DE3851865T2 - Verfahren zur Umwandlung des niedrigschmelzenden Polymorphs von Buspirone hydrochlorid in das höherschmelzende. - Google Patents
Verfahren zur Umwandlung des niedrigschmelzenden Polymorphs von Buspirone hydrochlorid in das höherschmelzende.Info
- Publication number
- DE3851865T2 DE3851865T2 DE3851865T DE3851865T DE3851865T2 DE 3851865 T2 DE3851865 T2 DE 3851865T2 DE 3851865 T DE3851865 T DE 3851865T DE 3851865 T DE3851865 T DE 3851865T DE 3851865 T2 DE3851865 T2 DE 3851865T2
- Authority
- DE
- Germany
- Prior art keywords
- melting
- converting
- low
- polymorph
- buspirone hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Glass Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Gears, Cams (AREA)
- Developing Agents For Electrophotography (AREA)
- Arrangement Or Mounting Of Propulsion Units For Vehicles (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Body Structure For Vehicles (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/090,302 US4810789A (en) | 1987-08-28 | 1987-08-28 | Process for buspirone hydrochloride polymorphic crystalline form conversion |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3851865D1 DE3851865D1 (de) | 1994-11-24 |
DE3851865T2 true DE3851865T2 (de) | 1995-02-23 |
Family
ID=22222189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3851865T Expired - Fee Related DE3851865T2 (de) | 1987-08-28 | 1988-08-26 | Verfahren zur Umwandlung des niedrigschmelzenden Polymorphs von Buspirone hydrochlorid in das höherschmelzende. |
Country Status (23)
Country | Link |
---|---|
US (1) | US4810789A (de) |
EP (1) | EP0304940B1 (de) |
JP (1) | JP2702519B2 (de) |
KR (1) | KR970011294B1 (de) |
AT (1) | ATE113044T1 (de) |
AU (1) | AU618746B2 (de) |
CY (1) | CY1839A (de) |
DE (1) | DE3851865T2 (de) |
DK (1) | DK478688A (de) |
ES (1) | ES2060632T3 (de) |
FI (1) | FI91066C (de) |
HK (1) | HK71495A (de) |
HU (1) | HU199831B (de) |
IE (1) | IE65988B1 (de) |
IL (1) | IL87292A (de) |
MY (1) | MY100863A (de) |
NO (1) | NO169284C (de) |
NZ (1) | NZ225895A (de) |
OA (1) | OA08907A (de) |
PT (1) | PT88355B (de) |
SU (1) | SU1731056A3 (de) |
YU (1) | YU46961B (de) |
ZA (1) | ZA885867B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5631017A (en) * | 1993-03-26 | 1997-05-20 | Beth Israel Deaconess Medical Center, Inc. | Topical application of buspirone for treatment of pathological conditions associated with immune responses |
US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
HU217129B (hu) * | 1993-07-16 | 1999-11-29 | EGIS Gyógyszergyár Rt. | Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására |
US5637314A (en) * | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
KR100322018B1 (ko) * | 1999-01-23 | 2002-02-04 | 윤종용 | 음성대역 잡음 보상장치 |
US6465255B1 (en) * | 1999-01-29 | 2002-10-15 | The Regents Of The University Of California | Method for identifying and probing phase transitions in materials |
DE60216641T2 (de) * | 2002-04-19 | 2007-09-27 | Faes Farma S.A. | Polymorph von 4-ä2-ä4-ä1-(2-ethoxyethyl)-1h-benzimidazol-2-ylü-1-piperidinylüethylü-alpha, alpha-dimethylbenzolessigsäure |
JP2010013472A (ja) * | 2009-09-09 | 2010-01-21 | Faes Farma Sa | 4−[2−[1−(2−エトキシエチル)−1H−ベンズイミダゾール−2−イル]−1−ピペリジニル]エチル]−α,α−ジメチルベンゼノ酢酸の多形体 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
US3976776A (en) * | 1972-12-06 | 1976-08-24 | Mead Johnson & Company | Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones |
US4351939A (en) * | 1980-10-16 | 1982-09-28 | Mead Johnson & Company | Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process |
US4476248A (en) * | 1983-02-28 | 1984-10-09 | The Upjohn Company | Crystallization of ibuprofen |
DD263531A5 (de) * | 1986-10-21 | 1989-01-04 | ������@���Kk�� | Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen |
US5015646A (en) * | 1987-08-28 | 1991-05-14 | Bristol-Myers Squibb Co. | Pharmaceutically useful polymorphic modification of buspirone |
-
1987
- 1987-08-28 US US07/090,302 patent/US4810789A/en not_active Expired - Lifetime
-
1988
- 1988-08-01 IL IL87292A patent/IL87292A/xx not_active IP Right Cessation
- 1988-08-02 MY MYPI88000876A patent/MY100863A/en unknown
- 1988-08-02 IE IE236288A patent/IE65988B1/en not_active IP Right Cessation
- 1988-08-05 AU AU20480/88A patent/AU618746B2/en not_active Ceased
- 1988-08-10 ZA ZA885867A patent/ZA885867B/xx unknown
- 1988-08-22 YU YU160488A patent/YU46961B/sh unknown
- 1988-08-22 NZ NZ225895A patent/NZ225895A/en unknown
- 1988-08-25 NO NO883806A patent/NO169284C/no unknown
- 1988-08-26 FI FI883960A patent/FI91066C/fi not_active IP Right Cessation
- 1988-08-26 PT PT88355A patent/PT88355B/pt not_active IP Right Cessation
- 1988-08-26 DK DK478688A patent/DK478688A/da not_active Application Discontinuation
- 1988-08-26 DE DE3851865T patent/DE3851865T2/de not_active Expired - Fee Related
- 1988-08-26 JP JP63212318A patent/JP2702519B2/ja not_active Expired - Fee Related
- 1988-08-26 HU HU884472A patent/HU199831B/hu not_active IP Right Cessation
- 1988-08-26 OA OA59414A patent/OA08907A/xx unknown
- 1988-08-26 ES ES88113969T patent/ES2060632T3/es not_active Expired - Lifetime
- 1988-08-26 SU SU884356323A patent/SU1731056A3/ru active
- 1988-08-26 AT AT88113969T patent/ATE113044T1/de not_active IP Right Cessation
- 1988-08-26 EP EP88113969A patent/EP0304940B1/de not_active Expired - Lifetime
- 1988-08-27 KR KR1019880010968A patent/KR970011294B1/ko not_active IP Right Cessation
-
1995
- 1995-05-11 HK HK71495A patent/HK71495A/xx not_active IP Right Cessation
- 1995-12-01 CY CY183995A patent/CY1839A/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK527888A (da) | Fremgangsmaade til omdannelse af et udgangsmateriale indeholdende fra 1 til 6 carbonatomer per molekyle | |
DK543787D0 (da) | Antibakterielle midler | |
DE3856515D1 (de) | Zwischenprodukte zur Herstellung von benzoheterocyclischen Verbindungen | |
FR2595089B1 (fr) | Procede de purification d'un sel de baryum | |
FI874459A (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten piperidiinijohdannaisten valmistamiseksi | |
DE3851865D1 (de) | Verfahren zur Umwandlung des niedrigschmelzenden Polymorphs von Buspirone hydrochlorid in das höherschmelzende. | |
IT8420358A0 (it) | Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti. | |
FR2570069B1 (fr) | Procede de synthese d'un aluminosilicate cristallin | |
PT86821A (pt) | Process for the preparation of novel tetrazole intermediates useful for the preparation of antihypercholesterolemic compounds | |
FR2575472B1 (fr) | Procede de preparation d'hydrogeno- ou d'halogenosilanes | |
DK0492350T3 (da) | Fremgangsmåde til fremstilling af (S)-vinyl- og (S)-allenyl-GABA | |
ES2042571T3 (es) | N-(s-3-metilftanoil)-d-gamma-glutamil-glicil-d-alanina cristalina, y procedimientos y productos intermedios de la misma. | |
FR2605002B1 (fr) | Procede de synthese d'amines primaires a partir d'esters | |
DE58909745D1 (de) | Tetrahydro-4-phenylimino-3-thiophenessigsäuren | |
DE58909563D1 (de) | 3-Anilino-2-hydroxycarbonyl-4-thiophenessigsäuren | |
RO94124A2 (ro) | Procedeu de obtinere de cristale de spinel magnezian | |
ATE33824T1 (de) | (-)-1-(2-fluorophenyl)-2-tertiobutylamino-1ethanol und seine therapeutische verwendung. | |
MA20825A1 (fr) | Procede de synthese de tetraalkyl-ethenylidenebis phosphonates | |
RO90544A2 (ro) | Procedeu de preparare a esterului izopropilic al acidului 3,4-dihidro-2h-4-hidroxi-1,2-benzotiazin-1,1-dioxi-3-carboxilic | |
RO89953A2 (ro) | Procedeu de obtinere a peroxacizilor alifatici inferiori |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |