DE3781653T2 - Verwendung von cembrane-diterpene verbindungen zur herstellung von zusammensetzungen, die inhibitoren der freigabe von lysosomen enthalten. - Google Patents

Verwendung von cembrane-diterpene verbindungen zur herstellung von zusammensetzungen, die inhibitoren der freigabe von lysosomen enthalten.

Info

Publication number
DE3781653T2
DE3781653T2 DE8787402578T DE3781653T DE3781653T2 DE 3781653 T2 DE3781653 T2 DE 3781653T2 DE 8787402578 T DE8787402578 T DE 8787402578T DE 3781653 T DE3781653 T DE 3781653T DE 3781653 T2 DE3781653 T2 DE 3781653T2
Authority
DE
Germany
Prior art keywords
cembrane
lysosomes
release
compositions containing
producing compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787402578T
Other languages
English (en)
Other versions
DE3781653D1 (de
Inventor
Kohei Umezu
Koichiro Hirayama
Kazuo Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Application granted granted Critical
Publication of DE3781653D1 publication Critical patent/DE3781653D1/de
Publication of DE3781653T2 publication Critical patent/DE3781653T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE8787402578T 1986-12-09 1987-11-16 Verwendung von cembrane-diterpene verbindungen zur herstellung von zusammensetzungen, die inhibitoren der freigabe von lysosomen enthalten. Expired - Fee Related DE3781653T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61292747A JPH0798746B2 (ja) 1986-12-09 1986-12-09 リソゾ−ム放出抑制剤

Publications (2)

Publication Number Publication Date
DE3781653D1 DE3781653D1 (de) 1992-10-15
DE3781653T2 true DE3781653T2 (de) 1993-02-18

Family

ID=17785809

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8787402578T Expired - Fee Related DE3781653T2 (de) 1986-12-09 1987-11-16 Verwendung von cembrane-diterpene verbindungen zur herstellung von zusammensetzungen, die inhibitoren der freigabe von lysosomen enthalten.
DE9191106347T Expired - Fee Related DE3784526T2 (de) 1986-12-09 1987-11-16 Cembran-diterpene-verbindungen zur herstellung von zusammensetzungen, die inhibitoren der histamin-freisetzung enthalten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE9191106347T Expired - Fee Related DE3784526T2 (de) 1986-12-09 1987-11-16 Cembran-diterpene-verbindungen zur herstellung von zusammensetzungen, die inhibitoren der histamin-freisetzung enthalten.

Country Status (4)

Country Link
US (1) US4906794A (de)
EP (2) EP0271387B1 (de)
JP (1) JPH0798746B2 (de)
DE (2) DE3781653T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0454140A (ja) * 1990-06-20 1992-02-21 Mitsubishi Kasei Corp 共役ジエン化合物
US5276217A (en) * 1992-03-19 1994-01-04 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
US6204289B1 (en) 1997-06-05 2001-03-20 Vesna A. Eterovic Cembranoid inhibitors of nicotinic acetylcholine receptors
US6489357B1 (en) 1998-06-04 2002-12-03 University Of Puerto Rico Tobacco cembranoids block the expression of the behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptors
US6300371B1 (en) 1998-11-05 2001-10-09 Indian Institute Of Chemical Technology Rameswaralide and rameswaralide derivatives
EP1351678A2 (de) * 2001-01-02 2003-10-15 Elizabeth Shanahan-Prendergast Behandlung von neoplastischen erkrankungen mit incensol und/oder furanogermacren
AU2003228978A1 (en) * 2002-05-09 2003-11-11 University Of Mississippi Cembranoids with chemopreventive activity
CN105732656B (zh) * 2016-03-31 2017-10-27 中国人民解放军第二军医大学 肉芝软珊瑚中的一种四萜类化合物及其用途
CN109134184B (zh) * 2017-06-16 2021-03-19 中国科学院上海药物研究所 二萜类化合物、其制备方法及用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588365B2 (ja) * 1975-09-22 1983-02-15 キタハラ ヨシオ フホウワ １４ インカンカゴウブツノ セイホウ
JPS5522624A (en) * 1978-08-03 1980-02-18 Mitsubishi Chem Ind Ltd Preparation of diterpene alcohol
JPS5661317A (en) * 1979-10-25 1981-05-26 Mitsubishi Chem Ind Ltd Cembranolide diterpene
JPS61109713A (ja) * 1984-11-05 1986-05-28 Japan Tobacco Inc 抗腫瘍剤
JPH0610177B2 (ja) * 1985-05-08 1994-02-09 エーザイ株式会社 キノン化合物
JPH0794387B2 (ja) * 1986-12-09 1995-10-11 三菱化学株式会社 皮膚用製剤
JPH0794388B2 (ja) * 1987-03-17 1995-10-11 三菱化学株式会社 乾癬治療剤

Also Published As

Publication number Publication date
DE3784526D1 (de) 1993-04-08
EP0271387B1 (de) 1992-09-09
EP0271387A3 (en) 1990-07-25
JPH0798746B2 (ja) 1995-10-25
EP0448128A3 (en) 1991-11-27
EP0448128B1 (de) 1993-03-03
DE3784526T2 (de) 1993-09-09
EP0271387A2 (de) 1988-06-15
EP0448128A2 (de) 1991-09-25
DE3781653D1 (de) 1992-10-15
JPS63145224A (ja) 1988-06-17
US4906794A (en) 1990-03-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee