DE3888936D1 - Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. - Google Patents

Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.

Info

Publication number
DE3888936D1
DE3888936D1 DE88310246T DE3888936T DE3888936D1 DE 3888936 D1 DE3888936 D1 DE 3888936D1 DE 88310246 T DE88310246 T DE 88310246T DE 3888936 T DE3888936 T DE 3888936T DE 3888936 D1 DE3888936 D1 DE 3888936D1
Authority
DE
Germany
Prior art keywords
intermediates
production
macrolide antibiotics
anthelmintic effect
anthelmintic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88310246T
Other languages
English (en)
Other versions
DE3888936T2 (de
Inventor
Geoffrey Harold C O Beec Baker
Roderick John C O Beech Dorgan
David Owen C O Beecham Morgan
Rhona Mary C O Beecham P Banks
Simon Edward C O Blanchflower
Mark Edward C O Beecha Poulton
Peter Robin Shelley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878725679A external-priority patent/GB8725679D0/en
Priority claimed from GB888818374A external-priority patent/GB8818374D0/en
Priority claimed from GB888824763A external-priority patent/GB8824763D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE3888936D1 publication Critical patent/DE3888936D1/de
Publication of DE3888936T2 publication Critical patent/DE3888936T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pest Control & Pesticides (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE3888936T 1987-11-03 1988-11-01 Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. Expired - Fee Related DE3888936T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878725679A GB8725679D0 (en) 1987-11-03 1987-11-03 Compounds
GB888818374A GB8818374D0 (en) 1988-08-02 1988-08-02 Novel compounds
GB888824763A GB8824763D0 (en) 1988-10-21 1988-10-21 Novel compounds

Publications (2)

Publication Number Publication Date
DE3888936D1 true DE3888936D1 (de) 1994-05-11
DE3888936T2 DE3888936T2 (de) 1994-07-21

Family

ID=27263654

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3888936T Expired - Fee Related DE3888936T2 (de) 1987-11-03 1988-11-01 Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.

Country Status (4)

Country Link
US (1) US5055596A (de)
EP (1) EP0319142B1 (de)
JP (1) JP2854006B2 (de)
DE (1) DE3888936T2 (de)

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US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
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DK3172964T3 (da) 2011-09-12 2020-11-30 Boehringer Ingelheim Animal Health Usa Inc Parasitiske sammensætninger indeholdende et isoxazolinaktivstof, fremgangsmåde og anvendelser deraf
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
BR112014013371B1 (pt) 2011-12-02 2020-04-07 Merial Ltd formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
EP3216448B8 (de) 2012-02-06 2019-06-05 Boehringer Ingelheim Animal Health USA Inc. Parasitizide orale tiermedizinische zusammensetzungen mit systemisch wirkenden wirkstoffen, verfahren und verwendungen davon
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
CN104395295B (zh) 2012-04-20 2018-03-06 梅里亚有限公司 包含苯并咪唑衍生物的杀寄生物的组合物，其方法和用途
EP2922845B1 (de) 2012-11-20 2018-06-20 Merial, Inc. Anthelmintische verbindungen und zusammensetzungen und verfahren zur verwendung davon
PL2950795T3 (pl) 2013-01-31 2018-09-28 Merial, Inc. Sposób leczenia i wyleczenia leiszmaniozy z zastosowaniem feksinidazolu
CN105873925B (zh) 2013-11-01 2019-09-10 勃林格殷格翰动物保健美国公司 抗寄生物的和杀虫的异噁唑啉化合物
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
ES2842592T3 (es) 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
CA2952857A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
AU2015339096B2 (en) 2014-10-31 2018-08-02 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal composition comprising fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
KR102593069B1 (ko) 2015-04-08 2023-10-23 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 이속사졸린 활성제를 포함하는 서방형 주사 제형, 이의 방법 및 용도
ES2916216T3 (es) 2015-05-20 2022-06-29 Boehringer Ingelheim Animal Health Usa Inc Compuestos de depsipéptidos antihelmínticos
AU2016267047A1 (en) 2015-05-27 2017-12-21 Merial, Inc. Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
AU2017344097A1 (en) 2016-10-14 2019-05-02 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (de) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintische depsipeptidverbindungen
AU2018292285B2 (en) 2017-06-26 2023-05-25 Boehringer Ingelheim Animal Health USA Inc. Dual active parasiticidal granule compositions, methods and uses thereof
JP2020530850A (ja) 2017-08-14 2020-10-29 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺有害生物および殺寄生生物ピラゾール−イソキサゾリン化合物
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
EP3820870A1 (de) 2018-07-09 2021-05-19 Boehringer Ingelheim Animal Health USA Inc. Anthelminthische heterocyclische verbindungen
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
WO2020150032A1 (en) 2019-01-16 2020-07-23 Boehringer Ingelheim Animal Health USA Inc. Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
CN113507922A (zh) 2019-03-01 2021-10-15 勃林格殷格翰动物保健美国公司 可注射的氯舒隆组合物、其方法和用途
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
CN110526925B (zh) * 2019-07-16 2021-10-12 遵义市第一人民医院 一种25β-仲丁烯基-23β-异丁酰氧基米尔贝霉素衍生物的分离方法及其应用
JP2022541916A (ja) 2019-07-22 2022-09-28 インターベット インターナショナル ベー． フェー． ソフトチュアブル獣医学用投与形態
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Also Published As

Publication number Publication date
JP2854006B2 (ja) 1999-02-03
EP0319142A3 (en) 1989-10-25
EP0319142A2 (de) 1989-06-07
DE3888936T2 (de) 1994-07-21
EP0319142B1 (de) 1994-04-06
US5055596A (en) 1991-10-08
JPH01157985A (ja) 1989-06-21

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Legal Events

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8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER, INC. (N.D.GES.D. STAATES DELAWARE), NEW YO

8339 Ceased/non-payment of the annual fee