JPS646294A - Novel peptide derivative - Google Patents

Novel peptide derivative

Info

Publication number
JPS646294A
JPS646294A JP62241647A JP24164787A JPS646294A JP S646294 A JPS646294 A JP S646294A JP 62241647 A JP62241647 A JP 62241647A JP 24164787 A JP24164787 A JP 24164787A JP S646294 A JPS646294 A JP S646294A
Authority
JP
Japan
Prior art keywords
group
peptide
formula
amino
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62241647A
Other languages
Japanese (ja)
Inventor
Tsuneo Ishiguro
Arahiko Eguchi
Nobuaki Kato
Toshiyuki Matsuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP62241647A priority Critical patent/JPS646294A/en
Publication of JPS646294A publication Critical patent/JPS646294A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

NEW MATERIAL:The compound of formula I (A is Arg or Lys; B is Tyr, Phe, etc.; C is Asn or Gln; m, n and k are 0 or 1; X is Leu, Ala-Leu, group of formula II, etc.; Y is Thr, Thr-Arg, group of formula III, etc.; R<1> is H, alkyl, aryl, acyl, etc.; R<2> is OH, amino, alkyl-substituted amino, etc.). USE:A remedy for cardiopathy, hypertension, thrombosis, etc., and an antitumor agent. PREPARATION:The objective peptide of formula I can be produced e.g. by (1) reacting a p-methylbenzhydrylamine hydrochloride polymer used as an insoluble polymer carrier with an amino group-protected amino acid according to the amino acid sequence of the peptide, (2) removing the protecting group of the amino group, (3) repeating the above operations and (4) treating the resultant peptide polymer with HF to effect the removal of the whole protecting groups and the separation of the peptide from the polymer.
JP62241647A 1987-02-09 1987-09-25 Novel peptide derivative Pending JPS646294A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62241647A JPS646294A (en) 1987-02-09 1987-09-25 Novel peptide derivative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2776487 1987-02-09
JP62241647A JPS646294A (en) 1987-02-09 1987-09-25 Novel peptide derivative

Publications (1)

Publication Number Publication Date
JPS646294A true JPS646294A (en) 1989-01-10

Family

ID=26365739

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62241647A Pending JPS646294A (en) 1987-02-09 1987-09-25 Novel peptide derivative

Country Status (1)

Country Link
JP (1) JPS646294A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022467A1 (en) * 1993-03-29 1994-10-13 University Of Cincinnati Analogs of peptide yy and uses thereof
US5670482A (en) * 1992-06-20 1997-09-23 Glaxo Wellcome Inc. Neuropeptide Y antagonists

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670482A (en) * 1992-06-20 1997-09-23 Glaxo Wellcome Inc. Neuropeptide Y antagonists
WO1994022467A1 (en) * 1993-03-29 1994-10-13 University Of Cincinnati Analogs of peptide yy and uses thereof
US5604203A (en) * 1993-03-29 1997-02-18 University Of Cincinnati Analogs of peptide YY and uses thereof
AU685803B2 (en) * 1993-03-29 1998-01-29 University Of Cincinnati, The Analogs of peptide YY and uses thereof

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