DE3885090T2 - Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil. - Google Patents

Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil.

Info

Publication number
DE3885090T2
DE3885090T2 DE88908588T DE3885090T DE3885090T2 DE 3885090 T2 DE3885090 T2 DE 3885090T2 DE 88908588 T DE88908588 T DE 88908588T DE 3885090 T DE3885090 T DE 3885090T DE 3885090 T2 DE3885090 T2 DE 3885090T2
Authority
DE
Germany
Prior art keywords
hepatitic
ethyluracil
arabinofuranosyl
deoxy
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88908588T
Other languages
English (en)
Other versions
DE3885090D1 (de
Inventor
Jack Fox
Kyoichi Watanabe
Carlos Lopez
Christian Trepo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Sloan Kettering Institute for Cancer Research
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Sloan Kettering Institute for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Sloan Kettering Institute for Cancer Research filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of DE3885090D1 publication Critical patent/DE3885090D1/de
Application granted granted Critical
Publication of DE3885090T2 publication Critical patent/DE3885090T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE88908588T 1987-09-03 1988-09-02 Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil. Expired - Fee Related DE3885090T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9244687A 1987-09-03 1987-09-03
PCT/US1988/003035 WO1989001776A1 (en) 1987-09-03 1988-09-02 Composition and method for treating hepatitis virus infections using 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil

Publications (2)

Publication Number Publication Date
DE3885090D1 DE3885090D1 (de) 1993-11-25
DE3885090T2 true DE3885090T2 (de) 1994-05-11

Family

ID=22233256

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88908588T Expired - Fee Related DE3885090T2 (de) 1987-09-03 1988-09-02 Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil.

Country Status (10)

Country Link
EP (1) EP0338042B1 (de)
JP (1) JPH02500524A (de)
KR (1) KR970011386B1 (de)
AU (1) AU2487688A (de)
CA (1) CA1328865C (de)
DE (1) DE3885090T2 (de)
ES (1) ES2014042A6 (de)
IL (1) IL87646A (de)
PT (1) PT88420B (de)
WO (1) WO1989001776A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
EA008609B1 (ru) * 1998-02-25 2007-06-29 Эмори Юниверсити 2'-фторнуклеозиды
PT1411954E (pt) * 2000-10-18 2011-03-16 Pharmasset Inc Nucleosídeos modificados para o tratamento de infecções virais e proliferação celular anormal

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211733A (en) * 1978-12-26 1980-07-08 Chang Shih Chih Gas-liquid mixing process and apparatus
HU198393B (en) * 1984-03-06 1989-10-30 Sloan Kettering Inst Cancer Process for production of medical composition suitable for treatment of hepatitis containing as active substance derivatives of piramidin-nucleoside
US4666892A (en) * 1984-03-06 1987-05-19 Sloan-Kettering Memorial Cancer Center Method and composition for hepatitis treatment with pyrimidine nucleoside compounds

Also Published As

Publication number Publication date
ES2014042A6 (es) 1990-06-16
JPH02500524A (ja) 1990-02-22
PT88420A (pt) 1989-07-31
CA1328865C (en) 1994-04-26
DE3885090D1 (de) 1993-11-25
PT88420B (pt) 1993-12-31
EP0338042A1 (de) 1989-10-25
EP0338042B1 (de) 1993-10-20
AU2487688A (en) 1989-03-31
WO1989001776A1 (en) 1989-03-09
EP0338042A4 (en) 1990-09-26
IL87646A (en) 1994-07-31
KR890701112A (ko) 1989-12-19
KR970011386B1 (ko) 1997-07-10

Similar Documents

Publication Publication Date Title
DE69010893T2 (de) Verfahren zur behandlung von koks sowie löschen desselben.
DE69232565T2 (de) Verfahren zur behandlung von lungenerkrankungen mit uridin-triphosphaten
DE3888205T2 (de) Verfahren zur behandlung von lungenaffektionen und zubereitungen dafür.
DE3674308D1 (de) Biozide zusammensetzungund verfahren zur behandlung von wasser.
DE69108178D1 (de) Befestigungseinrichtung und Verfahren zur Bearbeitung von Rotoren.
DE3877834D1 (de) Verfahren zur behandlung von abgasen.
DE3677400D1 (de) Verfahren zur behandlung von knochenersatz-implantaten.
DE3860919D1 (de) Verbesserte detergens-bleichmittelzusammensetzung und verfahren zur reinigung von geweben.
DE3781535D1 (de) Verfahren und vorrichtung zur aseptischen behandlung von lebensmitteln.
DE3885733D1 (de) Verfahren zur befreiung von zellgemischen und geweben von unerwünschten populationen.
DE3787543D1 (de) Verfahren zur herstellung von 6,13-dihydrochinacridonen und chinacridonen.
DE3765137D1 (de) Verfahren und zusammensetzung zur vorbeugung und behandlung von virus-infektionen.
DE3885090T2 (de) Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil.
DE68903208T2 (de) Verfahren zur thermischen behandlung von laktoferrin.
DE69006509D1 (de) Verfahren zur behandlung von häuten.
DE3484138D1 (de) Vorrichtung und verfahren zur behandlung von leiterplatten.
DE3777022D1 (de) Verfahren und praeparat zur inaktivierung von viren.
DE68907914T2 (de) Verfahren zur behandlung von brandwunden.
ATE96029T1 (de) Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5- ethyluracil.
DE69214139D1 (de) Verfahren zur behandlung von mit feuchtigkeit enthaltenden feinkohlen
DE3880072D1 (de) N-phenyl-2,2,6,6-tetrahalogencyclohexanimin und verfahren zur herstellung von derivaten des 2,2,6,6-tetrahalogencyclohexanimins und von derivaten des 2,6-dihalogenanilins.
DE68906651D1 (de) Zusammensetzung und verfahren zur behandlung von metalloberflaechen.
DE3762300D1 (de) Verfahren und zusammensetzung zur ueberwachung und bekaempfung von pityogenes chalcographus.
DE68905602T2 (de) Verfahren zur behandlung von titanstrukturen.
DE3885277D1 (de) Verfahren zur Behandlung von schrumpffähigen Fasern.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8339 Ceased/non-payment of the annual fee