DE3673325D1 - Verfahren zur herstellung von heterocyclischen verbindungen. - Google Patents

Verfahren zur herstellung von heterocyclischen verbindungen.

Info

Publication number
DE3673325D1
DE3673325D1 DE8686308207T DE3673325T DE3673325D1 DE 3673325 D1 DE3673325 D1 DE 3673325D1 DE 8686308207 T DE8686308207 T DE 8686308207T DE 3673325 T DE3673325 T DE 3673325T DE 3673325 D1 DE3673325 D1 DE 3673325D1
Authority
DE
Germany
Prior art keywords
sup
compound
heterocyclic compounds
sub
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686308207T
Other languages
English (en)
Inventor
David Frank Hayman
Alastair Couper Brodie
Panayiotis Alexandro Procopiou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3673325D1 publication Critical patent/DE3673325D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8686308207T 1985-10-23 1986-10-22 Verfahren zur herstellung von heterocyclischen verbindungen. Expired - Fee Related DE3673325D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858526209A GB8526209D0 (en) 1985-10-23 1985-10-23 Chemical process

Publications (1)

Publication Number Publication Date
DE3673325D1 true DE3673325D1 (de) 1990-09-13

Family

ID=10587162

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686308207T Expired - Fee Related DE3673325D1 (de) 1985-10-23 1986-10-22 Verfahren zur herstellung von heterocyclischen verbindungen.

Country Status (8)

Country Link
US (1) US4837336A (de)
EP (1) EP0221725B1 (de)
JP (1) JPS62174068A (de)
AT (1) ATE55385T1 (de)
DE (1) DE3673325D1 (de)
ES (1) ES2017464B3 (de)
GB (1) GB8526209D0 (de)
GR (1) GR3000742T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
WO1998051680A1 (fr) * 1997-05-12 1998-11-19 Daiso Co., Ltd. Procede pour produire des derives de 1,4-benzodioxane
GB2503187A (en) 2011-09-15 2013-12-25 Univ Sussex Composition for use in the treatment of neurodevelopmental disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB565573A (en) * 1942-01-05 1944-11-16 Geigy Ag J R Manufacture of dioxane derivatives
FR1231686A (fr) * 1957-12-21 1960-09-30 Thomae Gmbh Dr K Procédé de préparation de dérivés du 1, 4-benzènedioxane
US3829441A (en) * 1962-01-29 1974-08-13 Smith Kline French Lab Guanidinoalkylbenzodioxan derivatives
GB1001479A (en) * 1962-10-10 1965-08-18 Angeli Inst Spa Glycerol ethers
DE1493741A1 (de) * 1965-09-11 1969-04-30 Hoechst Ag Verfahren zur Herstellung von Brenzkatechin-mono-oxyalkylaethern
DE1518042C3 (de) * 1965-11-11 1975-04-10 Merck Patent Gmbh, 6100 Darmstadt 1,4-Benzodioxanderivate und Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
US3992432A (en) * 1967-04-05 1976-11-16 Continental Oil Company Phase transfer catalysis of heterogeneous reactions by quaternary salts
GB1330652A (en) * 1970-01-16 1973-09-19 Catomance Ltd 1-aryloxy-2-propanols
US4039676A (en) * 1975-06-23 1977-08-02 Ciba-Geigy Corporation 2-piperidinoalkyl-1,4-benzodioxans
JPS54103878A (en) * 1978-01-30 1979-08-15 Ciba Geigy Ag Stereosingular manufacture of 22oxiranyll 1*44benzodioxane
US4212808A (en) * 1979-03-09 1980-07-15 Ciba-Geigy Corporation 2-Oxiranyl-1,4-benzodioxans
IL70034A0 (en) * 1982-10-25 1984-01-31 Glaxo Group Ltd Heterocyclic amino compounds,their preparation and pharmaceutical compositions containing them
FI84069C (fi) * 1984-04-24 1991-10-10 Glaxo Group Ltd Foerfarande foer framstaellning av en terapeutiskt aktiv heterocyklisk aminofoerening.

Also Published As

Publication number Publication date
EP0221725B1 (de) 1990-08-08
EP0221725A3 (en) 1988-03-23
ATE55385T1 (de) 1990-08-15
JPS62174068A (ja) 1987-07-30
GR3000742T3 (en) 1991-10-10
GB8526209D0 (en) 1985-11-27
EP0221725A2 (de) 1987-05-13
US4837336A (en) 1989-06-06
ES2017464B3 (es) 1991-02-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee