DE3683549D1 - 4,7-dihydrothieno(2,3-b)pyridinderivate, verfahren zu ihrer herstellung und mittel fuer kardiovaskulaere krankheiten. - Google Patents

4,7-dihydrothieno(2,3-b)pyridinderivate, verfahren zu ihrer herstellung und mittel fuer kardiovaskulaere krankheiten.

Info

Publication number
DE3683549D1
DE3683549D1 DE8686108103T DE3683549T DE3683549D1 DE 3683549 D1 DE3683549 D1 DE 3683549D1 DE 8686108103 T DE8686108103 T DE 8686108103T DE 3683549 T DE3683549 T DE 3683549T DE 3683549 D1 DE3683549 D1 DE 3683549D1
Authority
DE
Germany
Prior art keywords
dihydrothieno
production
cardiovascular diseases
pyridine derivatives
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686108103T
Other languages
English (en)
Inventor
Ikuo Adachi
Yoshiharu Hiramatsu
Motohiko Ueda
Masaru Kawakami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE3683549D1 publication Critical patent/DE3683549D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8686108103T 1985-07-03 1986-06-13 4,7-dihydrothieno(2,3-b)pyridinderivate, verfahren zu ihrer herstellung und mittel fuer kardiovaskulaere krankheiten. Expired - Fee Related DE3683549D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60147054A JPS6210087A (ja) 1985-07-03 1985-07-03 ４，７−ジヒドロチエノ〔２，３−ｂ〕ピリジン誘導体，その製造法および循環器系疾患治療剤

Publications (1)

Publication Number Publication Date
DE3683549D1 true DE3683549D1 (de) 1992-03-05

Family

ID=15421457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686108103T Expired - Fee Related DE3683549D1 (de) 1985-07-03 1986-06-13 4,7-dihydrothieno(2,3-b)pyridinderivate, verfahren zu ihrer herstellung und mittel fuer kardiovaskulaere krankheiten.

Country Status (7)

Country Link
US (1) US4703051A (de)
EP (1) EP0207345B1 (de)
JP (1) JPS6210087A (de)
KR (1) KR930005175B1 (de)
DE (1) DE3683549D1 (de)
DK (1) DK174026B1 (de)
GB (1) GB2177400B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4777167A (en) * 1986-04-09 1988-10-11 Ortho Pharmaceutical Corporation Pharmaceutically useful substituted thiacycloalkeno [3,2-b]pyridines, compositions and method of use
US4874760A (en) * 1987-01-09 1989-10-17 Toa Eiyo, Ltd. 4,7-dihydroisothiazolo(5,4-b)pyridine derivatives and cardiovascular treating agents containing said derivatives
GB8801491D0 (en) * 1988-01-22 1988-02-24 Beecham Group Plc Novel compounds
US5026698A (en) * 1988-11-02 1991-06-25 Nissan Chemical Industries, Ltd. Thienopyridine type mevalonolactones
JP3179132B2 (ja) * 1990-07-04 2001-06-25 塩野義製薬株式会社 非粘着性皮膜形成法
JP2632754B2 (ja) * 1991-05-21 1997-07-23 塩野義製薬株式会社 脳内グルタミン酸遊離抑制剤
US6037340A (en) * 1997-05-28 2000-03-14 Cadus Pharmaceutical Corporation Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds
JP3046589U (ja) * 1997-08-26 1998-03-10 株式会社三栄マシニング モンキ−スパナ−
ZA200605471B (en) * 2003-12-23 2007-11-28 Dow Agrosciences Llc Process for the preparation of pyridine derivatives
JP2007230869A (ja) * 2004-04-05 2007-09-13 Takeda Chem Ind Ltd アルドステロン受容体拮抗剤
EP1965796A2 (de) * 2005-12-20 2008-09-10 Gilead Colorado, Inc. 4,7-dihydrothien-[2,3-b]pyridin-verbindungen und pharmazeutische zusammensetzungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2310746A1 (de) * 1973-03-03 1974-09-12 Bayer Ag Verfahren zur herstellung von neuen 1,4-dihydrochinolinen sowie ihre verwendung als arzneimittel
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DD210278A5 (de) * 1982-03-05 1984-06-06 Boehringer Ingelheim Kg Verfahren zur herstellung neuer basisch substituierter 4-phenyl-4,5,6,7-tetrahydro-thieno-(2,3-c)pyridine
JPS5965089A (ja) * 1982-10-05 1984-04-13 Shionogi & Co Ltd ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法
JPS6056979A (ja) * 1983-09-08 1985-04-02 Shionogi & Co Ltd ４，７−ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法

Also Published As

Publication number Publication date
GB2177400A (en) 1987-01-21
JPS6210087A (ja) 1987-01-19
US4703051A (en) 1987-10-27
JPH0556358B2 (de) 1993-08-19
DK315486A (da) 1987-01-04
KR930005175B1 (ko) 1993-06-16
DK174026B1 (da) 2002-04-29
EP0207345A3 (en) 1988-02-24
EP0207345B1 (de) 1992-01-22
GB2177400B (en) 1989-04-05
DK315486D0 (da) 1986-07-02
KR870001214A (ko) 1987-03-12
EP0207345A2 (de) 1987-01-07
GB8616238D0 (en) 1986-08-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee