DE4223688C1 - - Google Patents

Info

Publication number
DE4223688C1
DE4223688C1 DE4223688A DE4223688A DE4223688C1 DE 4223688 C1 DE4223688 C1 DE 4223688C1 DE 4223688 A DE4223688 A DE 4223688A DE 4223688 A DE4223688 A DE 4223688A DE 4223688 C1 DE4223688 C1 DE 4223688C1
Authority
DE
Germany
Prior art keywords
diphenyl
dimethylaminoethyl
hydrochloride
ester hydrochloride
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE4223688A
Other languages
German (de)
English (en)
Inventor
Michael Dr. O-8300 Pirna De Heschel
Steffen Dr. O-8051 Dresden De Scheithauer
Rosemarie O-8019 Dresden De Otto
Christian Dr. O-8053 Dresden De Starke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apogepha Arzneimittel O-8019 Dresden De GmbH
Original Assignee
Apogepha Arzneimittel O-8019 Dresden De GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19914133785 external-priority patent/DE4133785A1/de
Application filed by Apogepha Arzneimittel O-8019 Dresden De GmbH filed Critical Apogepha Arzneimittel O-8019 Dresden De GmbH
Priority to DE4223688A priority Critical patent/DE4223688C1/de
Priority to DE59205394T priority patent/DE59205394D1/de
Priority to DK92117108.8T priority patent/DK0537608T3/da
Priority to AT92117108T priority patent/ATE134362T1/de
Priority to ES92117108T priority patent/ES2084237T3/es
Priority to EP92117108A priority patent/EP0537608B1/de
Publication of DE4223688C1 publication Critical patent/DE4223688C1/de
Application granted granted Critical
Priority to GR960401067T priority patent/GR3019688T3/el
Priority to HK98105758A priority patent/HK1006454A1/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/10—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to an acyclic carbon atom of a carbon skeleton containing rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE4223688A 1991-10-11 1992-07-17 Expired - Fee Related DE4223688C1 ( )

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE4223688A DE4223688C1 ( ) 1991-10-11 1992-07-17
ES92117108T ES2084237T3 (es) 1991-10-11 1992-10-07 Procedimiento para fabricacion tecnica de clorhidrato de ester de (2-dimetilamino-etilo) de acido 2,2-difenil-2-(2-etil-butoxi)-acetico.
DK92117108.8T DK0537608T3 (da) 1991-10-11 1992-10-07 Fremgangsmåde til teknisk fremstilling af 2,2-diphenyl-2-(2-ethylbutoxy)-eddikesyre- (2-dimethylaminoethyl)-ester-hydrochlorid
AT92117108T ATE134362T1 (de) 1991-10-11 1992-10-07 Verfahren zur technischen herstellung von 2,2- diphenyl-2-(2-ethyl-butoxy)-essigsäure-(2- dimethylamino-ethyl)-ester-hydrochlorid
DE59205394T DE59205394D1 (de) 1991-10-11 1992-10-07 Verfahren zur technischen Herstellung von 2,2-Diphenyl-2-(2-ethyl-butoxy)-essigsäure-(2-dimethylamino-ethyl)-ester-hydrochlorid
EP92117108A EP0537608B1 (de) 1991-10-11 1992-10-07 Verfahren zur technischen Herstellung von 2,2-Diphenyl-2-(2-ethyl-butoxy)-essigsäure-(2-dimethylamino-ethyl)-ester-hydrochlorid
GR960401067T GR3019688T3 (en) 1991-10-11 1996-04-19 Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester, hydrochloride
HK98105758A HK1006454A1 (en) 1991-10-11 1998-06-19 Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester hydrochloride

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19914133785 DE4133785A1 (de) 1991-10-11 1991-10-11 Verfahren zur technischen herstellung von 2,2-diphenyl-2-(2-ethylbutoxy)-essigsaeure-(2-dimethylaminoethyl)-ester-hydrochlorid
DE4223688A DE4223688C1 ( ) 1991-10-11 1992-07-17

Publications (1)

Publication Number Publication Date
DE4223688C1 true DE4223688C1 ( ) 1993-07-22

Family

ID=25908163

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4223688A Expired - Fee Related DE4223688C1 ( ) 1991-10-11 1992-07-17
DE59205394T Expired - Lifetime DE59205394D1 (de) 1991-10-11 1992-10-07 Verfahren zur technischen Herstellung von 2,2-Diphenyl-2-(2-ethyl-butoxy)-essigsäure-(2-dimethylamino-ethyl)-ester-hydrochlorid

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59205394T Expired - Lifetime DE59205394D1 (de) 1991-10-11 1992-10-07 Verfahren zur technischen Herstellung von 2,2-Diphenyl-2-(2-ethyl-butoxy)-essigsäure-(2-dimethylamino-ethyl)-ester-hydrochlorid

Country Status (7)

Country Link
EP (1) EP0537608B1 ( )
AT (1) ATE134362T1 ( )
DE (2) DE4223688C1 ( )
DK (1) DK0537608T3 ( )
ES (1) ES2084237T3 ( )
GR (1) GR3019688T3 ( )
HK (1) HK1006454A1 ( )

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113061095B (zh) * 2021-03-10 2022-01-11 宁波三生生物科技股份有限公司 一种盐酸地那维林的合成方法
CN113979873B (zh) * 2021-11-25 2024-02-13 齐鲁动物保健品有限公司 一种盐酸地那维林的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2394770A (en) * 1942-02-21 1946-02-12 American Cyanamid Co Alcoholysis of alkamine esters of diaryl hydroxyacetic acids
DE1036270B (de) * 1953-11-23 1958-08-14 Asal Fabrik Biolog Und Pharmaz Verfahren zur Herstellung von ª‡,ª‡-diphenyl-ª‡-oxy-essigsauren Salzen von ª‡,ª‡-Diphenyl-ª‡-oxy-essig-saeure-(ª‰-dialkylaminoaethyl)-estern
DD106643A1 ( ) * 1973-07-12 1974-06-20
EP0180416A3 (en) * 1984-10-30 1986-11-20 Takeda Chemical Industries, Ltd. Benzoic acid analogues and their production

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS ERMITTELT *

Also Published As

Publication number Publication date
ES2084237T3 (es) 1996-05-01
GR3019688T3 (en) 1996-07-31
EP0537608A2 (de) 1993-04-21
EP0537608A3 (en) 1993-06-16
DE59205394D1 (de) 1996-03-28
DK0537608T3 (da) 1996-05-20
ATE134362T1 (de) 1996-03-15
EP0537608B1 (de) 1996-02-21
HK1006454A1 (en) 1999-02-26

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