DE3863876D1 - Perfluorkronenaether fuer die magnetische resonanzdarstellung mit fluor. - Google Patents

Perfluorkronenaether fuer die magnetische resonanzdarstellung mit fluor.

Info

Publication number
DE3863876D1
DE3863876D1 DE8888114952T DE3863876T DE3863876D1 DE 3863876 D1 DE3863876 D1 DE 3863876D1 DE 8888114952 T DE8888114952 T DE 8888114952T DE 3863876 T DE3863876 T DE 3863876T DE 3863876 D1 DE3863876 D1 DE 3863876D1
Authority
DE
Germany
Prior art keywords
perfluorkronenaether
fluor
magnetic resonance
resonance display
display
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888114952T
Other languages
English (en)
Inventor
Frank Kenneth Schweighardt
Joseph A Rubertone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Air Products and Chemicals Inc
Original Assignee
Air Products and Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Air Products and Chemicals Inc filed Critical Air Products and Chemicals Inc
Application granted granted Critical
Publication of DE3863876D1 publication Critical patent/DE3863876D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
DE8888114952T 1987-09-18 1988-09-13 Perfluorkronenaether fuer die magnetische resonanzdarstellung mit fluor. Expired - Lifetime DE3863876D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/099,442 US4838274A (en) 1987-09-18 1987-09-18 Perfluoro-crown ethers in fluorine magnetic resonance imaging

Publications (1)

Publication Number Publication Date
DE3863876D1 true DE3863876D1 (de) 1991-08-29

Family

ID=22275028

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888114952T Expired - Lifetime DE3863876D1 (de) 1987-09-18 1988-09-13 Perfluorkronenaether fuer die magnetische resonanzdarstellung mit fluor.

Country Status (9)

Country Link
US (1) US4838274A (de)
EP (1) EP0307863B1 (de)
JP (1) JPH0621081B2 (de)
KR (1) KR900005730B1 (de)
BR (1) BR8804768A (de)
CA (1) CA1328069C (de)
DE (1) DE3863876D1 (de)
ES (1) ES2023992B3 (de)
ZA (1) ZA886934B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236694A (en) * 1990-02-21 1993-08-17 The Board Of Regents, The University Of Texas System 19f labelled dextrans and antibodies as nmr imaging and spectroscopy agents
DK0526503T3 (da) * 1990-04-10 1997-10-27 Imarx Pharmaceutical Corp Polymerer som kontrastmedier til magnetisk resonansimagografi
US5368840A (en) * 1990-04-10 1994-11-29 Imarx Pharmaceutical Corp. Natural polymers as contrast media for magnetic resonance imaging
US5196348A (en) * 1990-06-11 1993-03-23 Air Products And Chemicals, Inc. Perfluoro-crown ethers in fluorine magnetic resonance spectroscopy of biopsied tissue
US5068098A (en) * 1990-06-11 1991-11-26 Air Products And Chemicals, Inc. Perfluoro-crown ethers in fluorine magnetic resonance spectroscopy
US5146014A (en) * 1991-07-02 1992-09-08 Air Products And Chemicals, Inc. Perfluoroethyldimethyl cyclohexane
US5318770A (en) * 1991-10-25 1994-06-07 Mallinckrodt Medical, Inc. Trifluoromethyl analogs of X-ray contrast media for magnetic resonance imaging
GB9301898D0 (en) * 1993-01-30 1993-03-17 Univ Liverpool Method for localising and measuring the profileration of cancer and compositions for same
US5362478A (en) * 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US5504327A (en) * 1993-11-04 1996-04-02 Hv Ops, Inc. (H-Nu) Electrospray ionization source and method for mass spectrometric analysis
US7047171B1 (en) 1995-12-08 2006-05-16 Sproch Norman K Method for the characterization of the three-dimensional structure of proteins employing mass spectrometric analysis and computational feedback modeling
US20060277017A1 (en) * 1993-11-04 2006-12-07 Sproch Norman K Method for the characterization of the three-dimensional structure of proteins employing mass spectrometric analysis and computational feedback modeling
US5660815A (en) * 1995-04-28 1997-08-26 Molecular Biosystems, Inc. Water soluble fluorinated fatty acid sulfonate derivatives useful as magnetic resonance imaging agents
US5861175A (en) * 1996-03-15 1999-01-19 Alliance Pharmaceutical Corp. Use of fluorocarbons for diagnosis and treatment of articular disorders
US6574497B1 (en) 2000-12-22 2003-06-03 Advanced Cardiovascular Systems, Inc. MRI medical device markers utilizing fluorine-19
AU2005209169B2 (en) 2004-01-16 2010-12-16 Carnegie Mellon University Cellular labeling for nuclear magnetic resonance techniques
US20060183800A1 (en) * 2004-11-12 2006-08-17 Xianqi Kong Methods and fluorinated compositions for treating amyloid-related diseases
EP2010646A2 (de) 2006-04-14 2009-01-07 Carnegie Mellon University Zellbeschriftung und -quantifizierung für nukleare magnetresonanzverfahren
JP2009533061A (ja) * 2006-04-14 2009-09-17 セルセンス， インコーポレイテッド 細胞の標識を評価する方法
DE102006049821A1 (de) 2006-10-18 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung
US8498688B2 (en) * 2007-03-19 2013-07-30 Koninklijke Philips N.V. Magnetic resonance device and method
CA2693678C (en) * 2007-07-10 2017-02-14 Carnegie Mellon University Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques
AU2009241762B2 (en) * 2008-05-02 2015-07-16 Celsense Inc. Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
EP3442595A1 (de) 2016-04-14 2019-02-20 Polytherics Limited Konjugate und konjugationsreagenzien mit einem linker, mit mindestens zwei (-ch2-ch2-0-) einheiten in einem ring

