DE3877658D1 - 4'-deshydroxyepipodophyllotoxinglucoside und ihre verwendung. - Google Patents

4'-deshydroxyepipodophyllotoxinglucoside und ihre verwendung.

Info

Publication number
DE3877658D1
DE3877658D1 DE8888113524T DE3877658T DE3877658D1 DE 3877658 D1 DE3877658 D1 DE 3877658D1 DE 8888113524 T DE8888113524 T DE 8888113524T DE 3877658 T DE3877658 T DE 3877658T DE 3877658 D1 DE3877658 D1 DE 3877658D1
Authority
DE
Germany
Prior art keywords
deshydroxyepipodophyllotoxin
deshydroxyepipodophyllotoxinglucoside
deshydroxyetoposide
glucosides
glucoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888113524T
Other languages
English (en)
Other versions
DE3877658T2 (de
Inventor
Mark G Saulnier
Dolatrai M Vyas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE3877658D1 publication Critical patent/DE3877658D1/de
Application granted granted Critical
Publication of DE3877658T2 publication Critical patent/DE3877658T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8888113524T 1987-08-20 1988-08-19 4'-deshydroxyepipodophyllotoxinglucoside und ihre verwendung. Expired - Fee Related DE3877658T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/087,355 US4868291A (en) 1987-08-20 1987-08-20 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use

Publications (2)

Publication Number Publication Date
DE3877658D1 true DE3877658D1 (de) 1993-03-04
DE3877658T2 DE3877658T2 (de) 1993-05-27

Family

ID=22204690

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888113524T Expired - Fee Related DE3877658T2 (de) 1987-08-20 1988-08-19 4'-deshydroxyepipodophyllotoxinglucoside und ihre verwendung.

Country Status (16)

Country Link
US (1) US4868291A (de)
EP (1) EP0304086B1 (de)
JP (1) JPS6468394A (de)
KR (1) KR900006235B1 (de)
AT (1) ATE84792T1 (de)
AU (1) AU622869B2 (de)
CA (1) CA1317290C (de)
DE (1) DE3877658T2 (de)
DK (1) DK467288A (de)
FI (1) FI88167C (de)
GR (1) GR3006943T3 (de)
IL (1) IL87475A (de)
NO (1) NO167206C (de)
NZ (1) NZ225728A (de)
PT (1) PT88312B (de)
ZA (1) ZA884070B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
IT1243340B (it) * 1990-07-13 1994-06-10 Crinos Industria Farmaco Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
KR100442558B1 (ko) * 1999-05-31 2004-07-30 박경한 손톱깎이가 형성된 포켓툴
AR027687A1 (es) * 2000-03-22 2003-04-09 Yakult Honsha Kk Procedimiento para preparar camptotecina
KR100434033B1 (ko) * 2000-12-01 2004-06-04 박경한 손톱깎이

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US608815A (en) * 1898-08-09 Wagon-pole coupling
GB823068A (en) * 1955-05-13 1959-11-04 Sandoz Ltd Condensation products from glucosides
NL6613143A (de) * 1965-09-21 1967-03-22
CH464957A (de) * 1965-12-14 1968-11-15 Sandoz Ag Verfahren zur Herstellung eines neuen Glucosids
DE3374317D1 (en) * 1982-11-26 1987-12-10 Nippon Kayaku Kk Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフィロトキシン誘導体
JPS60246393A (ja) * 1984-05-22 1985-12-06 Nippon Kayaku Co Ltd エトポシドの新規製造法
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフイロトキシン誘導体
ZA886810B (en) * 1987-12-18 1989-08-30 Bristol Myers Co Epipodophyllotoxin glucoside 4'-acyl derivatives

