DE3853608T2 - Zyklische Anthranil-carbonsäurederivate und Verfahren zu deren Herstellung. - Google Patents

Zyklische Anthranil-carbonsäurederivate und Verfahren zu deren Herstellung.

Info

Publication number
DE3853608T2
DE3853608T2 DE3853608T DE3853608T DE3853608T2 DE 3853608 T2 DE3853608 T2 DE 3853608T2 DE 3853608 T DE3853608 T DE 3853608T DE 3853608 T DE3853608 T DE 3853608T DE 3853608 T2 DE3853608 T2 DE 3853608T2
Authority
DE
Germany
Prior art keywords
anthranil
cyclic
preparation
carboxylic acid
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3853608T
Other languages
English (en)
Other versions
DE3853608D1 (de
Inventor
Eisuke Kojima
Shizuyoshi Fujimori
Katsuya Awano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63236295A external-priority patent/JPH01279867A/ja
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3853608D1 publication Critical patent/DE3853608D1/de
Publication of DE3853608T2 publication Critical patent/DE3853608T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE3853608T 1987-10-02 1988-09-29 Zyklische Anthranil-carbonsäurederivate und Verfahren zu deren Herstellung. Expired - Fee Related DE3853608T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24960887 1987-10-02
JP879388 1988-01-19
JP63236295A JPH01279867A (ja) 1987-10-02 1988-09-22 新規環状アントラニル酸誘導体及びその製造法

Publications (2)

Publication Number Publication Date
DE3853608D1 DE3853608D1 (de) 1995-05-24
DE3853608T2 true DE3853608T2 (de) 1996-01-04

Family

ID=27278180

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853608T Expired - Fee Related DE3853608T2 (de) 1987-10-02 1988-09-29 Zyklische Anthranil-carbonsäurederivate und Verfahren zu deren Herstellung.

Country Status (8)

Country Link
US (3) US4956372A (de)
EP (1) EP0310096B1 (de)
KR (1) KR960010350B1 (de)
CN (1) CN1032788A (de)
CA (1) CA1317294C (de)
DE (1) DE3853608T2 (de)
ES (1) ES2073396T3 (de)
HU (1) HU204802B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124325A (en) * 1989-06-13 1992-06-23 Kyorin Pharmaceutical Co., Ltd. Therapeutic agents of metabolic bone disease
JPH0317061A (ja) * 1989-06-13 1991-01-25 Kyorin Pharmaceut Co Ltd 新規環状アントラニル酸酢酸誘導体
US5112836A (en) * 1989-06-19 1992-05-12 Kyorin Pharmaceutical Co., Ltd. Cyclic anthranililc acid carboxylic acid derivatives and medical therapeutic use thereof
JPH0327357A (ja) * 1989-06-26 1991-02-05 Kyorin Pharmaceut Co Ltd 新規環状アントラニル酸誘導体及びその製造法
US5248777A (en) * 1989-09-19 1993-09-28 Allergan, Inc. Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
JP3209568B2 (ja) * 1991-04-16 2001-09-17 杏林製薬株式会社 新規環状アミノフェニル酢酸誘導体、その製造法及びそれらを有効成分とする免疫応答の修飾剤
FR2714381B1 (fr) * 1993-12-29 1996-02-02 Pharmascience Lab Dérivés de la benzoxazine, leurs procédés d'obtention et leur utilisation en tant que médicaments .
US5696127A (en) 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US6696459B1 (en) 1994-12-22 2004-02-24 Ligand Pharmaceuticals Inc. Steroid receptor modulator compounds and methods
US6063806A (en) * 1995-10-05 2000-05-16 Kyoto Pharmaceutical Industries, Ltd. Indolyl or indolinyl derivatives and medicinal use thereof as ACAT or lipid peroxidation inhibitors
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
GB9724586D0 (en) * 1997-11-20 1998-01-21 Rhone Poulenc Agriculture New herbicides
FR2779144B1 (fr) * 1998-05-29 2000-06-30 Adir Nouveaux composes 8-amino-1,4-benzoxaziniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1999067238A2 (en) 1998-06-25 1999-12-29 Sepracor, Inc. Tetrahydroquinoline-indole derivatives antimicrobial agents, their uses and compositions containing them
WO2004007450A1 (ja) * 2002-07-17 2004-01-22 Kyoto Pharmaceutical Industries, Ltd. 新規インドリン化合物およびその医薬用途
DE602007012910D1 (de) 2006-08-15 2011-04-14 Actelion Pharmaceuticals Ltd Azetidinverbindungen als orexin-rezeptor-antagonisten
WO2013076590A1 (en) * 2011-11-23 2013-05-30 Oxygen Healthcare Research Pvt. Ltd Benzothiazine compounds as h3 receptor ligands

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2733371A (en) * 1970-04-14 1972-10-12 A. H. Robins Company, Incorporated 5, 7-DISUBSTITUTED-l, 9-ALKYLENE-l, 4-BENZODIAZEPIN-2 ONES
US4843082A (en) * 1986-05-05 1989-06-27 E. R. Squibb & Sons, Inc. 1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic use thereof

Also Published As

Publication number Publication date
CA1317294C (en) 1993-05-04
US4956372A (en) 1990-09-11
EP0310096A3 (en) 1990-10-31
CN1032788A (zh) 1989-05-10
US5281600A (en) 1994-01-25
HU204802B (en) 1992-02-28
EP0310096A2 (de) 1989-04-05
DE3853608D1 (de) 1995-05-24
ES2073396T3 (es) 1995-08-16
KR890006604A (ko) 1989-06-14
HUT50459A (en) 1990-02-28
US5147874A (en) 1992-09-15
EP0310096B1 (de) 1995-04-19
KR960010350B1 (ko) 1996-07-30

Similar Documents

Publication Publication Date Title
DE3786781T2 (de) 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäure-Derivate und Verfahren zu deren Herstellung.
DE58909834D1 (de) Phthalimidoperoxihexansäure, Verfahren zu deren Herstellung und deren Verwendung
DE3650018T2 (de) Chinolin-Derivate und Verfahren zu deren Herstellung.
ATE113585T1 (de) Aminsäure-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
DE3852738T2 (de) Thermoplastische Zusammensetzung und Verfahren zu deren Herstellung.
DE3853608T2 (de) Zyklische Anthranil-carbonsäurederivate und Verfahren zu deren Herstellung.
DE69029186D1 (de) 3-Indolbrenztraubensäure, Verfahren zu deren Herstellung und deren therapeutische Verwendung
DE3888217T2 (de) Supraleitende Zusammensetzungen und Verfahren zu deren Herstellung.
DE59007528D1 (de) Biskationische säureamid- und -imidderivate und verfahren zu ihrer herstellung.
DE3770982D1 (de) Diphosphonsaeure-verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel.
DE3862937D1 (de) 3-oxo-propannitril heteroarylderivate und verfahren zu deren herstellung.
ATA87388A (de) Neue purinylribofuranuronsaeurederivate, verfahren zu deren herstellung und sie enthaltende therapeutische praeparate
DE68920063T2 (de) Derivate von Benzoesäure und Verfahren zu deren Herstellung.
ATA328587A (de) Neue furanuronsaeure-derivate, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
DE3481512D1 (de) Aroylbenzofuran- und aroylbenzothiophenessigsaeuren und -propionsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DE3751866D1 (de) Polyimidfolie und Verfahren zu deren Herstellung
ATA272382A (de) Verfahren zur herstellung von neuen 3,7-diazabicyclo/3,3,1/ nonanderivaten, deren stereoisomren und physiologisch vertraeglichen saeureadditionssalzen
DE3887283D1 (de) Kondensierte Acetessigsäureester-Titanchelate und Verfahren zu deren Herstellung.
DE3672931D1 (de) Chinoloncarbonsaeurederivate und verfahren zu ihrer herstellung.
DE3785032T2 (de) Carbonsäuregemisch und Verfahren zu seiner Herstellung.
DE3763407D1 (de) Schwefelsaeureester-gruppen enthaltende naphthalimide, verfahren zu deren herstellung und deren verwendung.
DE3860496D1 (de) Cyanoguanidinderivate und verfahren zu deren herstellung.
DE3867392D1 (de) Phenoxyalkancarbonsaeurederivate und verfahren zu ihrer herstellung.
DE3880904T2 (de) Weinsäureamidderivate und Verfahren zu ihrer Herstellung.
DE59005327D1 (de) Substituierte Tetrachalkogenfulvalene und Verfahren zu deren Herstellung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee