JPS5661318A - Cembranolide diterpen - Google Patents

Cembranolide diterpen

Info

Publication number
JPS5661318A
JPS5661318A JP13843079A JP13843079A JPS5661318A JP S5661318 A JPS5661318 A JP S5661318A JP 13843079 A JP13843079 A JP 13843079A JP 13843079 A JP13843079 A JP 13843079A JP S5661318 A JPS5661318 A JP S5661318A
Authority
JP
Japan
Prior art keywords
give
cembranolide
sarcophytol
acetyl
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13843079A
Other languages
Japanese (ja)
Other versions
JPS6320213B2 (en
Inventor
Koichiro Hirayama
Junichi Ooya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP13843079A priority Critical patent/JPS5661318A/en
Publication of JPS5661318A publication Critical patent/JPS5661318A/en
Publication of JPS6320213B2 publication Critical patent/JPS6320213B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:Cembranolide diterperns of the formula (R is H, acetyl), where it is named sarcophytol A, when R is H and sarcophytol A acetate, when acetyl.
USE: Antileukemia and synthetic intermediate of medicines and agricultural chemicals. Caution should be taken on handling and storing, because they are susceptible to oxidation by air.
PREPARATION: Sarcophyton glaucon living in coral reefs in Indian or Pacific Ocean is dehydrated until it loses the viscous property on the surface and extracted with a solvent such as methanol or chloroform. The solvent is distilled off to give the crude extract. The crude extract is partitioned to give a lipid fraction, which is subjected to silica-gel column chromatography to give the compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
JP13843079A 1979-10-26 1979-10-26 Cembranolide diterpen Granted JPS5661318A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13843079A JPS5661318A (en) 1979-10-26 1979-10-26 Cembranolide diterpen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13843079A JPS5661318A (en) 1979-10-26 1979-10-26 Cembranolide diterpen

Publications (2)

Publication Number Publication Date
JPS5661318A true JPS5661318A (en) 1981-05-26
JPS6320213B2 JPS6320213B2 (en) 1988-04-26

Family

ID=15221779

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13843079A Granted JPS5661318A (en) 1979-10-26 1979-10-26 Cembranolide diterpen

Country Status (1)

Country Link
JP (1) JPS5661318A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6317823A (en) * 1986-07-10 1988-01-25 Mitsubishi Chem Ind Ltd Antisolid tumor agent
EP0462616A2 (en) * 1990-06-20 1991-12-27 Mitsubishi Chemical Corporation Conjugated diene compounds, process for producing these compounds and use thereof
WO1993018651A1 (en) * 1992-03-19 1993-09-30 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
CN112876361A (en) * 2021-01-15 2021-06-01 宁波大学 Cedarane diterpenoid compound and preparation method and application thereof
CN113402528A (en) * 2020-03-17 2021-09-17 中国医学科学院药物研究所 Cedarane type macrocyclic diterpenoid compound, preparation method, pharmaceutical composition and application

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL & PHARMACEUTICAL BULLETIN=1979 *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6317823A (en) * 1986-07-10 1988-01-25 Mitsubishi Chem Ind Ltd Antisolid tumor agent
US5300525A (en) * 1986-07-10 1994-04-05 Mitsubishi Kasei Corporation Anti-solid tumor agents
US5387609A (en) * 1986-07-10 1995-02-07 Mitsubishi Kasei Corporation Anti-solid tumor agents
EP0462616A2 (en) * 1990-06-20 1991-12-27 Mitsubishi Chemical Corporation Conjugated diene compounds, process for producing these compounds and use thereof
EP0462616A3 (en) * 1990-06-20 1994-04-20 Mitsubishi Chem Ind
WO1993018651A1 (en) * 1992-03-19 1993-09-30 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
US5276217A (en) * 1992-03-19 1994-01-04 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
US5349112A (en) * 1992-03-19 1994-09-20 University Of Hawaii Cyclic anti-tumor promoter compounds, compositions and methods for production and use
CN113402528A (en) * 2020-03-17 2021-09-17 中国医学科学院药物研究所 Cedarane type macrocyclic diterpenoid compound, preparation method, pharmaceutical composition and application
CN113402528B (en) * 2020-03-17 2023-09-26 中国医学科学院药物研究所 Celastracene type macrocyclic diterpenoid compound, preparation method, pharmaceutical composition and application
CN112876361A (en) * 2021-01-15 2021-06-01 宁波大学 Cedarane diterpenoid compound and preparation method and application thereof
CN112876361B (en) * 2021-01-15 2022-06-14 宁波大学 Cedarane diterpenoid compound and preparation method and application thereof

Also Published As

Publication number Publication date
JPS6320213B2 (en) 1988-04-26

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