Also Published As

Publication number Publication date
FI88167B (fi) 1992-12-31
US4868291A (en) 1989-09-19
NO167206C (no) 1991-10-16
FI88167C (fi) 1993-04-13
IL87475A0 (en) 1989-01-31
NO883703D0 (no) 1988-08-19
KR900006235B1 (ko) 1990-08-27
PT88312B (pt) 1995-03-31
KR890003792A (ko) 1989-04-18
AU2119688A (en) 1989-02-23
NO167206B (no) 1991-07-08
CA1317290C (en) 1993-05-04
GR3006943T3 (de) 1993-06-30
FI883812A (fi) 1989-02-21
IL87475A (en) 1992-12-01
EP0304086B1 (de) 1993-01-20
DK467288D0 (da) 1988-08-19
AU622869B2 (en) 1992-04-30
ATE84792T1 (de) 1993-02-15
FI883812A0 (fi) 1988-08-17
DK467288A (da) 1989-02-21
EP0304086A3 (en) 1990-09-05
ZA884070B (en) 1989-04-26
NO883703L (no) 1989-02-21
JPS6468394A (en) 1989-03-14
NZ225728A (en) 1991-06-25
PT88312A (pt) 1989-06-30
EP0304086A2 (de) 1989-02-22
DE3877658T2 (de) 1993-05-27

Similar Documents

Publication Publication Date Title
NO905608D0 (no) Fremgangsmaate for fremstilling av a-nor-steroid-3-karboksylsyrederivater.
ZA889659B (en) Synthesis of 1,2-dioxetanes and intermediates therefor
DE3877658D1 (de) 4'-deshydroxyepipodophyllotoxinglucoside und ihre verwendung.
HU911893D0 (en) Process for producing derivatives of 'radicicol'
GR1000156B (el) ΜΕΘΟΔΟΣ ΠΑΡΑΣΚΕΥΗΣ ΝΕΩΝ ΠΑΡΑΓΩΓΩΝ ΤΡΙΚΥΚΛΙΚΩΝ ΑΜΙΝΩΝ ΤΗΣ ΤΕΤΡΑΥΔΡΟ-5,6,7,8ΝΑΦΘΟ[2,3b] ΔΙΥΔΡΟ-2,3 ΦΟΥΡΑΝΗΣ & ΤΗΣ ΤΕΤΡΑΥΔΡΟ-6,7,8,9 5Η-ΒΕΝΖΟΚΥΚΛΟΕΠΤΑ[2,3Β] ΔΙΥΔΡΟ-2,3 ΦΟΥΡΑΝΗΣ.
ES2062389T3 (es) Acidos glutaramicos sustituidos y sus derivados.
AP8800109A0 (en) "Heterocyclic insecticides".
FR2632952B1 (fr) Procede de preparation d'isocyanates d'arylsulfonyle et des derives d'addition en resultant
EP0310260A3 (de) Platin-Komplex und dessen Verwendung als Anti-Tumor-Agenzien
ES8605460A1 (es) Procedimiento para la obtencion de hidrocarburos percloro- fluorados
DE3788473D1 (de) Züchtung von Keratinozyten-Megakolonien und ihre Verwendung für Bestimmungen.
FR2580636B1 (fr) Nouveaux derives acryliques de l'uree
FR2568707B1 (fr) Panneau d'affichage amovible
AU8003387A (en) Acylation products of bis(2-imidazolin-2-ylhydrazones) of 9,10-anthracenedicarboxaldehyde
ATE66671T1 (de) Gamma-l-glutanyl-4-nitoanilid-derivate und verfahren zur bestimmung von gamma-gtp-aktivitaet unter verwendung dieser derivate.
ES2053474T3 (es) 1,2,3-tiadazol-4-tiolatos substituidos.
IT1227695B (it) Procedimento per la reversione della tossicita' della bromovinildesossiuridina (bvudr)
RO89070A2 (ro) Soi de cartofi "muresan"
IT1211361B (it) Pressa continua per la rifinizione di pellami e simili substrati fibrosi e procedimenti di rifinizione utilizzanti tale pressa
SU1417444A1 (ru) 2,4-Дифенил-3(4-ацетокси-4-метилгексин-2-ил)-3-азабицикло [3,3,1]нонан-9-он, проявляющий противовоспалительную активность
IT1204957B (it) Miscela per il consolidamento e/o la concimazione di terreni
CS376487A1 (en) Connection of nmr-spectrometer' linear exciting channel

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee