DE4042492C2 - Verwendung von 4,5-Di-n-hexylimidazol zur Herstellung von fungiziden Mitteln - Google Patents
Verwendung von 4,5-Di-n-hexylimidazol zur Herstellung von fungiziden MittelnInfo
- Publication number
- DE4042492C2 DE4042492C2 DE4042492A DE4042492A DE4042492C2 DE 4042492 C2 DE4042492 C2 DE 4042492C2 DE 4042492 A DE4042492 A DE 4042492A DE 4042492 A DE4042492 A DE 4042492A DE 4042492 C2 DE4042492 C2 DE 4042492C2
- Authority
- DE
- Germany
- Prior art keywords
- agar
- cpds
- hexylimidazole
- test
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title abstract 5
- 150000002460 imidazoles Chemical class 0.000 title 1
- SLJJAFUERCIEMU-UHFFFAOYSA-N 4,5-dihexyl-1h-imidazole Chemical compound CCCCCCC=1N=CNC=1CCCCCC SLJJAFUERCIEMU-UHFFFAOYSA-N 0.000 claims description 15
- 230000000855 fungicidal effect Effects 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 9
- 239000000417 fungicide Substances 0.000 abstract description 7
- 239000003755 preservative agent Substances 0.000 abstract description 5
- 239000003599 detergent Substances 0.000 abstract description 4
- 229910052736 halogen Inorganic materials 0.000 abstract description 2
- 150000002367 halogens Chemical class 0.000 abstract description 2
- 230000002335 preservative effect Effects 0.000 abstract description 2
- 238000005406 washing Methods 0.000 abstract description 2
- 239000002023 wood Substances 0.000 abstract description 2
- 241001251054 Formica truncorum Species 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 239000002543 antimycotic Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229920001817 Agar Polymers 0.000 description 22
- 239000008272 agar Substances 0.000 description 22
- 239000000126 substance Substances 0.000 description 13
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 11
- 238000012360 testing method Methods 0.000 description 10
- 230000002401 inhibitory effect Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000002768 Kirby-Bauer method Methods 0.000 description 5
- 238000009472 formulation Methods 0.000 description 5
- 230000002538 fungal effect Effects 0.000 description 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 4
- 239000002609 medium Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 229960000988 nystatin Drugs 0.000 description 3
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 241000282414 Homo sapiens Species 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- 239000006159 Sabouraud's agar Substances 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 description 2
- 229960004022 clotrimazole Drugs 0.000 description 2
- 239000007799 cork Substances 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 2
- 239000012449 sabouraud dextrose agar Substances 0.000 description 2
- 238000013207 serial dilution Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 229930195730 Aflatoxin Natural products 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 108010023063 Bacto-peptone Proteins 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241000223218 Fusarium Species 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 239000007836 KH2PO4 Substances 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 241000228143 Penicillium Species 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 240000003085 Quassia amara Species 0.000 description 1
- 208000035415 Reinfection Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000005409 aflatoxin Substances 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 230000000973 chemotherapeutic effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4042492A DE4042492C2 (de) | 1990-10-18 | 1990-10-18 | Verwendung von 4,5-Di-n-hexylimidazol zur Herstellung von fungiziden Mitteln |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19904033042 DE4033042A1 (de) | 1990-10-18 | 1990-10-18 | Verwendung von 4,5 - disubstituierten imidazolen zur herstellung von antimykotischen oder fungiziden mitteln |
| DE4042492A DE4042492C2 (de) | 1990-10-18 | 1990-10-18 | Verwendung von 4,5-Di-n-hexylimidazol zur Herstellung von fungiziden Mitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE4042492C2 true DE4042492C2 (de) | 1995-04-13 |
Family
ID=6416525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE4042492A Expired - Fee Related DE4042492C2 (de) | 1990-10-18 | 1990-10-18 | Verwendung von 4,5-Di-n-hexylimidazol zur Herstellung von fungiziden Mitteln |
| DE19904033042 Granted DE4033042A1 (de) | 1990-10-18 | 1990-10-18 | Verwendung von 4,5 - disubstituierten imidazolen zur herstellung von antimykotischen oder fungiziden mitteln |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19904033042 Granted DE4033042A1 (de) | 1990-10-18 | 1990-10-18 | Verwendung von 4,5 - disubstituierten imidazolen zur herstellung von antimykotischen oder fungiziden mitteln |
Country Status (1)
| Country | Link |
|---|---|
| DE (2) | DE4042492C2 (cg-RX-API-DMAC7.html) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3501286A (en) * | 1964-06-29 | 1970-03-17 | Shell Oil Co | Plant growth control |
| DE3212749A1 (de) * | 1982-04-06 | 1983-10-13 | Basf Ag, 6700 Ludwigshafen | Neue 5-substituierte 4-methylimidazole und verfahren zu ihrer herstellung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
-
1990
- 1990-10-18 DE DE4042492A patent/DE4042492C2/de not_active Expired - Fee Related
- 1990-10-18 DE DE19904033042 patent/DE4033042A1/de active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3501286A (en) * | 1964-06-29 | 1970-03-17 | Shell Oil Co | Plant growth control |
| DE3212749A1 (de) * | 1982-04-06 | 1983-10-13 | Basf Ag, 6700 Ludwigshafen | Neue 5-substituierte 4-methylimidazole und verfahren zu ihrer herstellung |
Non-Patent Citations (1)
| Title |
|---|
| Chem.-Abstr.:115(2)18563p * |
Also Published As
| Publication number | Publication date |
|---|---|
| DE4033042C2 (cg-RX-API-DMAC7.html) | 1993-05-13 |
| DE4033042A1 (de) | 1992-05-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69805697T3 (de) | Desinfizierende und fungizide Zusammensetzung auf der Basis von Peressigsäure und einem Aminoxid | |
| DE69923695T2 (de) | Topisch-dermale antimikrobielle zusammensetzungen | |
| EP0547727B1 (de) | Hautantiseptikum und Händedesinfektionsmittel | |
| DE68906231T2 (de) | Biozide Verbindungen. | |
| DE68906011T2 (de) | Chitosan enthaltendes kosmetisches praeparat. | |
| DE4439527A1 (de) | Verfahren zum Desinfizieren und Sterilisieren von verunreinigtem Material | |
| DE69503603T2 (de) | Synergistische antimikrobielle zusammensetzungen, die ein halogeniertes acetophenon und eine organische säure enthalten | |
| DE10224979A1 (de) | Synergistische Zubereitungen auf Basis von Gemischen von Glycerinether mit aromatischem Alkohol zur Bekämpfung von Mykobakterien | |
| CH639243A5 (de) | Mittel zur vertilgung von ektoparasiten und/oder zur abtoetung von deren eiern. | |
| DE3149008A1 (de) | Mikroben toetende, das wachstum von mikroben hemmendezusammensetzungen und deren verwendung | |
| DE69101925T2 (de) | Neue synergistische zusammensetzung von 2-(2-brom-2-nitroethenyl) furan und 2-brom-2-nitropropan-1,3- diol und verwendungen davon. | |
| DE2134332C3 (de) | 0-(N-Methylcarbamoyl)-carbäthoxychlorformaldoxim, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Mittel | |
| DE4042492C2 (de) | Verwendung von 4,5-Di-n-hexylimidazol zur Herstellung von fungiziden Mitteln | |
| DE2554587A1 (de) | Desinfektionsmittel | |
| AT519820B1 (de) | Zubereitung enthaltend wenigstens ein chemisches Fungizid sowie eine Aufbereitung enthaltend Aureobasidium pullulansstämme | |
| EP0119226B1 (de) | Verwendung eines mittels zur antimikrobiellen behandlung von lebens- und futtermitteln | |
| DE102011077432A1 (de) | Verwendung von Bispyridiniumalkanen zur Abtötung von Sporen | |
| DE69316623T2 (de) | Synergistische antimikrobielle zusammensetzung, die 2-(2-brom-2-nitroethenyl) furan enthält | |
| DE2320415C3 (de) | Verfahren zur Verhinderung der Schleimbildung in wäßrigen Zellstoffsuspensionen durch Anwendung keimtötender Mittel | |
| DD150144A5 (de) | Synergistisch wirksames fungizides mittel | |
| EP0059980A1 (de) | Verwendung eines antimikrobiell wirksamen Konservierungsmittels in Ophthalmica und Pflegemitteln für Kontaktlinsen | |
| DE3644473C2 (de) | Konservierte Haar- und Körperreinigungsmittel sowie Verwendung einer Konservierungsstoff-Kombination | |
| DD267420A1 (de) | Verfahren zur bekaempfung phytopathogener bodenpilze mit fungiziden und mikrobiellen antagonisten | |
| DE19508654A1 (de) | Verfahren und Mittel zum Desinfizieren von Oberflächen, die Tuberkulose verursachende Bakterien aufweist | |
| DE1642501C (de) | Neue biocide Zusammensetzungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| Q172 | Divided out of (supplement): |
Ref country code: DE Ref document number: 4033042 |
|
| 8110 | Request for examination paragraph 44 | ||
| AC | Divided out of |
Ref country code: DE Ref document number: 4033042 Format of ref document f/p: P |
|
| AC | Divided out of |
Ref country code: DE Ref document number: 4033042 Format of ref document f/p: P |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |