DE3765243D1 - Ibuprofen und codein enthaltende, stabile, feste arzneimittel. - Google Patents

Ibuprofen und codein enthaltende, stabile, feste arzneimittel.

Info

Publication number
DE3765243D1
DE3765243D1 DE8787310530T DE3765243T DE3765243D1 DE 3765243 D1 DE3765243 D1 DE 3765243D1 DE 8787310530 T DE8787310530 T DE 8787310530T DE 3765243 T DE3765243 T DE 3765243T DE 3765243 D1 DE3765243 D1 DE 3765243D1
Authority
DE
Germany
Prior art keywords
ibuprofen
codein
stable
medicinal products
solid medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787310530T
Other languages
English (en)
Inventor
Mahendra Govind Pankhania
Michael Christopher Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of DE3765243D1 publication Critical patent/DE3765243D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DE8787310530T 1986-12-10 1987-11-30 Ibuprofen und codein enthaltende, stabile, feste arzneimittel. Expired - Lifetime DE3765243D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868629567A GB8629567D0 (en) 1986-12-10 1986-12-10 Therapeutic agents

Publications (1)

Publication Number Publication Date
DE3765243D1 true DE3765243D1 (de) 1990-10-31

Family

ID=10608805

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787310530T Expired - Lifetime DE3765243D1 (de) 1986-12-10 1987-11-30 Ibuprofen und codein enthaltende, stabile, feste arzneimittel.

Country Status (10)

Country Link
US (1) US4839176A (de)
EP (1) EP0274845B1 (de)
JP (1) JP2523726B2 (de)
AT (1) ATE56866T1 (de)
DE (1) DE3765243D1 (de)
ES (1) ES2035086T3 (de)
GB (1) GB8629567D0 (de)
GR (1) GR3001185T3 (de)
IE (1) IE60702B1 (de)
ZA (1) ZA879173B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8905815D0 (en) * 1989-03-14 1989-04-26 Beecham Group Plc Medicament
DE3927113C2 (de) * 1989-08-17 1993-11-25 Dolorgiet Gmbh & Co Kg Mittel zur Behandlung von schweren Schmerzzuständen und Verfahren zu ihrer Herstellung
US5164398A (en) * 1991-04-01 1992-11-17 Merck & Co., Inc. Ibuprofen-antitussive combinations
US5217965A (en) * 1991-06-17 1993-06-08 Euroceltique, S.A. Stabilized solid dosage forms of choline metal carboxymethylcellulose salicylate compositions
GB2260081B (en) * 1991-10-04 1995-11-29 Euro Celtique Sa Use of ibuprofen/codeine mixtures in treatment of chronic pain
GB9121204D0 (en) * 1991-10-04 1991-11-20 Euro Celtique Sa Medicament
IT1270239B (it) * 1994-06-17 1997-04-29 Zambon Spa Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
AUPM814994A0 (en) * 1994-09-14 1994-10-06 Sterling Winthrop Inc. Codeine-containing formulations
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
RS49982B (sr) 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
US6846495B2 (en) 1999-01-11 2005-01-25 The Procter & Gamble Company Compositions having improved delivery of actives
US7815936B2 (en) 2001-10-30 2010-10-19 Evonik Degussa Gmbh Use of granular materials based on pyrogenically produced silicon dioxide in pharmaceutical compositions
ZA200409537B (en) 2003-01-31 2006-10-25 Yamanouchi Pharma Co Ltd Stable solid medicinal composition for oral administration
JP5248733B2 (ja) * 2003-11-28 2013-07-31 エスエス製薬株式会社 揮散防止型固形製剤およびその製造方法
US7358270B2 (en) 2004-01-30 2008-04-15 Astellas Pharma Inc. Treating agent for irritable bowel syndrome
ES2393128T3 (es) * 2006-10-20 2012-12-18 Bayer Consumer Care Ag Ibuprofeno contra la tos
JP2008266270A (ja) * 2007-04-25 2008-11-06 Kowa Co イブプロフェン、トラネキサム酸及び糖アルコールを含有する固形製剤
PT2279731E (pt) * 2008-04-23 2013-08-30 Farmasierra Mfg S L Composição farmacêutica melhorada contendo ibuprofeno e codeína
ES2365961B1 (es) 2010-03-30 2013-01-24 Farmasierra Manufacturing S.L. Formulación farmacéutica a base de ibuprofeno y codeína de estabilidad mejorada.
CA2865917C (en) * 2011-03-01 2020-09-29 4413261 Canada Inc. (Spencer Canada) Two speed monolithic system for controlled release of drugs
JP6075043B2 (ja) * 2012-12-05 2017-02-08 大正製薬株式会社 固形製剤
FR3144752A1 (fr) 2023-01-10 2024-07-12 Song Huang Utilisation de polysulfate de pentosane pour le traitement de la toux seche

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3792170A (en) * 1972-03-14 1974-02-12 Merck & Co Inc Novel alkylsulfinyl derivatives for pain,fever and inflammation
US3936528A (en) * 1974-02-13 1976-02-03 Syntex Corporation Analgesic formulations having enhanced therapeutic activity
US4029798A (en) * 1975-06-02 1977-06-14 Sumitomo Chemical Company, Limited Analgetic composition
GB1573421A (en) * 1976-05-21 1980-08-20 Ici Ltd Acetic acid derivatives
GB1599518A (en) * 1977-02-21 1981-10-07 Ici Ltd 1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof
GB1599181A (en) * 1977-04-01 1981-09-30 Ici Ltd Oxyalkanoic acid derivatives
US4215117A (en) * 1978-05-26 1980-07-29 The Upjohn Company Stable pharmaceutical formulations
DE2962124D1 (en) * 1978-05-26 1982-03-25 Ici Plc Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture
US4315936A (en) * 1979-12-17 1982-02-16 Ortho Pharmaceutical Corporation Analgesic composition
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
US4439453A (en) * 1980-12-22 1984-03-27 Monsanto Company Directly compressible acetaminophen granulation
JPS584720A (ja) * 1981-06-26 1983-01-11 ザ・アツプジヨン・カンパニ− 鎮痛用医薬組成物
US4489080A (en) * 1981-06-26 1984-12-18 The Upjohn Company Process for analgesic treatment
US4404210A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4464376A (en) * 1982-07-22 1984-08-07 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
CA1261260A (en) * 1984-04-16 1989-09-26 Anil Salpekar Directly compressible codeine salt compositions
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4587252A (en) * 1984-12-18 1986-05-06 Brighton Pharmaceutical, Inc. Hydrocodone/ibuprofen pharmaceutical compositions and method
US4571400A (en) * 1984-12-18 1986-02-18 Belleview Pharmaceutical, Inc. Dihydrocodeine/ibuprofen pharmaceutical compositions and method
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition

Also Published As

Publication number Publication date
EP0274845B1 (de) 1990-09-26
US4839176A (en) 1989-06-13
IE873238L (en) 1988-06-10
GR3001185T3 (en) 1992-06-30
JP2523726B2 (ja) 1996-08-14
JPS63165320A (ja) 1988-07-08
GB8629567D0 (en) 1987-01-21
EP0274845A1 (de) 1988-07-20
ES2035086T3 (es) 1993-04-16
ZA879173B (en) 1988-06-03
IE60702B1 (en) 1994-08-10
ATE56866T1 (de) 1990-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition