JPS5661317A - Cembranolide diterpene - Google Patents
Cembranolide diterpeneInfo
- Publication number
- JPS5661317A JPS5661317A JP13798179A JP13798179A JPS5661317A JP S5661317 A JPS5661317 A JP S5661317A JP 13798179 A JP13798179 A JP 13798179A JP 13798179 A JP13798179 A JP 13798179A JP S5661317 A JPS5661317 A JP S5661317A
- Authority
- JP
- Japan
- Prior art keywords
- diterpene
- give
- cembranolide
- sarcophytol
- acetyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A new cembranolide diterpene of the formula (R is H, acetyl) (when R is H, the diterpene is named sarcophytol-B and sarcophytol-B diacetate, when R is acetyl).
USE: Antileukemia and intermediate of medicines and agricultural chemicals. As it is susceptible to oxidation by air, cautions should be taken on handling and storage.
PREPARATION: Sarcophyton glaucon living in coral reefs in Indian or Pacific Ocean is dehydrated until it loses the viscous property on the surface, cut into pieces, extracted with methanol or chloroform. The solvent is distilled off to give the crude extract. The crude extract is partitioned to give a lipid fraction, which is subjected to silica-gel column chromatography to give the compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13798179A JPS5661317A (en) | 1979-10-25 | 1979-10-25 | Cembranolide diterpene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13798179A JPS5661317A (en) | 1979-10-25 | 1979-10-25 | Cembranolide diterpene |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5661317A true JPS5661317A (en) | 1981-05-26 |
JPS6261007B2 JPS6261007B2 (en) | 1987-12-18 |
Family
ID=15211255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13798179A Granted JPS5661317A (en) | 1979-10-25 | 1979-10-25 | Cembranolide diterpene |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5661317A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0200790A1 (en) * | 1984-11-05 | 1986-11-12 | Japan Tobacco Inc. | Antineoplastic agent |
JPS6317823A (en) * | 1986-07-10 | 1988-01-25 | Mitsubishi Chem Ind Ltd | Antisolid tumor agent |
EP0271387A2 (en) * | 1986-12-09 | 1988-06-15 | Mitsubishi Kasei Corporation | Cembrane-type diterpene compounds for use in the production of compositions containing lysosome liberation inhibitors |
WO1993018651A1 (en) * | 1992-03-19 | 1993-09-30 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04137503U (en) * | 1991-06-05 | 1992-12-22 | 株式会社三協精機製作所 | magnetic head |
-
1979
- 1979-10-25 JP JP13798179A patent/JPS5661317A/en active Granted
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0200790A1 (en) * | 1984-11-05 | 1986-11-12 | Japan Tobacco Inc. | Antineoplastic agent |
JPS6317823A (en) * | 1986-07-10 | 1988-01-25 | Mitsubishi Chem Ind Ltd | Antisolid tumor agent |
EP0258082A2 (en) * | 1986-07-10 | 1988-03-02 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
US5300525A (en) * | 1986-07-10 | 1994-04-05 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
US5387609A (en) * | 1986-07-10 | 1995-02-07 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
EP0271387A2 (en) * | 1986-12-09 | 1988-06-15 | Mitsubishi Kasei Corporation | Cembrane-type diterpene compounds for use in the production of compositions containing lysosome liberation inhibitors |
EP0448128A2 (en) * | 1986-12-09 | 1991-09-25 | Mitsubishi Kasei Corporation | Cembrane-type diterpene compounds for use in the production of compositions containing histamine release inhibitors |
WO1993018651A1 (en) * | 1992-03-19 | 1993-09-30 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
US5276217A (en) * | 1992-03-19 | 1994-01-04 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
US5349112A (en) * | 1992-03-19 | 1994-09-20 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
Also Published As
Publication number | Publication date |
---|---|
JPS6261007B2 (en) | 1987-12-18 |
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