IL87646A - Preparation for the treatment of hepatitis virus containing 1 -) 2 '- Deoxy - 2' - Fluoro - Beta - B - D - Arabino - Furanozil (- 5 - Orcil - Google Patents
Preparation for the treatment of hepatitis virus containing 1 -) 2 '- Deoxy - 2' - Fluoro - Beta - B - D - Arabino - Furanozil (- 5 - OrcilInfo
- Publication number
- IL87646A IL87646A IL8764688A IL8764688A IL87646A IL 87646 A IL87646 A IL 87646A IL 8764688 A IL8764688 A IL 8764688A IL 8764688 A IL8764688 A IL 8764688A IL 87646 A IL87646 A IL 87646A
- Authority
- IL
- Israel
- Prior art keywords
- feau
- day
- fmau
- virus
- whv
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9244687A | 1987-09-03 | 1987-09-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL87646A true IL87646A (en) | 1994-07-31 |
Family
ID=22233256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL8764688A IL87646A (en) | 1987-09-03 | 1988-09-01 | Preparation for the treatment of hepatitis virus containing 1 -) 2 '- Deoxy - 2' - Fluoro - Beta - B - D - Arabino - Furanozil (- 5 - Orcil |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0338042B1 (de) |
JP (1) | JPH02500524A (de) |
KR (1) | KR970011386B1 (de) |
AU (1) | AU2487688A (de) |
CA (1) | CA1328865C (de) |
DE (1) | DE3885090T2 (de) |
ES (1) | ES2014042A6 (de) |
IL (1) | IL87646A (de) |
PT (1) | PT88420B (de) |
WO (1) | WO1989001776A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6599887B2 (en) | 1988-07-07 | 2003-07-29 | Chimerix, Inc. | Methods of treating viral infections using antiviral liponucleotides |
US6252060B1 (en) | 1988-07-07 | 2001-06-26 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
US5817638A (en) * | 1988-07-07 | 1998-10-06 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
US5587362A (en) * | 1994-01-28 | 1996-12-24 | Univ. Of Ga Research Foundation | L-nucleosides |
CN100349913C (zh) * | 1998-02-25 | 2007-11-21 | 埃莫里大学 | 2′-氟代核苷 |
PT1411954E (pt) * | 2000-10-18 | 2011-03-16 | Pharmasset Inc | Nucleosídeos modificados para o tratamento de infecções virais e proliferação celular anormal |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4211733A (en) * | 1978-12-26 | 1980-07-08 | Chang Shih Chih | Gas-liquid mixing process and apparatus |
US4666892A (en) * | 1984-03-06 | 1987-05-19 | Sloan-Kettering Memorial Cancer Center | Method and composition for hepatitis treatment with pyrimidine nucleoside compounds |
AU575918B2 (en) * | 1984-03-06 | 1988-08-11 | Sloan-Kettering Institute For Cancer Research | Hepatitis treatment with pyrimidine nucleoside compounds |
-
1988
- 1988-09-01 IL IL8764688A patent/IL87646A/en not_active IP Right Cessation
- 1988-09-02 PT PT88420A patent/PT88420B/pt not_active IP Right Cessation
- 1988-09-02 EP EP88908588A patent/EP0338042B1/de not_active Expired - Lifetime
- 1988-09-02 CA CA000576381A patent/CA1328865C/en not_active Expired - Fee Related
- 1988-09-02 AU AU24876/88A patent/AU2487688A/en not_active Abandoned
- 1988-09-02 WO PCT/US1988/003035 patent/WO1989001776A1/en active IP Right Grant
- 1988-09-02 JP JP63507929A patent/JPH02500524A/ja active Pending
- 1988-09-02 ES ES8802716A patent/ES2014042A6/es not_active Expired - Lifetime
- 1988-09-02 KR KR1019890700795A patent/KR970011386B1/ko not_active IP Right Cessation
- 1988-09-02 DE DE88908588T patent/DE3885090T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2014042A6 (es) | 1990-06-16 |
DE3885090D1 (de) | 1993-11-25 |
EP0338042A4 (en) | 1990-09-26 |
KR970011386B1 (ko) | 1997-07-10 |
JPH02500524A (ja) | 1990-02-22 |
CA1328865C (en) | 1994-04-26 |
PT88420B (pt) | 1993-12-31 |
PT88420A (pt) | 1989-07-31 |
DE3885090T2 (de) | 1994-05-11 |
EP0338042A1 (de) | 1989-10-25 |
KR890701112A (ko) | 1989-12-19 |
AU2487688A (en) | 1989-03-31 |
WO1989001776A1 (en) | 1989-03-09 |
EP0338042B1 (de) | 1993-10-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5246924A (en) | Method for treating hepatitis B virus infections using 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil | |
Öberg | Antiviral effects of phosphonoformate (PFA, foscarnet sodium) | |
US7094770B2 (en) | 3′-or 2′-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections | |
CA1336820C (en) | Fluorinated nucleosides and process for treating retrovirus infections therewith | |
White et al. | A TIBO derivative, R82913, is a potent inhibitor of HIV-1 reverse transcriptase with heteropolymer templates | |
EP0145739B1 (de) | Neue antivirale agenzien | |
EP0277151B1 (de) | Medizinische verwendung von nukleosiden | |
IE860677L (en) | Antiviral formulation | |
Boezi | The antiherpesvirus action of phosphonoacetate | |
Zoulim et al. | 2', 3'-dideoxy-beta-L-5-fluorocytidine inhibits duck hepatitis B virus reverse transcription and suppresses viral DNA synthesis in hepatocytes, both in vitro and in vivo | |
WO1984004748A2 (en) | Novel antiviral agents | |
WO2003080078A1 (en) | Treatment of pre-core hepatitis b virus mutant infections | |
US5039667A (en) | Antiviral therapy for hepatitis B with 2',3'-dideoxypurine nucleosides | |
Schinazi et al. | Activities of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and its metabolites against herpes simplex virus types 1 and 2 in cell culture and in mice infected intracerebrally with herpes simplex virus type 2 | |
EP0302760B1 (de) | Antivirale Therapie gegen Hepatitis B mit 2',3'-Didesoxynucleosiden | |
EP0338042B1 (de) | Zusammensetzung und verfahren zur behandlung von hepatitisvirusinfektionen unter verwendung von 1-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)-5-ethyluracil | |
Prusoff et al. | Physical and biological consequences of incorporation of antiviral agents into virus DNA | |
JP2001504468A (ja) | L―β―ジオキソランウリジン類似体及びウイルス感染の治療とその予防方法 | |
Nagahata et al. | Effect of oxetanocin G, a novel nucleoside analog, on DNA synthesis by hepatitis B virus virions | |
Meisel et al. | Inhibition of hepatitis B virus DNA polymerase by 3′‐fluorothymidine triphosphate and other modified nucleoside triphosphate analogs | |
EP0316592A2 (de) | 3'-Fluor-2',3'-dideoxyuridin und seine therapeutische Verwendung | |
Stening et al. | Antiherpes activity of [E]-5-(1-propenyl)-2′-deoxyuridine and 5-(1-propenyl)-1-β-d-arabinofuranosyluracil | |
Sim et al. | Possible molecular basis for antiviral activity of certain 5-substituted deoxyuridines | |
HU198393B (en) | Process for production of medical composition suitable for treatment of hepatitis containing as active substance derivatives of piramidin-nucleoside | |
EP1727814B1 (de) | Nukleosidanaloga mit antiviraler wirkung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired | ||
EXP | Patent expired |