DE3876607T2 - Optisch getrennte derivate von neuroprotektivem aminopyrrolidin. - Google Patents
Optisch getrennte derivate von neuroprotektivem aminopyrrolidin.Info
- Publication number
- DE3876607T2 DE3876607T2 DE8888202602T DE3876607T DE3876607T2 DE 3876607 T2 DE3876607 T2 DE 3876607T2 DE 8888202602 T DE8888202602 T DE 8888202602T DE 3876607 T DE3876607 T DE 3876607T DE 3876607 T2 DE3876607 T2 DE 3876607T2
- Authority
- DE
- Germany
- Prior art keywords
- aminopyrrolidine
- neuroprotective
- optically separate
- derivatives
- separate derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000324 neuroprotective effect Effects 0.000 title 1
- SBMSLRMNBSMKQC-UHFFFAOYSA-N pyrrolidin-1-amine Chemical compound NN1CCCC1 SBMSLRMNBSMKQC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
- C07C323/47—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878727792A GB8727792D0 (en) | 1987-11-27 | 1987-11-27 | Therapeutic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3876607D1 DE3876607D1 (de) | 1993-01-21 |
DE3876607T2 true DE3876607T2 (de) | 1993-05-13 |
Family
ID=10627624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888202602T Expired - Fee Related DE3876607T2 (de) | 1987-11-27 | 1988-11-18 | Optisch getrennte derivate von neuroprotektivem aminopyrrolidin. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4863953A (de) |
EP (1) | EP0318091B1 (de) |
JP (1) | JP2650739B2 (de) |
CA (1) | CA1329617C (de) |
DE (1) | DE3876607T2 (de) |
GB (1) | GB8727792D0 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8823605D0 (en) * | 1988-10-07 | 1988-11-16 | Merck Sharp & Dohme | Therapeutic agents |
US5145866A (en) * | 1991-04-22 | 1992-09-08 | Hoechst-Roussel Pharmaceuticals Incorporated | Method of treating anxiety with the aid of r(+)-3-amino-1-hydroxy-pyrrolidin-2-one |
GB9109007D0 (en) * | 1991-04-26 | 1991-06-12 | Merck Sharp & Dohme | Therapeutic method |
US5153193A (en) * | 1991-10-01 | 1992-10-06 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs |
US6025355A (en) * | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
US6756389B2 (en) | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
WO2010014943A2 (en) * | 2008-08-01 | 2010-02-04 | Bioxiness Pharmaceutics, Inc. | Methionine analogs and methods of using same |
EP3427729A1 (de) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH157426A (de) * | 1931-03-26 | 1932-09-30 | Baumann Carl | Ovales Rohr für Gefrierplatten künstlicher Eisbahnen. |
GB1041861A (en) * | 1962-03-14 | 1966-09-07 | Organon Labor Ltd | Pyrrolidone derivatives and pharmaceutical preparations containing them |
-
1987
- 1987-11-27 GB GB878727792A patent/GB8727792D0/en active Pending
-
1988
- 1988-11-18 US US07/273,392 patent/US4863953A/en not_active Expired - Fee Related
- 1988-11-18 EP EP88202602A patent/EP0318091B1/de not_active Expired - Lifetime
- 1988-11-18 DE DE8888202602T patent/DE3876607T2/de not_active Expired - Fee Related
- 1988-11-22 CA CA000583723A patent/CA1329617C/en not_active Expired - Fee Related
- 1988-11-28 JP JP63298421A patent/JP2650739B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA1329617C (en) | 1994-05-17 |
EP0318091A3 (en) | 1989-08-30 |
JPH01186866A (ja) | 1989-07-26 |
DE3876607D1 (de) | 1993-01-21 |
GB8727792D0 (en) | 1987-12-31 |
US4863953A (en) | 1989-09-05 |
EP0318091A2 (de) | 1989-05-31 |
JP2650739B2 (ja) | 1997-09-03 |
EP0318091B1 (de) | 1992-12-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |