DE59409179D1 - Chinolin-Verbindungen als Leukotriene Antagonisten - Google Patents
Chinolin-Verbindungen als Leukotriene AntagonistenInfo
- Publication number
- DE59409179D1 DE59409179D1 DE59409179T DE59409179T DE59409179D1 DE 59409179 D1 DE59409179 D1 DE 59409179D1 DE 59409179 T DE59409179 T DE 59409179T DE 59409179 T DE59409179 T DE 59409179T DE 59409179 D1 DE59409179 D1 DE 59409179D1
- Authority
- DE
- Germany
- Prior art keywords
- quinoline compounds
- antagonists
- leukotrienes
- leukotrienes antagonists
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93810645 | 1993-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE59409179D1 true DE59409179D1 (de) | 2000-04-13 |
Family
ID=8215029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE59409179T Expired - Lifetime DE59409179D1 (de) | 1993-09-10 | 1994-09-01 | Chinolin-Verbindungen als Leukotriene Antagonisten |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5508408A (enExample) |
| JP (1) | JP3652721B2 (enExample) |
| KR (1) | KR950008483A (enExample) |
| CN (1) | CN1054845C (enExample) |
| AT (1) | ATE190307T1 (enExample) |
| AU (1) | AU683481B2 (enExample) |
| CA (1) | CA2131644C (enExample) |
| CZ (1) | CZ284006B6 (enExample) |
| DE (1) | DE59409179D1 (enExample) |
| ES (1) | ES2144501T3 (enExample) |
| FI (1) | FI944120A7 (enExample) |
| HU (1) | HUT70556A (enExample) |
| IL (1) | IL110864A0 (enExample) |
| NO (1) | NO301639B1 (enExample) |
| NZ (1) | NZ264420A (enExample) |
| PH (1) | PH31094A (enExample) |
| PT (1) | PT643045E (enExample) |
| SK (1) | SK107394A3 (enExample) |
| TW (1) | TW249802B (enExample) |
| ZA (1) | ZA946957B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ515087A (en) | 1999-04-28 | 2003-11-28 | Aventis Pharma Gmbh | Tri-aryl acid derivatives as PPAR receptor ligands |
| IT1320162B1 (it) | 2000-02-09 | 2003-11-18 | Rotta Research Lab | Derivati della tirosina ad attivita' anti leucotrienica, procedimentoper la loro preparazione e loro uso farmaceutico. |
| US6531494B1 (en) * | 2001-08-29 | 2003-03-11 | Pharmacia Corporation | Gem-substituted αvβ3 antagonists |
| US7056917B2 (en) * | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5109009A (en) * | 1985-03-08 | 1992-04-28 | Leo Pharmaceutical Products Ltd. | Quinoline and pyridine compounds and inhibition of 5-lipoxygenases therewith |
| IE58870B1 (en) * | 1985-03-08 | 1993-11-17 | Leo Pharm Prod Ltd | Pyridine derivatives |
| US4962203A (en) * | 1985-06-18 | 1990-10-09 | Merck Frost Canada, Inc. | 2-substituted quinolines useful as leukotriene antagonists |
| ATE68789T1 (de) * | 1985-10-16 | 1991-11-15 | Merck Frosst Canada Inc | 2-substituierte chinoline. |
| EP0219307A3 (en) * | 1985-10-16 | 1987-10-14 | Merck Frosst Canada Inc. | 2-substituted quinolines |
| JPS62142168A (ja) * | 1985-10-16 | 1987-06-25 | Mitsubishi Chem Ind Ltd | チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤 |
| JPS62145049A (ja) * | 1985-12-18 | 1987-06-29 | Mitsubishi Chem Ind Ltd | アミノスチリル化合物及びそれを有効成分とするロイコトリエンきつ抗剤 |
| JPS63258854A (ja) * | 1987-04-16 | 1988-10-26 | Mitsubishi Kasei Corp | カルボキシスチレン誘導体およびそれを有効成分とする薬剤 |
| ES2052825T3 (es) * | 1988-07-15 | 1994-07-16 | Hoffmann La Roche | Derivados de cicloalquiltiazol. |
| JPH02275857A (ja) * | 1989-01-13 | 1990-11-09 | Yoshitomi Pharmaceut Ind Ltd | ピリジン誘導体 |
| CN1078151A (zh) * | 1993-01-01 | 1993-11-10 | 周礼伯 | 天然药物成分的蚕药 |
| CN1050999C (zh) * | 1993-02-16 | 2000-04-05 | 胡祖良 | 抗病毒性蚕病的蚕药 |
-
1994
- 1994-08-10 US US08/288,537 patent/US5508408A/en not_active Expired - Lifetime
- 1994-08-13 TW TW083107418A patent/TW249802B/zh active
- 1994-08-23 PH PH48841A patent/PH31094A/en unknown
- 1994-09-01 DE DE59409179T patent/DE59409179D1/de not_active Expired - Lifetime
- 1994-09-01 ES ES94810504T patent/ES2144501T3/es not_active Expired - Lifetime
- 1994-09-01 PT PT94810504T patent/PT643045E/pt unknown
- 1994-09-01 AT AT94810504T patent/ATE190307T1/de not_active IP Right Cessation
- 1994-09-01 AU AU71617/94A patent/AU683481B2/en not_active Ceased
- 1994-09-05 IL IL11086494A patent/IL110864A0/xx unknown
- 1994-09-07 FI FI944120A patent/FI944120A7/fi not_active Application Discontinuation
- 1994-09-08 CA CA002131644A patent/CA2131644C/en not_active Expired - Fee Related
- 1994-09-08 SK SK1073-94A patent/SK107394A3/sk unknown
- 1994-09-08 HU HU9402585A patent/HUT70556A/hu unknown
- 1994-09-08 CZ CZ942187A patent/CZ284006B6/cs not_active IP Right Cessation
- 1994-09-08 NZ NZ264420A patent/NZ264420A/en unknown
- 1994-09-09 NO NO943336A patent/NO301639B1/no unknown
- 1994-09-09 CN CN94115157A patent/CN1054845C/zh not_active Expired - Fee Related
- 1994-09-09 KR KR1019940022688A patent/KR950008483A/ko not_active Withdrawn
- 1994-09-09 ZA ZA946957A patent/ZA946957B/xx unknown
- 1994-09-12 JP JP21747594A patent/JP3652721B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW249802B (enExample) | 1995-06-21 |
| ATE190307T1 (de) | 2000-03-15 |
| CA2131644C (en) | 2007-04-24 |
| US5508408A (en) | 1996-04-16 |
| AU683481B2 (en) | 1997-11-13 |
| CZ218794A3 (en) | 1995-03-15 |
| CN1054845C (zh) | 2000-07-26 |
| CN1105991A (zh) | 1995-08-02 |
| NO943336L (no) | 1995-03-13 |
| SK107394A3 (en) | 1995-05-10 |
| NZ264420A (en) | 1996-06-25 |
| IL110864A0 (en) | 1994-11-28 |
| CZ284006B6 (cs) | 1998-07-15 |
| ZA946957B (en) | 1995-04-18 |
| AU7161794A (en) | 1995-03-23 |
| CA2131644A1 (en) | 1995-03-11 |
| HUT70556A (en) | 1995-10-30 |
| JP3652721B2 (ja) | 2005-05-25 |
| HU9402585D0 (en) | 1994-11-28 |
| NO301639B1 (no) | 1997-11-24 |
| FI944120A7 (fi) | 1995-03-11 |
| KR950008483A (ko) | 1995-04-17 |
| PH31094A (en) | 1998-02-05 |
| JPH07179426A (ja) | 1995-07-18 |
| FI944120A0 (fi) | 1994-09-07 |
| NO943336D0 (no) | 1994-09-09 |
| ES2144501T3 (es) | 2000-06-16 |
| PT643045E (pt) | 2000-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |