biomicro Systems Inc Componentes de circuito fluido com base em dinâmica dos fluidos passiva
US6601613B2 (en) 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6637463B1 (en) 1998-10-13 2003-10-28 Biomicro Systems, Inc. Multi-channel microfluidic system design with balanced fluid flow distribution
US6360775B1 (en) 1998-12-23 2002-03-26 Agilent Technologies, Inc. Capillary fluid switch with asymmetric bubble chamber
US6561208B1 (en) * 2000-04-14 2003-05-13 Nanostream, Inc. Fluidic impedances in microfluidic system
US6481453B1 (en) * 2000-04-14 2002-11-19 Nanostream, Inc. Microfluidic branch metering systems and methods
US6296452B1 (en) 2000-04-28 2001-10-02 Agilent Technologies, Inc. Microfluidic pumping
US6615856B2 (en) * 2000-08-04 2003-09-09 Biomicro Systems, Inc. Remote valving for microfluidic flow control
JP3511238B2 (ja) 2000-10-13 2004-03-29 独立行政法人食品総合研究所 マイクロスフィアの製造方法および製造装置
EP1334279A1 (de) 2000-11-06 2003-08-13 Nanostream, Inc. Unidirektional-durchfluss-mikrofluidkomponenten
US6649078B2 (en) 2000-12-06 2003-11-18 The Regents Of The University Of California Thin film capillary process and apparatus
US20020186263A1 (en) * 2001-06-07 2002-12-12 Nanostream, Inc. Microfluidic fraction collectors
US7179423B2 (en) 2001-06-20 2007-02-20 Cytonome, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US20020197733A1 (en) * 2001-06-20 2002-12-26 Coventor, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US20020195343A1 (en) * 2001-06-20 2002-12-26 Coventor, Inc. Microfabricated separation device employing a virtual wall for interfacing fluids
US20030015425A1 (en) * 2001-06-20 2003-01-23 Coventor Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US7211442B2 (en) * 2001-06-20 2007-05-01 Cytonome, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
EP1314479A3 (de) * 2001-11-24 2004-03-24 GeSIM Gesellschaft für Silizium-Mikrosysteme mbH Vorrichtung für den Transfer flüssiger Proben
US6932502B2 (en) * 2002-05-01 2005-08-23 Hewlett-Packard Development Company, L.P. Mixing apparatus
US20050032238A1 (en) * 2003-08-07 2005-02-10 Nanostream, Inc. Vented microfluidic separation devices and methods
KR100540143B1 (ko) * 2003-12-22 2006-01-10 한국전자통신연구원 미소 유체 제어소자 및 미소 유체의 제어 방법
JP4520166B2 (ja) * 2004-02-02 2010-08-04 独立行政法人農業・食品産業技術総合研究機構 樹脂製マイクロチャネル基板及びその製造方法
AU2005272546B2 (en) * 2004-08-12 2010-11-11 Yuji Kikuchi Micro channel array
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US9040305B2 (en) * 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
US7572640B2 (en) * 2004-09-28 2009-08-11 Singulex, Inc. Method for highly sensitive detection of single protein molecules labeled with fluorescent moieties
WO2006047757A1 (en) * 2004-10-26 2006-05-04 Massachusetts Institute Of Technology Systems and methods for transferring a fluid sample
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
ES2550004T3 (es) 2006-04-04 2015-11-03 Singulex, Inc. Sistema de alta sensibilidad y métodos de análisis de la troponina
EP3156799B1 (de) 2006-04-04 2024-01-24 Novilux, LLC Analysator und verfahren zur hochempfindlichen detektion von analyten
US8524173B2 (en) * 2006-09-01 2013-09-03 Tosoh Corporation Microchannel structure and fine-particle production method using the same
US8931501B2 (en) * 2006-12-20 2015-01-13 Applied Biosystems, Llc Devices and methods for flow control in microfluidic structures
US20090087860A1 (en) * 2007-08-24 2009-04-02 Todd John A Highly sensitive system and methods for analysis of prostate specific antigen (psa)
WO2009117033A2 (en) 2007-12-19 2009-09-24 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
CN102016552A (zh) * 2008-03-05 2011-04-13 神谷来克斯公司 用于分子的高灵敏性检测的方法和组合物
GB2464183A (en) * 2008-09-19 2010-04-14 Singulex Inc Sandwich assay
AU2010259022B2 (en) * 2009-06-08 2016-05-12 Singulex, Inc. Highly sensitive biomarker panels
WO2011140484A1 (en) 2010-05-06 2011-11-10 Singulex, Inc Methods for diagnosing, staging, predicting risk for developing and identifying treatment responders for rheumatoid arthritis
CN103240023B (zh) * 2013-05-09 2015-01-07 四川大学 一种微手术刀触发液滴融合的方法
US11085039B2 (en) 2016-12-12 2021-08-10 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
CN110268108B (zh) 2016-12-12 2022-09-06 埃克切拉生物科学公司 用于使用微毛细管阵列进行筛选的方法和系统
JP7208902B2 (ja) 2016-12-30 2023-01-19 エクセラ・バイオサイエンシーズ・インコーポレイテッド マルチステージサンプル回収システム
US20180304266A1 (en) * 2017-04-24 2018-10-25 miDiagnostics NV Channel and a capillary trigger valve comprising the same
WO2021144396A1 (en) 2020-01-17 2021-07-22 F. Hoffmann-La Roche Ag Microfluidic device and method for automated split-pool synthesis
JP2023510961A (ja) 2020-01-22 2023-03-15 エフ． ホフマン－ラ ロシュ アーゲー マイクロ流体ビーズトラッピング装置および次世代配列決定ライブラリ調製のための方法
EP4228793A1 (de) 2020-10-15 2023-08-23 Kapa Biosystems, Inc. Elektrophoretische vorrichtungen und verfahren zur vorbereitung einer sequenzierungsbibliothek der nächsten generation

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US3777344A (en) * 1969-05-28 1973-12-11 Cava Ind Method of fabricating fluidic elements by assembling together a plurality of plastic strips
US3865136A (en) * 1971-04-29 1975-02-11 Eke Verschuur Oil/water pipeline inlet with oil supply via a large chamber
US4027407A (en) * 1975-11-24 1977-06-07 Kiss Sandor G Jet flow alternator
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Also Published As

Publication number Publication date
ATE180044T1 (de) 1999-05-15
US5730187A (en) 1998-03-24
JPH09509466A (ja) 1997-09-22
EP0672835A1 (de) 1995-09-20
WO1995022696A1 (de) 1995-08-24
DK0672835T3 (da) 1999-11-29
DE4405005A1 (de) 1995-08-24
JP3786421B2 (ja) 2006-06-14
EP0672835B1 (de) 1999-05-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HOWITZ, STEFFEN, DR., 01159 DRESDEN, DE

8339 Ceased/non-payment of the annual fee