DE3853191D1 - Arzneimittelträger. - Google Patents

Arzneimittelträger.

Info

Publication number
DE3853191D1
DE3853191D1 DE3853191T DE3853191T DE3853191D1 DE 3853191 D1 DE3853191 D1 DE 3853191D1 DE 3853191 T DE3853191 T DE 3853191T DE 3853191 T DE3853191 T DE 3853191T DE 3853191 D1 DE3853191 D1 DE 3853191D1
Authority
DE
Germany
Prior art keywords
drug carrier
drug
carrier
less
particle diameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3853191T
Other languages
English (en)
Other versions
DE3853191T2 (de
Inventor
Makoto Sugiyama
Atsuhiko Okita
Junzo Seki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of DE3853191D1 publication Critical patent/DE3853191D1/de
Publication of DE3853191T2 publication Critical patent/DE3853191T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Lubricants (AREA)
  • Indole Compounds (AREA)
DE3853191T 1987-10-28 1988-10-28 Arzneimittelträger. Expired - Fee Related DE3853191T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27277087 1987-10-28

Publications (2)

Publication Number Publication Date
DE3853191D1 true DE3853191D1 (de) 1995-04-06
DE3853191T2 DE3853191T2 (de) 1995-10-19

Family

ID=17518498

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853191T Expired - Fee Related DE3853191T2 (de) 1987-10-28 1988-10-28 Arzneimittelträger.

Country Status (15)

Country Link
EP (1) EP0315079B1 (de)
KR (1) KR960013281B1 (de)
CN (1) CN1048182C (de)
AT (1) ATE119031T1 (de)
AU (1) AU623342B2 (de)
BE (1) BE1001760A5 (de)
CA (1) CA1333993C (de)
CH (1) CH677605A5 (de)
DE (1) DE3853191T2 (de)
ES (1) ES2012561A6 (de)
FR (1) FR2622442B1 (de)
GB (1) GB2211408B (de)
IL (1) IL88076A (de)
IT (1) IT1224596B (de)
NL (1) NL193340C (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
EP0361928B1 (de) * 1988-09-29 1994-04-27 Shiseido Company Limited Emulgierte Zusammensetzung
JP2785981B2 (ja) * 1989-11-20 1998-08-13 株式会社資生堂 乳化組成物
TW211015B (de) * 1990-01-11 1993-08-11 Nippon Shinyaku Co Ltd
WO1992007552A1 (en) * 1990-11-06 1992-05-14 Nippon Shinyaku Co., Ltd. Lyophilized preparation and production thereof
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
IL101387A (en) * 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas
WO1993023010A1 (en) 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
ES2168271T3 (es) 1992-09-25 2002-06-16 Novartis Ag Composiciones farmaceuticas que contienen ciclosporinas.
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
WO1995022973A1 (en) * 1994-02-25 1995-08-31 Takeda Chemicals Industries, Ltd. Injectable emulsions containing antifungal triazole derivatives
US5851510A (en) * 1994-05-16 1998-12-22 The Board Of Regents Of The University Of Michigan Hepatocyte-selective oil-in-water emulsion
EP0789580B1 (de) 1994-11-03 2002-06-05 Novartis AG Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
JPH10513200A (ja) * 1995-02-06 1998-12-15 ナノシステムズ エルエルシー 可消化オイル又は脂肪酸中の微粒子分散物である化合物の製剤
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
JP3136352B2 (ja) * 1996-01-22 2001-02-19 参天製薬株式会社 角結膜疾患治療剤
CA2258513A1 (en) * 1996-07-02 1998-01-08 Beat Schmid Topical composition comprising a combination of antihistaminic compounds with terpenoid compounds
ES2229473T3 (es) 1997-01-30 2005-04-16 Novartis Ag Composiciones farmaceuticas sin aceite que contienen ciclosporina a.
US6537561B1 (en) 1997-02-27 2003-03-25 Nippon Shinyaku Co., Ltd. Fat emulsion for oral administration
IL121647A (en) * 1997-08-28 2001-07-24 Pharmateam Dev Ltd Pharmaceutical compositions for the treatment of ocular inflammation comprising dexamethasone palmitate
GR20020100012A (el) * 2002-01-16 2003-09-24 Αγγελικη Κουρουνακη Το γουαιαζουλενιο για χρηση στην προληψη ή θεραπεια καθε τυπου υπερχοληστερολαιμιας, υπερλιπιδαιμιας και καθε διαταραχη λιπιδιων, σε ανθρωπους και ζωα
CN1297271C (zh) * 2003-09-30 2007-01-31 昆明紫健生物技术有限公司 草乌甲素脂肪乳输液及其生产方法
CN100386085C (zh) * 2003-12-17 2008-05-07 昆明紫健生物技术有限公司 一种防治肿瘤的脂肪乳输液及生产方法
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
KR101430767B1 (ko) 2005-07-18 2014-08-19 유니버시티 오브 메사츄세츠 로웰 나노에멀젼 조성물 및 이의 제조 및 사용 방법
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
KR20150028308A (ko) 2006-12-01 2015-03-13 안테리오스, 인코퍼레이티드 펩티드 나노입자 및 이의 용도
JP2010528981A (ja) 2006-12-01 2010-08-26 アンテリオス， インコーポレイテッド 両親媒性実体ナノ粒子
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
WO2010079037A2 (de) * 2008-12-18 2010-07-15 Basf Se Wässrige dispersion umfassend pestizidpartikel und amphiphil
DE102010021688A1 (de) * 2010-05-27 2011-12-01 Qineva Gmbh & Co. Kg Verfahren zur Herstellung eines micellaren Wirkstoffkonzentrats
US9603811B2 (en) * 2013-12-11 2017-03-28 Health-Ever Biotech Co., Ltd Pharmaceutical compositions of carotenoid chylomicrons
CN105483076B (zh) 2015-12-23 2019-01-25 中国科学院生物物理研究所 一种脂肪体的制备方法及其应用
WO2018093465A1 (en) 2016-11-21 2018-05-24 Eirion Therapeutics, Inc. Transdermal delivery of large agents
WO2023178519A1 (zh) * 2022-03-22 2023-09-28 乐普（北京）医疗器械股份有限公司 一种药物涂层、药物球囊及药物球囊制备方法与应用
CN115919759A (zh) * 2022-12-27 2023-04-07 沈阳药科大学 一种低聚集体眼用纳米制剂及其制备方法和用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
DE3225848A1 (de) * 1982-07-07 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Kortikoidhaltige zubereitung zur topischen applikation
DE3225706C2 (de) * 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
JPS59193814A (ja) * 1983-04-20 1984-11-02 Ajinomoto Co Inc アミノ酸含有脂肪乳剤
JPS60231609A (ja) * 1984-04-28 1985-11-18 Terumo Corp リポソ−ム製剤
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
CA1298548C (en) * 1984-10-22 1992-04-07 Cary Arnet Presant Method of delivering micellular particles encapsulating imaging and chemotherapeutic agents to tumors in a body
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
JPS6348214A (ja) * 1986-08-18 1988-02-29 Morishita Seiyaku Kk １−〔２−（２，４−ジクロロフエニル）−３−メチル−１−ペンテニル〕−１ｈ−イミダゾ−ルを含有する水中油型脂肪乳剤
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules

Also Published As

Publication number Publication date
IT1224596B (it) 1990-10-04
DE3853191T2 (de) 1995-10-19
GB2211408B (en) 1992-04-15
GB2211408A (en) 1989-07-05
NL8802657A (nl) 1989-05-16
GB8825024D0 (en) 1988-11-30
KR960013281B1 (ko) 1996-10-02
ES2012561A6 (es) 1990-04-01
CA1333993C (en) 1995-01-17
FR2622442A1 (fr) 1989-05-05
CN1042080A (zh) 1990-05-16
CN1048182C (zh) 2000-01-12
IT8848502A0 (it) 1988-10-27
ATE119031T1 (de) 1995-03-15
IL88076A0 (en) 1989-06-30
AU2447288A (en) 1989-05-04
AU623342B2 (en) 1992-05-14
BE1001760A5 (fr) 1990-02-27
EP0315079A1 (de) 1989-05-10
NL193340B (nl) 1999-03-01
CH677605A5 (de) 1991-06-14
NL193340C (nl) 1999-07-02
EP0315079B1 (de) 1995-03-01
FR2622442B1 (fr) 1993-10-22
KR890006225A (ko) 1989-06-12
IL88076A (en) 1993-01-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: HANSMANN & VOGESER, 81369 MUENCHEN

8339 Ceased/non-payment of the annual fee