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4523039A (en) * 1980-04-11 1985-06-11 The University Of Texas Method for forming perfluorocarbon ethers
FI64282C (fi) * 1981-06-04 1983-11-10 Instrumentarium Oy Diagnosapparatur foer bestaemmande av vaevnadernas struktur oc sammansaettning
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
AT392004B (de) * 1981-10-27 1991-01-10 Hybritech Inc Verfahren zur herstellung eines monoklonalen antikoerpers gegen tumor-assoziiertes antigen und dessen verwendung
US4467351A (en) * 1981-11-30 1984-08-21 Yen Wang Minimal radiologic imaging method and apparatus
FI65365C (fi) * 1982-07-07 1984-05-10 Instrumentarium Oy Spolanordning
FI65862C (fi) * 1982-10-11 1984-07-10 Instrumentarium Oy Nmr-avbildningsapparat
US4577636A (en) * 1982-11-23 1986-03-25 The Beth Israel Hospital Association Method for diagnosis of atherosclerosis
EP0112582B1 (de) * 1982-12-27 1987-03-18 Kabushiki Kaisha Toshiba Sichtgerät für Überlagerungsbilder
US4503844A (en) * 1983-01-13 1985-03-12 Fischer Imaging Corporation Surgical table
US4586511A (en) * 1983-03-04 1986-05-06 Children's Hospital Medical Center Methods and compositions for detecting and imaging a gas in an animal by nuclear magnetic resonance
US4558279A (en) * 1983-03-07 1985-12-10 University Of Cincinnati Methods for detecting and imaging a temperature of an object by nuclear magnetic resonance
US4544545A (en) * 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
JPS6080747A (ja) * 1983-10-11 1985-05-08 Utsunomiyadaigakuchiyou 非線形磁場勾配を用いた核磁気共鳴映像化方法
US4573014A (en) * 1983-11-09 1986-02-25 Duke University NMR Imaging method and apparatus
US4570004A (en) * 1984-04-06 1986-02-11 The Board Of Regents, University Of Texas System Perfluoro crown ethers
US4652643A (en) * 1984-07-31 1987-03-24 The Hilton-Davis Chemical Company 3-amido-7-disubstituted amino-10-carbonylphenothiazines
US4561001A (en) * 1984-07-31 1985-12-24 The Hilton-Davis Chemical Co. Electrochromic marking systems
US4612185A (en) * 1984-10-15 1986-09-16 Mallinckrodt, Inc. Methods and compositions for enhancing magnetic resonance imaging
US4639364A (en) * 1984-11-14 1987-01-27 Mallinckrodt, Inc. Methods and compositions for enhancing magnetic resonance imaging
US4604743A (en) * 1984-11-21 1986-08-05 North American Philips Corporation Bus structure for an image processor
US4654593A (en) * 1985-02-13 1987-03-31 University Of Cincinnati Method for chemical and tomographic analysis of a moving object by nuclear magnetic resonance
US4631495A (en) * 1985-05-06 1986-12-23 General Electric Company Low-noise RF preamplifier (especially for nuclear magnetic resonance system)

Also Published As

Publication number Publication date
BR8804768A (pt) 1989-04-25
KR890004669A (ko) 1989-05-09
EP0307863A1 (de) 1989-03-22
JPH0621081B2 (ja) 1994-03-23
US4838274A (en) 1989-06-13
ZA886934B (en) 1990-05-30
JPH01107751A (ja) 1989-04-25
ES2023992B3 (es) 1992-02-16
KR900005730B1 (ko) 1990-08-09
EP0307863B1 (de) 1991-07-24
CA1328069C (en) 1994-03-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee