HK1006454A1 - Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester hydrochloride - Google Patents

Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester hydrochloride

Info

Publication number
HK1006454A1
HK1006454A1 HK98105758A HK98105758A HK1006454A1 HK 1006454 A1 HK1006454 A1 HK 1006454A1 HK 98105758 A HK98105758 A HK 98105758A HK 98105758 A HK98105758 A HK 98105758A HK 1006454 A1 HK1006454 A1 HK 1006454A1
Authority
HK
Hong Kong
Prior art keywords
diphenyl
hydrochloride
ethyl
ester hydrochloride
acetic acid
Prior art date
Application number
HK98105758A
Other languages
English (en)
Inventor
Michael Heschel
Steffen Schelthauer
Rosemarie Otto
Christian Starke
Original Assignee
Apogepha Arzneimittel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19914133785 external-priority patent/DE4133785A1/de
Application filed by Apogepha Arzneimittel Gmbh filed Critical Apogepha Arzneimittel Gmbh
Publication of HK1006454A1 publication Critical patent/HK1006454A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/10—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to an acyclic carbon atom of a carbon skeleton containing rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK98105758A 1991-10-11 1998-06-19 Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester hydrochloride HK1006454A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19914133785 DE4133785A1 (de) 1991-10-11 1991-10-11 Verfahren zur technischen herstellung von 2,2-diphenyl-2-(2-ethylbutoxy)-essigsaeure-(2-dimethylaminoethyl)-ester-hydrochlorid
DE4223688A DE4223688C1 (xx) 1991-10-11 1992-07-17

Publications (1)

Publication Number Publication Date
HK1006454A1 true HK1006454A1 (en) 1999-02-26

Family

ID=25908163

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98105758A HK1006454A1 (en) 1991-10-11 1998-06-19 Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester hydrochloride

Country Status (7)

Country Link
EP (1) EP0537608B1 (xx)
AT (1) ATE134362T1 (xx)
DE (2) DE4223688C1 (xx)
DK (1) DK0537608T3 (xx)
ES (1) ES2084237T3 (xx)
GR (1) GR3019688T3 (xx)
HK (1) HK1006454A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113061095B (zh) * 2021-03-10 2022-01-11 宁波三生生物科技股份有限公司 一种盐酸地那维林的合成方法
CN113979873B (zh) * 2021-11-25 2024-02-13 齐鲁动物保健品有限公司 一种盐酸地那维林的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2394770A (en) * 1942-02-21 1946-02-12 American Cyanamid Co Alcoholysis of alkamine esters of diaryl hydroxyacetic acids
DE1036270B (de) * 1953-11-23 1958-08-14 Asal Fabrik Biolog Und Pharmaz Verfahren zur Herstellung von ª‡,ª‡-diphenyl-ª‡-oxy-essigsauren Salzen von ª‡,ª‡-Diphenyl-ª‡-oxy-essig-saeure-(ª‰-dialkylaminoaethyl)-estern
DD106643A1 (xx) * 1973-07-12 1974-06-20
EP0180416A3 (en) * 1984-10-30 1986-11-20 Takeda Chemical Industries, Ltd. Benzoic acid analogues and their production

Also Published As

Publication number Publication date
ES2084237T3 (es) 1996-05-01
GR3019688T3 (en) 1996-07-31
EP0537608A2 (de) 1993-04-21
EP0537608A3 (en) 1993-06-16
DE59205394D1 (de) 1996-03-28
DK0537608T3 (da) 1996-05-20
ATE134362T1 (de) 1996-03-15
EP0537608B1 (de) 1996-02-21
DE4223688C1 (xx) 1993-07-22

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20061007