DE3887362T2 - Thymopentin-Retro-Inverso-Analoga und deren Fragmente, Verfahren zu deren Herstellung und so erhaltene Zwischenprodukte. - Google Patents

Thymopentin-Retro-Inverso-Analoga und deren Fragmente, Verfahren zu deren Herstellung und so erhaltene Zwischenprodukte.

Info

Publication number
DE3887362T2
DE3887362T2 DE88103699T DE3887362T DE3887362T2 DE 3887362 T2 DE3887362 T2 DE 3887362T2 DE 88103699 T DE88103699 T DE 88103699T DE 3887362 T DE3887362 T DE 3887362T DE 3887362 T2 DE3887362 T2 DE 3887362T2
Authority
DE
Germany
Prior art keywords
retro
inverto
intermediates
fragments
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88103699T
Other languages
English (en)
Other versions
DE3887362D1 (de
Inventor
Alessandro Sisto
Antonio Silvio Verdini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sclavo SpA
Eni Tecnologie SpA
Original Assignee
Sclavo SpA
Eniricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo SpA, Eniricerche SpA filed Critical Sclavo SpA
Publication of DE3887362D1 publication Critical patent/DE3887362D1/de
Application granted granted Critical
Publication of DE3887362T2 publication Critical patent/DE3887362T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE88103699T 1987-03-19 1988-03-09 Thymopentin-Retro-Inverso-Analoga und deren Fragmente, Verfahren zu deren Herstellung und so erhaltene Zwischenprodukte. Expired - Fee Related DE3887362T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8719763A IT1216908B (it) 1987-03-19 1987-03-19 Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.

Publications (2)

Publication Number Publication Date
DE3887362D1 DE3887362D1 (de) 1994-03-10
DE3887362T2 true DE3887362T2 (de) 1994-05-11

Family

ID=11161024

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88103699T Expired - Fee Related DE3887362T2 (de) 1987-03-19 1988-03-09 Thymopentin-Retro-Inverso-Analoga und deren Fragmente, Verfahren zu deren Herstellung und so erhaltene Zwischenprodukte.

Country Status (8)

Country Link
US (1) US5013723A (de)
EP (1) EP0282891B1 (de)
JP (1) JPS63250360A (de)
AT (1) ATE100816T1 (de)
CA (1) CA1315472C (de)
DE (1) DE3887362T2 (de)
ES (1) ES2061533T3 (de)
IT (1) IT1216908B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200506A (en) * 1987-03-19 1993-04-06 Eniricerche S.P.A. Process for preparing new thymopentin retro-inverso analogs and fragments thereof and the intermediates obtained therein
US5214052A (en) * 1987-07-28 1993-05-25 Mitsubishi Kasei Corporation Method for dissolving arginineamides and pharmaceutical compositions containing them
GB8807427D0 (en) * 1988-03-28 1988-05-05 National Biological Standards Board Peptides
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
IT1227908B (it) * 1988-12-23 1991-05-14 Eniricerche S P A Milano Sclav Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
US5218089A (en) * 1988-12-23 1993-06-08 Sclavo S.P.A. Retro-inverso analogues of thymopentin and the method for their synthesis
IT1241395B (it) * 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
BR9306984A (pt) 1992-08-27 1999-01-12 Deakin Res Ltd Análogo de antígeno de peptídeo de um antígeno de peptídeo nativo vacina anticorpo processo para vacinar um hospedeiro necessitando deste tratamento estojo diagnóstico processos para preparar um análogo de um antiígeno de um antígeno de peptídeo nativo para preparar uma vacina para analisar uma amostra para um antígeno de peptídeo nativo e para analisar uma amostra para um anticorpo
US5639729A (en) * 1993-08-26 1997-06-17 Immunobiology Research Institute, Inc. Tripeptides useful in immune and CNS therapy
IT1270882B (it) * 1993-10-05 1997-05-13 Isagro Srl Oligopeptidi ad attivita' fungicida
AUPM411994A0 (en) * 1994-02-25 1994-03-24 Deakin Research Limited Epitopes
RU2107692C1 (ru) 1995-06-07 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
RU2107691C1 (ru) 1995-03-02 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
US11975051B1 (en) 2022-07-12 2024-05-07 Siobhan Ellison Therapeutic peptides and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505853A (en) * 1983-11-18 1985-03-19 Ortho Pharmaceutical Corporation Enzyme-resistant immunomodulatory peptides
US4547489A (en) * 1984-06-11 1985-10-15 Ortho Pharmaceutical Corporation Conformationally restricted thymopentin-like compounds
US4629723A (en) * 1984-06-27 1986-12-16 Ortho Pharmaceutical Corporation Potent thymopentin analogs
HUT46044A (en) * 1986-11-21 1988-09-28 Richter Gedeon Vegyeszet Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same

Also Published As

Publication number Publication date
EP0282891B1 (de) 1994-01-26
JPS63250360A (ja) 1988-10-18
DE3887362D1 (de) 1994-03-10
ATE100816T1 (de) 1994-02-15
CA1315472C (en) 1993-03-30
IT8719763A0 (it) 1987-03-19
EP0282891A2 (de) 1988-09-21
US5013723A (en) 1991-05-07
IT1216908B (it) 1990-03-14
EP0282891A3 (en) 1990-05-23
ES2061533T3 (es) 1994-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee