KR890004669A - 불소 자기 공명 이미징용의 퍼플루오로-크라운 에테르 - Google Patents

불소 자기 공명 이미징용의 퍼플루오로-크라운 에테르 Download PDF

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KR890004669A
KR890004669A KR1019880012063A KR880012063A KR890004669A KR 890004669 A KR890004669 A KR 890004669A KR 1019880012063 A KR1019880012063 A KR 1019880012063A KR 880012063 A KR880012063 A KR 880012063A KR 890004669 A KR890004669 A KR 890004669A
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fluorine
perfluoro
direct injection
magnetic resonance
cavity
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KR1019880012063A
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KR900005730B1 (ko
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케네트 슈웨이하르드트 프랭크
에이·루베르톤 조셉
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윌리암 에프·마쉬
에어 프로덕츠 앤드 케미칼스 인코오포 레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

내용 없음

Description

불소 자기 공명 이미징용의 퍼플루오로-크라운 에테르
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 신체 조직 및 기관의 불소 자기 공명 이미지를 제공하여 그 조직 및 기관을 이미지화 하기에 충분한 양으로 불소-함유 시약을 포유류에 투여함으로써 신체 조직 및 불소 자기 공명 이미지을 산출하는 방법에 있어서, 불소-함유 시약으로서 퍼플루오로 15-크라운-5 에테르를 사용하는 것을 특징을 하는 불소 자기 공명 이미지의 산출 방법.
  2. 제1항에 있어서, 상기 퍼플루오로 15-크라운-5 에테르는 수용성의 등장 유탁액 형태로 투여되는 것을 특징으로 하는 방법.
  3. 제2항에 있어서, 유탁액에서 퍼플루오로 15-크라운-5에테르의 농도는 5 내지 25중량%인 것을 특정으로 하는 방법.
  4. 제1항에 있어서, 상기 불소-함유 시약은 동물의 뇌척수액에 투여되는 것을 특징으로 하는 방법.
  5. 제1항에 있어서, 불소-함유 시약은 신체 부위로의 직접 주사 신체 공동(흉곽 공동, 복막)으로의 직접 주사, 체액실(CSF)으로서의 직접주사, 공극(지망막강)으로의 직접주사, 관절낭으로의 직접주사, 혈류로의 직접주사 또는 인할레이숀으로 구성되는 그룹으로부터 선택되는 방법에 의해 투여되는 것을 특징으로 하는 방법.
  6. 제1항에 있어서, 포유류에게 상기 불소 함유시약을 투여한 후, 바라는 바의 조직을 생검하고, 생검 및 추출된 조직을 이미지화하는 것을 특징으로 하는 방법.
  7. 제1항에 있어서, 이미징은 척수조 그래프인 것을 특징으로 하는 방법.
  8. 제1항에 있어서, 이미징은 뇌조 그래프인 것을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880012063A 1987-09-18 1988-09-16 불소 자기 공명 이미징용의 퍼플루오로-크라운 에테르 KR900005730B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US099.442 1987-09-18
US07/099,442 US4838274A (en) 1987-09-18 1987-09-18 Perfluoro-crown ethers in fluorine magnetic resonance imaging

Publications (2)

Publication Number Publication Date
KR890004669A true KR890004669A (ko) 1989-05-09
KR900005730B1 KR900005730B1 (ko) 1990-08-09

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KR1019880012063A KR900005730B1 (ko) 1987-09-18 1988-09-16 불소 자기 공명 이미징용의 퍼플루오로-크라운 에테르

Country Status (9)

Country Link
US (1) US4838274A (ko)
EP (1) EP0307863B1 (ko)
JP (1) JPH0621081B2 (ko)
KR (1) KR900005730B1 (ko)
BR (1) BR8804768A (ko)
CA (1) CA1328069C (ko)
DE (1) DE3863876D1 (ko)
ES (1) ES2023992B3 (ko)
ZA (1) ZA886934B (ko)

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Also Published As

Publication number Publication date
BR8804768A (pt) 1989-04-25
EP0307863A1 (en) 1989-03-22
JPH0621081B2 (ja) 1994-03-23
DE3863876D1 (de) 1991-08-29
US4838274A (en) 1989-06-13
ZA886934B (en) 1990-05-30
JPH01107751A (ja) 1989-04-25
ES2023992B3 (es) 1992-02-16
KR900005730B1 (ko) 1990-08-09
EP0307863B1 (en) 1991-07-24
CA1328069C (en) 1994-03-29

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