ATE100816T1 - Thymopentin-retro-inverso-analoga und deren fragmente, verfahren zu deren herstellung und so erhaltene zwischenprodukte. - Google Patents

Thymopentin-retro-inverso-analoga und deren fragmente, verfahren zu deren herstellung und so erhaltene zwischenprodukte.

Info

Publication number
ATE100816T1
ATE100816T1 AT88103699T AT88103699T ATE100816T1 AT E100816 T1 ATE100816 T1 AT E100816T1 AT 88103699 T AT88103699 T AT 88103699T AT 88103699 T AT88103699 T AT 88103699T AT E100816 T1 ATE100816 T1 AT E100816T1
Authority
AT
Austria
Prior art keywords
thymopentin
retro
fragments
processes
preparation
Prior art date
Application number
AT88103699T
Other languages
English (en)
Inventor
Alessandro Sisto
Antonio Silvio Verdini
Original Assignee
Eniricerche Spa
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa, Sclavo Spa filed Critical Eniricerche Spa
Application granted granted Critical
Publication of ATE100816T1 publication Critical patent/ATE100816T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT88103699T 1987-03-19 1988-03-09 Thymopentin-retro-inverso-analoga und deren fragmente, verfahren zu deren herstellung und so erhaltene zwischenprodukte. ATE100816T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8719763A IT1216908B (it) 1987-03-19 1987-03-19 Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
EP88103699A EP0282891B1 (de) 1987-03-19 1988-03-09 Thymopentin-Retro-Inverso-Analoga und deren Fragmente, Verfahren zu deren Herstellung und so erhaltene Zwischenprodukte

Publications (1)

Publication Number Publication Date
ATE100816T1 true ATE100816T1 (de) 1994-02-15

Family

ID=11161024

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88103699T ATE100816T1 (de) 1987-03-19 1988-03-09 Thymopentin-retro-inverso-analoga und deren fragmente, verfahren zu deren herstellung und so erhaltene zwischenprodukte.

Country Status (8)

Country Link
US (1) US5013723A (de)
EP (1) EP0282891B1 (de)
JP (1) JPS63250360A (de)
AT (1) ATE100816T1 (de)
CA (1) CA1315472C (de)
DE (1) DE3887362T2 (de)
ES (1) ES2061533T3 (de)
IT (1) IT1216908B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200506A (en) * 1987-03-19 1993-04-06 Eniricerche S.P.A. Process for preparing new thymopentin retro-inverso analogs and fragments thereof and the intermediates obtained therein
US5214052A (en) * 1987-07-28 1993-05-25 Mitsubishi Kasei Corporation Method for dissolving arginineamides and pharmaceutical compositions containing them
GB8807427D0 (en) * 1988-03-28 1988-05-05 National Biological Standards Board Peptides
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
IT1227908B (it) * 1988-12-23 1991-05-14 Eniricerche S P A Milano Sclav Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
US5218089A (en) * 1988-12-23 1993-06-08 Sclavo S.P.A. Retro-inverso analogues of thymopentin and the method for their synthesis
IT1241395B (it) * 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
KR950702839A (ko) 1992-08-27 1995-08-23 스티븐 딕 레트로, 인버소-, 및 레트로- 인버소 합성 펩티드 유사체(retro-, inverso-, and retro-inverso synthetic peptide analogues)
US5639729A (en) * 1993-08-26 1997-06-17 Immunobiology Research Institute, Inc. Tripeptides useful in immune and CNS therapy
IT1270882B (it) * 1993-10-05 1997-05-13 Isagro Srl Oligopeptidi ad attivita' fungicida
AUPM411994A0 (en) * 1994-02-25 1994-03-24 Deakin Research Limited Epitopes
RU2107692C1 (ru) 1995-06-07 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
RU2107691C1 (ru) 1995-03-02 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
US11975051B1 (en) 2022-07-12 2024-05-07 Siobhan Ellison Therapeutic peptides and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505853A (en) * 1983-11-18 1985-03-19 Ortho Pharmaceutical Corporation Enzyme-resistant immunomodulatory peptides
US4547489A (en) * 1984-06-11 1985-10-15 Ortho Pharmaceutical Corporation Conformationally restricted thymopentin-like compounds
US4629723A (en) * 1984-06-27 1986-12-16 Ortho Pharmaceutical Corporation Potent thymopentin analogs
HUT46044A (en) * 1986-11-21 1988-09-28 Richter Gedeon Vegyeszet Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same

Also Published As

Publication number Publication date
US5013723A (en) 1991-05-07
ES2061533T3 (es) 1994-12-16
EP0282891B1 (de) 1994-01-26
EP0282891A3 (en) 1990-05-23
EP0282891A2 (de) 1988-09-21
IT1216908B (it) 1990-03-14
JPS63250360A (ja) 1988-10-18
CA1315472C (en) 1993-03-30
DE3887362D1 (de) 1994-03-10
DE3887362T2 (de) 1994-05-11
IT8719763A0 (it) 1987-03-19

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