JPS5661317A - Cembranolide diterpene - Google Patents

Cembranolide diterpene

Info

Publication number
JPS5661317A
JPS5661317A JP13798179A JP13798179A JPS5661317A JP S5661317 A JPS5661317 A JP S5661317A JP 13798179 A JP13798179 A JP 13798179A JP 13798179 A JP13798179 A JP 13798179A JP S5661317 A JPS5661317 A JP S5661317A
Authority
JP
Japan
Prior art keywords
diterpene
give
cembranolide
sarcophytol
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13798179A
Other languages
Japanese (ja)
Other versions
JPS6261007B2 (en
Inventor
Koichiro Hirayama
Junichi Ooya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP13798179A priority Critical patent/JPS5661317A/en
Publication of JPS5661317A publication Critical patent/JPS5661317A/en
Publication of JPS6261007B2 publication Critical patent/JPS6261007B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A new cembranolide diterpene of the formula (R is H, acetyl) (when R is H, the diterpene is named sarcophytol-B and sarcophytol-B diacetate, when R is acetyl).
USE: Antileukemia and intermediate of medicines and agricultural chemicals. As it is susceptible to oxidation by air, cautions should be taken on handling and storage.
PREPARATION: Sarcophyton glaucon living in coral reefs in Indian or Pacific Ocean is dehydrated until it loses the viscous property on the surface, cut into pieces, extracted with methanol or chloroform. The solvent is distilled off to give the crude extract. The crude extract is partitioned to give a lipid fraction, which is subjected to silica-gel column chromatography to give the compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
JP13798179A 1979-10-25 1979-10-25 Cembranolide diterpene Granted JPS5661317A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13798179A JPS5661317A (en) 1979-10-25 1979-10-25 Cembranolide diterpene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13798179A JPS5661317A (en) 1979-10-25 1979-10-25 Cembranolide diterpene

Publications (2)

Publication Number Publication Date
JPS5661317A true JPS5661317A (en) 1981-05-26
JPS6261007B2 JPS6261007B2 (en) 1987-12-18

Family

ID=15211255

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13798179A Granted JPS5661317A (en) 1979-10-25 1979-10-25 Cembranolide diterpene

Country Status (1)

Country Link
JP (1) JPS5661317A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200790A1 (en) * 1984-11-05 1986-11-12 Japan Tobacco Inc. Antineoplastic agent
JPS6317823A (en) * 1986-07-10 1988-01-25 Mitsubishi Chem Ind Ltd Antisolid tumor agent
EP0271387A2 (en) * 1986-12-09 1988-06-15 Mitsubishi Kasei Corporation Cembrane-type diterpene compounds for use in the production of compositions containing lysosome liberation inhibitors
WO1993018651A1 (en) * 1992-03-19 1993-09-30 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04137503U (en) * 1991-06-05 1992-12-22 株式会社三協精機製作所 magnetic head

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200790A1 (en) * 1984-11-05 1986-11-12 Japan Tobacco Inc. Antineoplastic agent
JPS6317823A (en) * 1986-07-10 1988-01-25 Mitsubishi Chem Ind Ltd Antisolid tumor agent
EP0258082A2 (en) * 1986-07-10 1988-03-02 Mitsubishi Kasei Corporation Anti-solid tumor agents
US5300525A (en) * 1986-07-10 1994-04-05 Mitsubishi Kasei Corporation Anti-solid tumor agents
US5387609A (en) * 1986-07-10 1995-02-07 Mitsubishi Kasei Corporation Anti-solid tumor agents
EP0271387A2 (en) * 1986-12-09 1988-06-15 Mitsubishi Kasei Corporation Cembrane-type diterpene compounds for use in the production of compositions containing lysosome liberation inhibitors
EP0448128A2 (en) * 1986-12-09 1991-09-25 Mitsubishi Kasei Corporation Cembrane-type diterpene compounds for use in the production of compositions containing histamine release inhibitors
WO1993018651A1 (en) * 1992-03-19 1993-09-30 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
US5276217A (en) * 1992-03-19 1994-01-04 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
US5349112A (en) * 1992-03-19 1994-09-20 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use

Also Published As

Publication number Publication date
JPS6261007B2 (en) 1987-12-18

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